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3-Nitroiodobenzene

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Identification
Molecular formula
C6H4INO2
CAS number
636-98-6
IUPAC name
1-iodo-3-nitro-benzene
State
State

At room temperature, 3-Nitroiodobenzene is generally in a solid crystalline state.

Melting point (Celsius)
49.00
Melting point (Kelvin)
322.15
Boiling point (Celsius)
282.00
Boiling point (Kelvin)
555.15
General information
Molecular weight
248.00g/mol
Molar mass
248.0080g/mol
Density
2.0060g/cm3
Appearence

3-Nitroiodobenzene typically appears as a yellow crystalline solid. The crystalline structure is well-defined and reflects light, giving it a distinct appearance compared to other chemical compounds.

Comment on solubility

Solubility of 1-Iodo-3-nitro-benzene

The solubility characteristics of 1-iodo-3-nitro-benzene (C6H4INO2) are quite intriguing due to its unique structure. This compound is primarily recognized for its non-polar characteristics which affect its behavior in various solvents.

Key Points about Solubility:

  • Polar Solvents: 1-iodo-3-nitro-benzene shows limited solubility in polar solvents like water. The presence of the nitro group (–NO2) provides some degree of polarity, but the overall compound is still relatively hydrophobic.
  • Non-Polar Solvents: The compound is more soluble in non-polar solvents such as benzene and toluene, owing to the similar non-polar characteristics.
  • Temperature Dependence: The solubility of 1-iodo-3-nitro-benzene can also be influenced by temperature; generally, an increase in temperature enhances solubility in organic solvents.
  • Functional Group Influence: The iodo group (–I) and the nitro group (–NO2) affect the interactions with solvents, imparting diverse solubility patterns.

In conclusion, while 1-iodo-3-nitro-benzene can demonstrate some solubility in organic media, its overall compatibility with polar solvents remains limited, marking it as a fascinating subject for further study in the field of solubility and solvent interactions.

Interesting facts

Interesting Facts about 1-Iodo-3-nitro-benzene

1-Iodo-3-nitro-benzene, an aromatic compound, is notable not only for its unique structure but also for its diverse applications in organic chemistry and materials science. Here are some intriguing facts that highlight its significance:

  • Functional Groups: This compound contains both an iodo and a nitro group, which greatly influence its reactivity and properties. The presence of these groups allows for various chemical transformations.
  • Uses in Synthesis: 1-Iodo-3-nitro-benzene serves as an important intermediate in the synthesis of pharmaceuticals, agrochemicals, and dyes. The versatility of this compound enables chemists to create numerous derivatives for specialized applications.
  • Reactivity: The compound is more reactive than simpler benzene derivatives due to the electron-withdrawing nature of the nitro group, which deactivates the aromatic ring in electrophilic substitution reactions while simultaneously directing further substitutions at the ortho and para positions.
  • Role in Medicinal Chemistry: Compounds like 1-iodo-3-nitro-benzene have drawn attention for their potential therapeutic applications, particularly in the enhancement of biocompatibility and the development of targeted drug delivery systems.
  • Nitro Group Importance: The nitro group is instrumental in various applications, facilitating conjugation reactions and acting as a signaling molecule in certain biochemical processes.

In conclusion, 1-iodo-3-nitro-benzene represents a fascinating intersection of functional group chemistry and practical application. Its diverse roles make it a valuable compound for further study in both academic and industrial settings. As chemists continue to explore the potential of such compounds, the discoveries may lead to innovative materials and breakthroughs in drug development.

Synonyms
1-Iodo-3-nitrobenzene
645-00-1
3-Iodonitrobenzene
M-IODONITROBENZENE
Benzene, 1-iodo-3-nitro-
3-nitroiodobenzene
M-NITROIODOBENZENE
3-iodo-1-nitrobenzene
3-I-nitrobenzene
iodo-3-nitrobenzene
meta-nitroiodobenzene
F6TCH3TLL9
NSC 3538
EINECS 211-427-9
DTXSID5025449
CHEBI:67123
AI3-15390
NSC-3538
M-NITROPHENYL IODIDE
3-NITROPHENYL IODIDE
3-NITRO-1-IODOBENZENE
DTXCID105449
IODO-3-NITROBENZENE, 1-
mIodonitrobenzene
mNitroiodobenzene
3iodonitrobenzene
3Nitroiodobenzene
3Iodo1nitrobenzene
mNitrophenyl iodide
3Nitrophenyl iodide
Benzene, 1iodo3nitro
211-427-9
inchi=1/c6h4ino2/c7-5-2-1-3-6(4-5)8(9)10/h1-4
meta-iodonitrobenzene
1-Iodo-3-nitro-benzene
MFCD00007218
NSC3538
3-nitro-iodobenzen
m-nitro-iodobenzene
3-nitro-iodobenzene
1iodo-3-nitrobenzene
1-Iiodo-3-nitrobenzene
1 -iodo-3-nitrobenzene
UNII-F6TCH3TLL9
ghl.PD_Mitscher_leg0.931
MLS002152852
SCHEMBL177151
CHEMBL115511
1-Iodo-3-nitrobenzene, 99%
Tox21_201085
AKOS009156587
GS-3279
NCGC00091693-01
NCGC00091693-02
NCGC00258637-01
AC-22936
CAS-645-00-1
SMR001224476
DB-024189
A8828
I0063
NS00035704
EN300-175865
Q27135633