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1-Iodo-2-naphthol

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Identification
Molecular formula
C10H7IO
CAS number
118-75-2
IUPAC name
1-iodonaphthalen-2-ol
State
State

At room temperature, 1-Iodo-2-naphthol is a crystalline solid. It is usually stored in a dry and light-protected environment to maintain its stability.

Melting point (Celsius)
126.50
Melting point (Kelvin)
399.70
Boiling point (Celsius)
372.60
Boiling point (Kelvin)
645.80
General information
Molecular weight
270.07g/mol
Molar mass
270.0750g/mol
Density
2.0540g/cm3
Appearence

1-Iodo-2-naphthol is a crystalline solid with a pale yellow to brown color. It tends to appear as elongated needle-like crystals or as powdery masses. This compound is sensitive to light and moisture, which may affect its coloration over time.

Comment on solubility

Solubility of 1-iodonaphthalen-2-ol

1-iodonaphthalen-2-ol, with its unique structure, exhibits some interesting solubility properties:

  • Polarity: The presence of the hydroxyl group (-OH) contributes to the molecule's polarity, which generally enhances its ability to interact with polar solvents.
  • Solvent Compatibility: This compound is somewhat soluble in common polar solvents such as ethanol and methanol, thanks to hydrogen bonding potential of the hydroxyl group.
  • Non-Polar Solubility: However, due to the naphthalene scaffold, it also demonstrates some degree of solubility in non-polar solvents like hexane and benzene.
  • Overall Solubility: The solubility of 1-iodonaphthalen-2-ol can be described as moderate, which makes it versatile for use in various chemical reactions and applications.

In summary, when engaging with this compound, one might find it beneficial to consider the solvent system used, as its solubility is influenced by both polar and non-polar interactions, creating a unique balance.

Interesting facts

Interesting Facts about 1-Iodonaphthalen-2-ol

1-Iodonaphthalen-2-ol is a captivating compound that sits at the intersection of chemistry and practical applications. Here are a few noteworthy details:

  • Structural Significance: This compound features a unique combination of a naphthalene ring system and an iodine substituent, which plays a crucial role in its reactivity and properties.
  • Synthetic Utility: 1-Iodonaphthalen-2-ol is often utilized as a versatile intermediate in organic synthesis, enabling the creation of more complex molecules through its functional groups.
  • Biological Relevance: Compounds containing iodine, such as 1-iodonaphthalen-2-ol, have gained interest in medicinal chemistry due to their potential antimicrobial and antitumor activities. This highlights the importance of nitrogen-containing compounds in drug development.
  • Reaction Versatility: The iodine atom in this compound serves as a **leaving group** in various reactions, including electrophilic aromatic substitution, making it a valuable participant in numerous synthetic pathways.
  • Reflecting on Properties: The aromatic nature of the naphthalene framework confers stability to the molecule, while the hydroxyl group contributes to potential hydrogen bonding capabilities. This combination can influence solubility and reactivity.

The exploration of compounds like 1-iodonaphthalen-2-ol not only enhances our understanding of organic chemistry but also opens avenues for innovations in material science and pharmaceuticals. As we continue to unravel the complexities of such compounds, we gain deeper insights into their transformative potential in various fields.

Synonyms
1-Iodo-2-naphthol
2033-42-3
2-Naphthalenol, 1-iodo-
2-NAPHTHOL, 1-IODO-
NSC 87885
BRN 2518177
1-iodo-2-naphthalenol
DTXSID70174227
2Naphthol, 1iodo
2Naphthalenol, 1iodo
2Naphthalenol, 1iodo (9CI)
DTXCID6096718
2-Naphthalenol, 1-iodo-(9CI)
622-389-1
1-iodonaphthalen-2-ol
MFCD00046371
ZL6HVL58XX
NSC-87885
ss-Naphtholjodid
NSC87885
UNII-ZL6HVL58XX
1-iodo-2-hydroxynaphthalene
WLN: L66J BI CQ
SCHEMBL1602273
JEVGGOSILOIIHN-UHFFFAOYSA-N
AKOS015913446
CS-W002225
DS-2289
SY019655