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Propranolol

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Identification
Molecular formula
C16H21NO2
CAS number
525-66-6
IUPAC name
1-(isopropylamino)-3-(3-methylphenoxy)propan-2-ol
State
State

At room temperature, this compound is in a solid state.

Melting point (Celsius)
96.00
Melting point (Kelvin)
369.15
Boiling point (Celsius)
363.00
Boiling point (Kelvin)
636.15
General information
Molecular weight
259.37g/mol
Molar mass
259.3650g/mol
Density
1.0800g/cm3
Appearence

This compound typically appears as a crystalline powder. It may be colorless or white, though the presence of impurities can sometimes affect its color. It does not have a distinct odor.

Comment on solubility

Solubility of 1-(isopropylamino)-3-(3-methylphenoxy)propan-2-ol

The solubility of the compound 1-(isopropylamino)-3-(3-methylphenoxy)propan-2-ol is influenced by a variety of factors, notably its functional groups and molecular structure. Here are some key points to consider:

  • Polarity: The presence of polar functional groups, such as the -OH (alcohol) and the -NH (amine), enhances solubility in polar solvents like water.
  • Hydrophobic interactions: The 3-methylphenoxy group contributes hydrophobic characteristics, potentially decreasing solubility in polar environments.
  • Hydrogen bonding: The ability of the compound to form hydrogen bonds with solvent molecules significantly impacts its solubility profile.
  • Temperature: Higher temperatures can generally lead to increased solubility, as molecular motion increases.

To sum up, while 1-(isopropylamino)-3-(3-methylphenoxy)propan-2-ol may exhibit moderate solubility in water due to its polar characteristics, the hydrophobicity introduced by the 3-methylphenoxy moiety may limit solubility. Testing in various solvents is advised to better understand its solubility properties.

Interesting facts

Interesting Facts about 1-(isopropylamino)-3-(3-methylphenoxy)propan-2-ol

1-(isopropylamino)-3-(3-methylphenoxy)propan-2-ol is a fascinating compound with a variety of applications and properties that make it of significant interest in the field of chemistry and pharmaceuticals.

Key Features

  • Active Ingredient: This compound is often studied for its role as an active ingredient in various therapeutic agents, particularly in the treatment of different medical conditions.
  • Structure: The unique structure of this compound, characterized by the presence of an isopropylamino group and a 3-methylphenoxy moiety, allows for specific interactions with biological systems, potentially enhancing its efficacy as a drug.
  • Synthetic Routes: Researchers have developed multiple synthetic pathways to create this compound, showcasing the versatility and adaptability of modern organic synthesis techniques.

Applications

This compound has garnered attention in diverse areas:

  • Pharmaceuticals: It has potential applications in drug development, particularly in medications targeting nerve activity and other physiological functions.
  • Research: Scientists are exploring the effects of this compound on cell signaling and receptor interactions, which could lead to groundbreaking discoveries in pharmacology.

Quote from Scientists

As one researcher put it, “The exploration of complex compounds like 1-(isopropylamino)-3-(3-methylphenoxy)propan-2-ol not only advances our understanding of chemical interactions but also opens new avenues for therapeutic innovations.”

Conclusion

Overall, 1-(isopropylamino)-3-(3-methylphenoxy)propan-2-ol stands out as a notable compound that exemplifies the intersection of organic chemistry and medicinal applications. Its study promotes further scientific inquiry and could potentially improve healthcare outcomes in the future.

Synonyms
Toliprolol
2933-94-0
Toliprolol [INN]
Doberol
1-(Isopropylamino)-3-(m-tolyloxy)-2-propanol
Toliprololum
Toliprololum [INN-Latin]
EINECS 220-905-6
UNII-DCP58J201D
BRN 1874722
DCP58J201D
2-Propanol, 1-(isopropylamino)-3-(m-tolyloxy)-
Isopropylamino-1-m-tolyloxy-3-propan-2-ol
TOLIPROLOL [MI]
KO 592 [AS HYDROCHLORIDE]
KO 592 (Salt/Mix)
ICI 45763 [AS HYDROCHLORIDE]
Isopropylamino-1-m-tolyloxy-3-propan-2-ol [German]
KO-592 FREE BASE
ICI-45763 (Salt/Mix)
2-Propanol, 1-((1-methylethyl)amino)-3-(3-methylphenoxy)-
2-Propanol, 1-[(1-methylethyl)amino]-3-(3-methylphenoxy)-
ICI-45763 FREE BASE
KOE 592
Toliprololum (INN-Latin)
1-(3-METHYLPHENOXY)-3-(ISOPROPYLAMINO)-2-PROPANOL
1-(3-METHYLPHENOXY)-2-HYDROXY-3-ISOPROPYLAMINOPROPANE
1-((1-METHYLETHYL)AMINO)-3-(3-METHYLPHENOXY)-2-PROPANOL
KO 592 (AS HYDROCHLORIDE)
ICI 45763 (AS HYDROCHLORIDE)
ICI 45,763
(+-)-1-(ISOPROPYLAMINO)-3-(M-TOLYLOXY)-2-PROPANOL
2-Propanol, 1-((1-methylethyl)amino)-3-(3-methylphenoxy)-(9CI)
220-905-6
nxqmnkuggynlby-uhfffaoysa-n
MHIP
1-(3-methylphenoxy)-3-(propan-2-ylamino)propan-2-ol
SR-01000945167
SCHEMBL79267
CHEMBL67096
DTXSID50863061
CHEBI:134918
WFA57441
AKOS008962502
NS00010648
EN300-147616
SR-01000945167-2
1-(3'-methylphenoxy)-3-(iso-propylamino)-2-propanol
1-(Isopropylamino)-3-(3-methylphenoxy)-2-propanol #
Q15633990
1-(3'-methyl-phenoxy)-3-(iso-propylamino)-2-propanol
1-(3-methylphenoxy)-3-[(propan-2-yl)amino]propan-2-ol
(+/-)-1-(ISOPROPYLAMINO)-3-(M-TOLYLOXY)-2-PROPANOL