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Naproxen

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Identification
Molecular formula
C14H14O3
CAS number
22204-53-1
IUPAC name
1-(isopropylamino)-3-(1-naphthyl)propan-2-ol
State
State
Naproxen is usually in a solid state at room temperature and is available in powder form for dispensing as medication.
Melting point (Celsius)
152.00
Melting point (Kelvin)
425.15
Boiling point (Celsius)
491.90
Boiling point (Kelvin)
765.05
General information
Molecular weight
230.31g/mol
Molar mass
230.3110g/mol
Density
1.0410g/cm3
Appearence

Naproxen is a white to off-white crystalline powder with a slight odor. It is commonly encountered as a crystalline solid and is often ground into a fine powder for pharmaceutical formulations.

Comment on solubility

Solubility of 1-(isopropylamino)-3-(1-naphthyl)propan-2-ol

The solubility of 1-(isopropylamino)-3-(1-naphthyl)propan-2-ol can be influenced by several factors, including polarity and intermolecular interactions. This compound, which contains both an amine and a hydroxy group, exhibits some interesting solubility properties:

  • Polarity: The presence of the hydroxyl group provides some degree of polarity, which typically enhances solubility in polar solvents.
  • Hydrogen Bonding: The ability to form hydrogen bonds with water molecules can significantly affect its solubility. Compounds capable of such interactions often display increased solubility in aqueous solutions.
  • Hydrophobic Interactions: The naphthyl group introduces hydrophobic character, which may decrease solubility in water but can enhance solubility in organic solvents.

As a result, the solubility of this compound may be:

  • Moderate in polar solvents such as water due to hydrogen bonding.
  • Higher in non-polar organic solvents where the hydrophobic naphthyl group can interact favorably.

Understanding the balance between these opposing forces is crucial for predicting the solubility behavior of 1-(isopropylamino)-3-(1-naphthyl)propan-2-ol. In summary, while solubility can be characterized as variable, experimental data may provide the most accurate insight into real-world solubility.

Interesting facts

Interesting Facts about 1-(Isopropylamino)-3-(1-naphthyl)propan-2-ol

1-(Isopropylamino)-3-(1-naphthyl)propan-2-ol is a fascinating compound that has aroused interest in various fields of research, particularly in medicinal chemistry and organic synthesis. Here are some engaging insights into this compound:

  • Pharmacological Relevance: This compound belongs to a class of substances that exhibit potential pharmacological properties. Research indicates that it may be of interest for developing medications targeting specific therapeutic areas.
  • Structural Intricacies: The presence of an isopropylamino group along with a naphthyl moiety contributes to its unique chemical profile. The complexity of its structure allows for intriguing interactions with biological systems.
  • Intriguing Interactions: The aromatic naphthyl group can facilitate π-π interactions, which are essential for binding with biological targets, making this compound a subject of numerous studies.
  • Applications in Synthesis: Due to its unique structure, this compound can be used as an intermediate in various organic syntheses, opening avenues for producing other derivatives.
  • Research Vantage: This compound is a point of focus in studies related to drug design and development, given its diverse functional groups and potential bioactivity.

In summary, the intricate structure and potential applications of 1-(isopropylamino)-3-(1-naphthyl)propan-2-ol provide a robust platform for researchers and chemists alike. Its role in pharmacology and organic synthesis continues to inspire scientific exploration, leading to greater insights and advancements in medicinal chemistry.

Synonyms
AKOS015326162
Naphthalene, 1-(2-hydroxy-3-isopropylamino)propyloxy-