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N-Acetylimidazole

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Identification
Molecular formula
C5H6N2O
CAS number
1624-02-8
IUPAC name
1-imidazol-1-ylethanone
State
State

At room temperature, N-Acetylimidazole exists in a solid state. It typically forms crystalline structures, providing it a firm structure unless exposed to conditions above its melting point where it transitions into a liquid state.

Melting point (Celsius)
89.00
Melting point (Kelvin)
362.00
Boiling point (Celsius)
276.50
Boiling point (Kelvin)
549.70
General information
Molecular weight
122.14g/mol
Molar mass
122.1380g/mol
Density
1.1660g/cm3
Appearence

N-Acetylimidazole typically appears as a white to off-white crystalline powder. Its crystalline nature makes it solid and slightly glossy under light. It may also appear as colorless crystals when extremely pure.

Comment on solubility

Solubility of 1-imidazol-1-ylethanone

1-imidazol-1-ylethanone is a compound that exhibits interesting solubility characteristics. Its solubility can be influenced by various factors, including:

  • Polarity: Being a polar molecule, 1-imidazol-1-ylethanone is generally soluble in polar solvents like water.
  • Hydrogen Bonding: The presence of functional groups allows for the formation of hydrogen bonds, further enhancing solubility in protic solvents.
  • Temperature: In many cases, an increase in temperature can lead to a higher solubility due to enhanced molecular interactions.

It is frequently noted that “Like dissolves like,” meaning that due to its polar nature, it may not be as soluble in nonpolar solvents such as hydrocarbons.

For practical applications and laboratory preparations, it's beneficial to consider these factors when working with 1-imidazol-1-ylethanone to achieve desired concentrations and reactions.

Interesting facts

Interesting Facts About 1-Imidazol-1-ylethanone

1-Imidazol-1-ylethanone is a fascinating compound that plays significant roles in various scientific fields, particularly in organic chemistry and pharmaceuticals. Here are some interesting aspects of this compound:

  • Structural Significance: The imidazole ring in the structure contributes to its unique reactivity and properties, making it an essential building block in many organic syntheses.
  • Pharmacological Potential: Compounds like 1-imidazol-1-ylethanone are often studied for their potential biological activities, including antifungal and antibacterial properties, which can lead to the development of novel medications.
  • Catalyst Potential: This compound may serve as an intermediate in creating catalysts that facilitate various chemical reactions, especially in the field of asymmetric synthesis.
  • Research Interest: Ongoing research continues to uncover more about its mechanism of action and interaction with biological systems, highlighting its relevance in medicinal chemistry.
  • Versatility: 1-Imidazol-1-ylethanone can participate in diverse reactions, making it valuable in synthesizing more complex molecules, including those found in natural products.

As researchers delve deeper into the properties and applications of 1-imidazol-1-ylethanone, it is poised to become even more significant in advancing both theoretical knowledge and practical advancements within the realm of chemistry. The intriguing nature of this compound exemplifies the beauty and complexity inherent in chemical science.

Synonyms
1-Acetylimidazole
N-Acetylimidazole
2466-76-4
1-(1H-imidazol-1-yl)ethanone
1H-Imidazole, 1-acetyl-
Acetylimidazole
1-Acetyl-1H-imidazole
1-imidazol-1-ylethanone
Ethanone, 1-(1H-imidazol-1-yl)-
IMIDAZOLE, 1-ACETYL-
CCRIS 6534
EINECS 219-577-7
ZMP8X1Y11G
BRN 0108425
CHEBI:16984
DTXSID8062440
5-23-04-00218 (Beilstein Handbook Reference)
DTXCID8037120
219-577-7
1-(1H-imidazol-1-yl)ethan-1-one
MFCD00005287
3-acetylimidazole
UNII-ZMP8X1Y11G
N-acetyl imidazole
1- acetylimidazole
1-acetyl imidazole
imidazole, N-acetyl-
1-Acetylimidazole, 98%
Imidazole N-1 deriv. 5
OZAGREL IMPURITY 1
1-Acetyl-1H-imidazole #
1-(methylcarbonyl)imidazole
SCHEMBL26238
MLS001074864
BDBM7944
CHEMBL1592087
HMS2234I07
HY-D0181
AKOS005208084
AC-7521
NCGC00246992-01
AS-11932
SMR000568396
SY049533
DB-031677
A0694
CS-0010103
NS00046189
C02560
EN300-748826
1-Acetylimidazole, Vetec(TM) reagent grade, 98%
Q27102162
Z1255402643