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Phenylthiourea

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Identification
Molecular formula
C7H8N2S
CAS number
103-85-5
IUPAC name
1-(isopropylideneamino)-3-phenyl-isothiourea
State
State

At room temperature, phenylthiourea is typically a solid.

Melting point (Celsius)
146.00
Melting point (Kelvin)
419.15
Boiling point (Celsius)
256.50
Boiling point (Kelvin)
529.70
General information
Molecular weight
152.22g/mol
Molar mass
152.2240g/mol
Density
1.2410g/cm3
Appearence

Phenylthiourea appears as a white crystalline solid. It's a compound known for its distinct, relatively bitter taste, and is famous for being used in genetic taste testing experiments where it determines an individual's ability to taste phenylthiocarbamide (PTC).

Comment on solubility

Solubility of 1-(isopropylideneamino)-3-phenyl-isothiourea

The solubility of 1-(isopropylideneamino)-3-phenyl-isothiourea is an intriguing aspect of its chemical behavior. Understanding how this compound interacts with solvents can greatly influence its applications and effectiveness in various environments. Here are some key points regarding its solubility:

  • Polar Solvents: This compound exhibits some solubility in polar solvents such as water and ethanol due to the presence of amino groups, which can form hydrogen bonds.
  • Non-Polar Solvents: It is likely to be less soluble in non-polar solvents, since the overall structure can inhibit effective interaction with non-polar molecules.
  • Temperature Dependence: The solubility may increase with temperature, which is a common characteristic observed in many organic compounds, potentially enhancing interactions at higher energies.
  • pH Sensitivity: The solubility could also be affected by the pH of the solvent, as changes in pH can alter the protonation state of the amino group.

In summary, the solubility of 1-(isopropylideneamino)-3-phenyl-isothiourea is a complex interplay of its molecular structure and the nature of the solvent used. To quote, "The solubility phenomena intricately links molecular characteristics to environmental conditions." Understanding these aspects can drive effective use in both research and application.

Interesting facts

Interesting Facts about 1-(Isopropylideneamino)-3-phenyl-isothiourea

1-(Isopropylideneamino)-3-phenyl-isothiourea is a fascinating compound that deserves attention for its unique structure and potential applications. Here are some noteworthy points:

  • Structure and Functionality: This compound contains both isothiourea and an isopropylideneamino group, providing a rich source of chemical properties that can interact with various biological systems.
  • Biological Relevance: Isothioureas are known for their biocompatibility and have been investigated for their potential in medicinal chemistry. They often exhibit diverse biological activities, making them interesting candidates for drug development.
  • Reactivity: The specific functional groups in 1-(isopropylideneamino)-3-phenyl-isothiourea allow for unique reactivity patterns, which can be harnessed in the synthesis of more complex molecules.
  • Applications: This compound has potential applications in:
    • Pharmaceutical development
    • Organic synthesis as a building block
    • Research into anti-tumor agents or other therapeutic areas
  • Chemical Synthesis: The synthesis of isothioureas usually involves the reaction of isothiocyanates with amines, providing an interesting pathway for creating novel compounds in organic chemistry laboratories.

In conclusion, 1-(isopropylideneamino)-3-phenyl-isothiourea not only showcases diverse chemical properties but also opens avenues for research in biological applications, making it a key compound for further investigation in the fields of chemistry and biochemistry.