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Menthol

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Identification
Molecular formula
C10H20O
CAS number
2216-51-5
IUPAC name
1-isopropyl-4-methyl-bicyclo[3.1.0]hexan-3-ol
State
State

Menthol is typically a solid at room temperature, existing in crystalline form. It is known for its minty aroma and flavor.

Melting point (Celsius)
42.00
Melting point (Kelvin)
315.15
Boiling point (Celsius)
212.00
Boiling point (Kelvin)
485.15
General information
Molecular weight
156.27g/mol
Molar mass
156.2690g/mol
Density
0.8909g/cm3
Appearence

Menthol appears as colorless crystals or a white crystalline powder. It has a distinctive minty odor and a cooling taste that is associated with mint products. The compound is often used for its aromatic and medicinal properties, and in its pure form, it forms needle-like crystals.

Comment on solubility

Solubility of 1-isopropyl-4-methyl-bicyclo[3.1.0]hexan-3-ol

When it comes to the solubility of 1-isopropyl-4-methyl-bicyclo[3.1.0]hexan-3-ol, it is important to understand its structural characteristics which influence how it interacts with solvents. This compound, due to its bicyclic structure and hydroxyl group, possesses some unique solubility traits:

  • Polar vs. Non-Polar Solvents: The presence of the hydroxyl (-OH) group greatly enhances its solubility in polar solvents such as water and alcohols.
  • Hydrogen Bonding: The -OH group can form hydrogen bonds, which facilitates dissolution in polar media.
  • Hydrophobic Character: Parallel to its polar attributes, the hydrocarbon framework contributes to some hydrophobic character, potentially making it less soluble in non-polar solvents.

Overall, its solubility profile can be summarized as follows:

  • Highly soluble: in water and other polar solvents due to hydrogen bonding.
  • Limited solubility: in non-polar solvents like hexane or toluene, due to hydrophobic structure.

In conclusion, while 1-isopropyl-4-methyl-bicyclo[3.1.0]hexan-3-ol exhibits significant solubility in polar environments due to its functional group, its solubility in non-polar environments remains constrained, highlighting the classic solubility rule: "Like dissolves like."

Interesting facts

Exploring 1-isopropyl-4-methyl-bicyclo[3.1.0]hexan-3-ol

1-isopropyl-4-methyl-bicyclo[3.1.0]hexan-3-ol is a fascinating compound that belongs to the realm of bicyclic alcohols. Here are some intriguing facts about this unique molecule:

  • Structural Intricacies: The structure of this compound showcases a bicyclic framework, which means it contains two fused rings. This specific arrangement contributes to its distinct chemical properties.
  • Chiral Centers: One of the remarkable features of 1-isopropyl-4-methyl-bicyclo[3.1.0]hexan-3-ol is the presence of chiral centers, which allows for stereoisomerism. This can give rise to different physical and chemical behaviors among its isomers.
  • Potential Applications: Compounds like this one are often explored in medicinal chemistry for their potential therapeutic effects. Their unique structures can interact with biological systems in interesting ways.
  • Natural Occurrences: Alcohols similar to 1-isopropyl-4-methyl-bicyclo[3.1.0]hexan-3-ol may be found in various natural sources, whereby they could play a role in the olfactory properties of certain plants.
  • Chemical Reactions: As an alcohol, this compound can participate in a variety of chemical reactions, such as dehydration and oxidation, thereby enriching the landscape of organic synthesis.

In conclusion, 1-isopropyl-4-methyl-bicyclo[3.1.0]hexan-3-ol exemplifies the beauty and complexity of organic chemistry. Its unique bicyclic structure and chiral nature provide numerous avenues for exploration, making it a compelling topic for scientists and students alike. As the renowned chemist Linus Pauling once said, "Chemistry is the study of substances; this is the study of the changes that they undergo." Thus, delving into compounds like 1-isopropyl-4-methyl-bicyclo[3.1.0]hexan-3-ol opens new frontiers in both scientific research and understanding nature's intricacies.

Synonyms
513-23-5
NSC407280
THUJANOL
4-methyl-1-(propan-2-yl)bicyclo[3.1.0]hexan-3-ol
35732-37-7
Thujol
Bicyclo[3.1.0]hexan-3-ol, 4-methyl-1-(1-methylethyl)-
3-Thujol
Neoisothujyl alcohol
Bicyclo(3.1.0)hexan-3-ol, 4-methyl-1-(1-methylethyl)-
Neothujol
.delta.3-thujanol
EINECS 221-933-1
EINECS 252-702-3
SCHEMBL872814
DTXSID30865003
DZVXRFMREAADPP-UHFFFAOYSA-N
Bicyclo[3.1.0]hexan-3-ol, 4-methyl-1-(1-methylethyl)-, (1.alpha.,3.beta.,4.beta.,5.alpha.)-
NSC 407280
NSC-407280
(1alpha,3alpha,4alpha,5alpha)-4-Methyl-1-(1-methylethyl)bicyclo(3.1.0)hexan-3-ol
DB-051947
NS00048204
1-Isopropyl-4-methylbicyclo[3.1.0]hexan-3-ol #
4-Methyl-1-(1-methylethyl)bicyclo(3.1.0)hexan-3-ol
Bicyclo[3.1.0]hexan-3-ol, (1.alpha.,3.alpha.,4.alpha.,5.alpha.)-
(1R-(1alpha,3alpha,4alpha,5alpha))-4-Methyl-1-(1-methylethyl)bicyclo(3.1.0)hexan-3-ol
Bicyclo(3.1.0)hexan-3-ol, 4-methyl-1-(methylethyl)-, (1alpha,3alpha,4alpha,5alpha)-