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1-hydroxyquinolin-4-one oxime

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Identification
Molecular formula
C9H7N2O2
CAS number
7598-16-7
IUPAC name
1-hydroxyquinolin-4-one oxime
State
State

At room temperature, 1-hydroxyquinolin-4-one oxime typically exists as a crystalline solid. It is stable under standard conditions of temperature and pressure.

Melting point (Celsius)
228.00
Melting point (Kelvin)
501.15
Boiling point (Celsius)
341.00
Boiling point (Kelvin)
614.15
General information
Molecular weight
174.17g/mol
Molar mass
174.1680g/mol
Density
1.3660g/cm3
Appearence

The compound is generally presents as a crystalline solid. It can appear as a powder that may vary in color, often being off-white or slightly gray. The crystalline nature is typical for many oxime derivatives derived from quinolines.

Comment on solubility

Solubility of 1-hydroxyquinolin-4-one oxime

1-hydroxyquinolin-4-one oxime, a compound notable for its unique structural features, exhibits specific solubility characteristics that are crucial for its applications. When evaluating its solubility, consider the following aspects:

  • Solvent Dependence: This compound is generally soluble in organic solvents such as ethanol and dichloromethane, but shows limited solubility in polar solvents like water.
  • pH Influence: The solubility can vary with pH changes, potentially increasing in more acidic conditions due to protonation effects that enhance its solubility in aqueous solutions.
  • Temperature Effects: As with many organic compounds, higher temperatures may improve solubility, allowing better dissolution in suitable solvents.

It is essential to note that the solubility of this compound plays a critical role in its efficacy in various applications, including pharmaceutical formulations. Keep in mind that factors such as molecular structure and intermolecular interactions are pivotal in determining solubility behavior. Understanding these nuances can vastly improve handling and utilization in practical scenarios.

Interesting facts

Interesting Facts about 1-Hydroxyquinolin-4-one Oxime

1-Hydroxyquinolin-4-one oxime is an intriguing compound that resides at the intersection of organic chemistry and biological applications. Here are some captivating insights about this unique molecule:

  • Chemical Structure: The compound features a quinoline skeleton, which is known for its aromatic properties and ability to participate in various chemical reactions. This aromatic ring lends the compound stability and versatility in synthetic pathways.
  • Applications in Medicine: 1-hydroxyquinolin-4-one oxime derivatives have shown promising activity in pharmaceutical research, particularly in the development of anti-cancer and anti-inflammatory agents. This highlights the importance of oxime functionality, which can enhance biological activity.
  • Coordination Chemistry: This compound can form coordination complexes with several metal ions, making it a candidate for various catalytic processes and studies in metallobiochemistry.
  • Analytical Uses: Chemists often utilize 1-hydroxyquinolin-4-one oxime as a reagent in analytical chemistry. Its ability to selectively bind to certain metal ions makes it useful for detecting and quantifying metals in different samples.
  • Research Significance: Ongoing research into this compound continues to unveil its potential applications in material science and nanotechnology, aiding scientists in exploring new avenues for innovation.

As researchers delve deeper into the functional capabilities of 1-hydroxyquinolin-4-one oxime, they continually uncover its myriad applications, making it a compound worth noting in any chemical study. With applications that span from medicinal chemistry to materials science, this compound is a testament to the excitement and potential within the field of chemistry.

Synonyms
N-(1-hydroxyquinolin-4-ylidene)hydroxylamine
4-(hydroxyimino)quinolin-1-ol
NS00126216
T72491
4-(HYDROXYAMINO)QUINOLIN-1-IUM-1-OLATE