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1-Indolin-4-ylethanone

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Identification
Molecular formula
C10H11NO
CAS number
111130-80-8
IUPAC name
1-indolin-4-ylethanone
State
State

At room temperature, 1-Indolin-4-ylethanone is usually found in the solid state, forming crystalline structures that may be colorless or have a slight yellow hue, depending on its specific form and level of purity.

Melting point (Celsius)
73.00
Melting point (Kelvin)
346.15
Boiling point (Celsius)
275.00
Boiling point (Kelvin)
548.15
General information
Molecular weight
147.18g/mol
Molar mass
147.1840g/mol
Density
1.1380g/cm3
Appearence

1-Indolin-4-ylethanone typically appears as a solid crystalline substance. The crystals are often colorless or pale yellow, depending on purity and specific conditions. They have a characteristic aromatic odor that is common to many organic compounds with similar structures.

Comment on solubility

Solubility of 1-Indolin-4-ylethanone

1-Indolin-4-ylethanone, with the chemical formula C10H11NO, exhibits intriguing solubility characteristics that are essential for its applications in various fields.

Generally, the solubility of organic compounds like 1-indolin-4-ylethanone can be influenced by several factors, including:

  • Polarity: 1-Indolin-4-ylethanone is a non-polar to slightly polar compound, often leading to increased solubility in non-polar solvents.
  • Hydrophobic interactions: Its aromatic structure contributes to hydrophobicity, making it less soluble in water but more soluble in organic solvents.
  • Temperature: Increasing temperatures can enhance solubility in various solvents.

In summary, while 1-indolin-4-ylethanone is sparingly soluble in water, it can readily dissolve in:

  • Alcohols (like ethanol)
  • Aromatic hydrocarbons (such as toluene)
  • Other organic solvents that complement its structural attributes.

Understanding these solubility traits is crucial for researchers working with this compound in synthesis and formulation processes. As one might say, "The solubility of a compound is just as important as its reactivity."

Interesting facts

Exploring 1-Indolin-4-ylethanone

1-Indolin-4-ylethanone is a fascinating compound that belongs to the category of indole derivatives, which are known for their significant biological activities and wide ranging applications in medicinal chemistry.

Key Characteristics

  • Biological Relevance: Compounds like 1-indolin-4-ylethanone have been studied for their potential as antitumor agents. Their structure allows them to interact with various biological targets, offering possibilities for drug development.
  • Synthesis Methods: The synthesis of 1-indolin-4-ylethanone can involve a variety of techniques, including traditional methods and innovative green chemistry approaches, underlining the compound's adaptability for research and industrial applications.
  • Structural Insight: Being based on an indole scaffold, compounds like 1-indolin-4-ylethanone often exhibit interesting electronic properties adjusted by functional group positioning, making them favorable for designing novel materials.

Applications in Research

This compound has garnered interest in several research areas due to its versatile nature:

  1. Pharmaceutical Development: Researchers are particularly interested in its role in creating new therapeutic agents that target specific diseases.
  2. Organic Synthesis: Due to its unique structure, it acts as a building block for synthesizing more complex molecules.
  3. Material Science: The compound's properties make it suitable for developing new materials with specific electronic or optical characteristics.

Conclusion

In summary, 1-indolin-4-ylethanone is not just a simple compound, but a gateway into the vast realm of organic chemistry and its numerous practical applications. As research continues to evolve, compounds like this will undoubtedly play a pivotal role in advancing both science and technology.

Synonyms
Indoline, 5-acetyl-
NSC 75568
KETONE, 5-INDOLINYL METHYL
EINECS 240-223-2
BRN 0131199
AI3-52427
4-21-00-03670 (Beilstein Handbook Reference)
Ethanone, 1-(2,3-dihydro-1H-indol-5-yl)-(9CI)
16078-34-5
Ethanone, 1-(2,3-dihydro-1H-indol-5-yl)-
1-(2,3-dihydro-1H-indol-4-yl)ethanone
1-(indolin-4-yl)ethanone
N3D2N89RVV
SCHEMBL24348808
1-(2,3-dihydro-1H-indol-4-yl)ethan-1-one
1779853-88-1