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Alprenolol

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Identification
Molecular formula
C15H23NO1
CAS number
13655-52-2
IUPAC name
1-(isopropylamino)-3-phenyl-propan-2-ol
State
State
At room temperature, alprenolol is typically found as a solid.
Melting point (Celsius)
112.00
Melting point (Kelvin)
385.15
Boiling point (Celsius)
345.00
Boiling point (Kelvin)
618.15
General information
Molecular weight
249.35g/mol
Molar mass
249.3510g/mol
Density
1.1188g/cm3
Appearence

Alprenolol typically appears as a white or off-white crystalline powder. It may also be provided as a solid in the form of a tablet or capsule when used in medicinal applications.

Comment on solubility

Solubility of 1-(Isopropylamino)-3-phenyl-propan-2-ol

1-(Isopropylamino)-3-phenyl-propan-2-ol is a complex organic compound, and understanding its solubility is crucial for various applications in chemistry and pharmacology. Generally, the solubility of organic compounds like this one can be influenced by several factors:

  • Polarity: The presence of both an isopropylamino group and a phenyl group in the structure suggests a balance between polar and non-polar characteristics. This polarity can impact solubility in different solvents.
  • Hydrogen bonding: Due to the hydroxyl (−OH) functional group, this compound has the ability to engage in hydrogen bonding, which can enhance solubility in polar solvents like water.
  • Size of the molecule: The size and steric hindrance caused by the isopropyl group could hinder solubility in some solvents but may allow for improved interaction with lipid membranes.

In general, while 1-(isopropylamino)-3-phenyl-propan-2-ol is likely soluble in polar solvents, such as alcohols and possibly some polar organic solvents, its solubility in non-polar solvents could be limited due to its polar functional groups. Ultimately, the exact solubility can only be confirmed through experimental data.

As highlighted, the interplay of structural features plays a vital role in determining the solubility of this compound, and it serves as a fascinating example of the principles governing solubility in organic chemistry.

Interesting facts

Interesting Facts about 1-(Isopropylamino)-3-phenyl-propan-2-ol

1-(Isopropylamino)-3-phenyl-propan-2-ol, commonly known in the scientific community for its unique structural characteristics, is a fascinating compound that highlights the importance of substituent effects in organic chemistry.

Structural Insights

This compound belongs to a class of amines known for their varied pharmacological properties. The presence of both the isopropylamine group and the phenyl group introduces complexity in its reactivity and potential biological activity:

  • Isopropylamino Group: This moiety brings in steric bulk, which can influence the compound's binding interactions with biological targets.
  • Phenyl Group: The aromatic nature not only provides stability but also enhances electron delocalization, possibly affecting the compound’s overall reactivity.

Pharmacological Significance

Compounds with similar structures have been studied for their potential therapeutic effects. Here are some notable areas of interest:

  • Emerging research suggests compounds like this one may exhibit central nervous system activity, making them candidates for neuropharmacological studies.
  • Due to their amine groups, these compounds are also scrutinized for their roles in medicinal chemistry, particularly in the development of pharmaceuticals aimed at treating mood disorders and neurological conditions.

Chemical Reactions

From a synthetic chemistry perspective, 1-(isopropylamino)-3-phenyl-propan-2-ol can participate in various reaction pathways:

  • Nucleophilic Reactions: The amine moiety can act as a nucleophile, opening up pathways for further functionalization.
  • Oxidation Reactions: Its alcohol component may react under oxidative conditions, leading to diverse derivative formation.

Conclusion

In summary, 1-(isopropylamino)-3-phenyl-propan-2-ol exemplifies the intricate relationships between structure and function in organic compounds. As researchers continue to explore its properties and potential applications, this compound stands as a testament to the richness of organic chemistry and its relevance in various scientific fields.

Synonyms
19343-25-0
alpha-(((1-Methylethyl)amino)methyl)benzeneethanol
BRN 2719962
BENZENEETHANOL, alpha-(((1-METHYLETHYL)AMINO)METHYL)-
Phenethyl alcohol, .alpha.-[(isopropylamino)methyl]-
Benzeneethanol, .alpha.-[[(1-methylethyl)amino]methyl]-
.alpha.-(((1-Methylethyl)amino)methyl)benzeneethanol
alpha-[[(1-Methylethyl)amino]methyl]benzeneethanol
Phenethyl alcohol, alpha-((isopropylamino)methyl)-
RefChem:318158
SHNJNXNMYKGBGP-UHFFFAOYSA-N
1-phenyl-3-(propan-2-ylamino)propan-2-ol
SCHEMBL16570941
SCHEMBL20553029
DTXSID20941027
AKOS009132172
1-(Isopropylamino)-3-phenyl-2-propanol #
1-Phenyl-3-[(propan-2-yl)amino]propan-2-ol