1-Naphthyl isothiocyanate | Solubility of Things

Identification

Molecular formula

C₁₁H₇NS

CAS number

551-06-4

IUPAC name

1-isothiocyanatonaphthalene

State

At room temperature, 1-naphthyl isothiocyanate is a solid. It is generally stable under normal conditions of use and storage.

Melting point (Celsius)

56.00

Melting point (Kelvin)

329.15

Boiling point (Celsius)

294.00

Boiling point (Kelvin)

567.15

General information

Molecular weight

185.24g/mol

Molar mass

185.2430g/mol

Density

1.1900g/cm³

Appearence

1-Naphthyl isothiocyanate is typically a pale yellow solid. Its crystalline nature makes it appear as a powder or granules. The colour can vary slightly depending on the specific impurities or handling conditions.

Comment on solubility

Solubility of 1-Isothiocyanatonaphthalene

1-Isothiocyanatonaphthalene, with the formula C₁₁H₈N₂S, exhibits *moderate solubility characteristics* in various solvents. Understanding its solubility is essential for applications in fields such as organic synthesis and materials science.

Solubility Characteristics:

In Organic Solvents: 1-Isothiocyanatonaphthalene is generally soluble in non-polar organic solvents like benzene, toluene, and chloroform.
In Water: This compound has a low solubility in water, which is characteristic of many aromatic compounds due to their hydrophobic nature.
Temperature Dependency: Solubility may increase with temperature, as is typical for many organic compounds, allowing for better dissolution in organic solvents when heated.

When discussing its solubility, it's essential to consider the following factors:

**Polarity of the Solvent:** Since 1-isothiocyanatonaphthalene has a non-polar aromatic structure, it tends to dissolve well in non-polar environments.
**Molecular Interactions:** The presence of the isothiocyanate group can engage in specific interactions, such as hydrogen bonding, which may affect its solubility in certain solvents.

As a final note, it's important to remember that while this compound is not highly soluble in water, it has significant applications in organic reactions and the development of functional materials due to its *unique chemical properties*.

Interesting facts

Interesting Facts about 1-Isothiocyanatonaphthalene

1-Isothiocyanatonaphthalene is a fascinating compound that falls within the category of isothiocyanates, which are known for their diverse applications in the fields of chemistry and biology. Here are some intriguing aspects of this compound:

Chemical Structure: As a derivative of naphthalene, 1-isothiocyanatonaphthalene features a distinct functional group—the isothiocyanate group. This structural uniqueness contributes to its chemical reactivity and potential applications in synthesis.
Biological Activity: Isothiocyanates have been studied for their biological effects, including anticancer properties. Research highlights their potential in modulating cellular pathways and combating various types of cancer.
Natural Occurrence: Compounds like 1-isothiocyanatonaphthalene can be found in cruciferous vegetables, which are renowned for their health benefits due to the presence of these isothiocyanates.
Environmental Significance: Isothiocyanates also play a role in plant defense mechanisms against pests and pathogens, thus contributing to ecological balance and sustainable agriculture practices.
Research Applications: In synthetic chemistry, 1-isothiocyanatonaphthalene serves as an important intermediate in the synthesis of various organic compounds, making it a valuable building block in pharmaceutical and materials science.

In conclusion, the study of 1-isothiocyanatonaphthalene offers a window into the relevance of isothiocyanates in both nature and human innovation. As we delve deeper into its properties and applications, it becomes clear that this compound is more than just a simple molecule—it is a potential key in the quest for new biochemical solutions.

Synonyms

1-Naphthyl isothiocyanate

551-06-4

1-Naphthylisothiocyanate

1-ISOTHIOCYANATONAPHTHALENE

Kesscocide

alpha-Naphthyl isothiocyanate

Naphthalene, 1-isothiocyanato-

1-Naftylisothiokyanat

alpha-Naphthysothiocyanate

NSC 89741

1-Naftylisothiokyanat [Czech]

CCRIS 4678

CHEBI:35455

alpha-Naphthylisothiocyanate

EINECS 208-990-8

BRN 0637868

AI3-28260

HG44814A3V

NSC-89741

4-12-00-03094 (Beilstein Handbook Reference)

NAPHTHYL ISOTHIOCYANATE, 1-

1-NAPHTHYLISOTHIOCYANATE [MI]

1 Naphthylisothiocyanate

alpha Naphthylisothiocyanate

1Naftylisothiokyanat

1Naphthyl isothiocyanate

alphaNaphthyl mustard oil

1Isothiocyanatenaphthalene

1Isothiocyanatonaphthalene

alphanaphthylisothiocyanate

Naphthalene, isothiocyanato

alphaNaphthyl isothiocyanate

Naphthalene, 1isothiocyanato

ALPHA-NAPHTHYL MUSTARD OIL

1Naphthyl ester isothiocyanic acid

Isothiocyanic acid, 1naphthyl ester

1-NAPHTHYL ESTER ISOTHIOCYANIC ACID

208-990-8

ANIT

Isothiocyanatonaphthalene

Naphthalene, isothiocyanato-

Isothiocyanic acid, 1-naphthyl ester

29962-76-3

alpha-naphylisothiocyanate

EINECS 249-976-1

1-Isothiocyanatenaphthalene

.alpha.-Naphthysothiocyanate

.alpha.-Naphthyl isothiocyanate

ANI

DTXSID8025703

Isothiocyanic Acid 1-Naphthyl Ester

1-Isothiocyanate-naphthalene

MFCD00003882

UNII-HG44814A3V

1-naphtylisothiocyanate

a-naphthylisothiocyanate

(1-naphthyl)isothiocyanate

|A-Naphthyl isothiocyanate

1-naphthalenylisothiocyanate

WLN: L66J BNCS

1-isothiocyanato-naphthalene

1-Naphthalene isothiocyanate

.alpha.-Naphthylisothiocyanate

SCHEMBL419795

DTXCID105703

CHEMBL1381098

1-Naphthyl isothiocyanate, 95%

NSC89741

Tox21_200329

BBL012567

BDBM50237618

STK300021

AKOS000212299

FN09063

NCGC00091213-01

NCGC00091213-02

NCGC00091213-03

NCGC00257883-01

BP-11139

CAS-551-06-4

PD074994

VS-03391

DB-019293

I0190

NS00033239

EN300-18199

D91098

A830490

Q4545797

Z57358335

1-Naphthyl isothiocyanate, for HPLC derivatization, >=98.5% (HPLC and GC)