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p-Cresol methyl ether

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Identification
Molecular formula
C8H10O
CAS number
104-93-8
IUPAC name
1-methoxy-4-methyl-benzene
State
State

At room temperature, p-Cresol methyl ether is in the liquid state. It is often used as a solvent or a chemical intermediate due to its properties.

Melting point (Celsius)
-29.50
Melting point (Kelvin)
243.65
Boiling point (Celsius)
172.30
Boiling point (Kelvin)
445.45
General information
Molecular weight
122.17g/mol
Molar mass
122.1650g/mol
Density
0.9650g/cm3
Appearence

p-Cresol methyl ether is a clear liquid. It is typically colorless, but can appear slightly yellowish when impurities are present. It has a characteristic aromatic odor that is typical of aromatic compounds.

Comment on solubility

Solubility of 1-methoxy-4-methyl-benzene

1-methoxy-4-methyl-benzene, commonly known as p-anisole, exhibits notable solubility characteristics that are of interest in various chemical applications. The molecule's structure consists of a benzene ring substituted with both a methoxy group (-OCH3) and a methyl group (-CH3), influencing its interaction with solvents.

Key points regarding the solubility of 1-methoxy-4-methyl-benzene include:

  • Solvent Compatibility: p-anisole is primarily soluble in organic solvents such as ethanol, ether, and benzene, owing to its non-polar characteristics.
  • Polar vs Non-Polar: It has limited solubility in polar solvents like water, as the significant hydrophobic (water-repelling) nature of the benzene ring dominates its behavior.
  • Intermolecular Forces: The presence of the methoxy group allows for some degree of hydrogen bonding with polar solvents, yet this is typically insufficient to enhance its overall solubility in water.

In summary, while 1-methoxy-4-methyl-benzene is predominantly soluble in non-polar and moderately polar organic solvents, its solubility in water remains minimal. This characteristic can be crucial when considering p-anisole's application in synthesis and extraction processes, where solvent selection is vital for optimal performance.

Interesting facts

Interesting Facts about 1-Methoxy-4-methyl-benzene

1-Methoxy-4-methyl-benzene, commonly known as p-anisole, is a fascinating compound with a variety of applications and characteristics. Here are some points to consider:

  • Nature and Structure: As an aromatic ether, 1-methoxy-4-methyl-benzene consists of a benzene ring substituted with a methoxy group (-OCH3) and a methyl group (-CH3). This unique structure contributes to its chemical reactivity and solubility.
  • Industrial Applications: The compound is widely used as a solvent in organic synthesis and as a flavoring agent in the food industry due to its pleasant anise-like aroma.
  • Research Significance: Scientists often utilize p-anisole as a model compound in the study of reaction mechanisms involving ethers and phenolic compounds.
  • Biological Activity: Some studies have suggested that 1-methoxy-4-methyl-benzene may exhibit antimicrobial properties, making it a subject of interest in the field of medicinal chemistry.
  • Versatile Synthesis: It can be synthesized through several methods, including the methylation of phenol, highlighting the versatility of organic synthesis techniques.

As you can see, 1-methoxy-4-methyl-benzene is not just another simple organic compound; it plays a significant role in various fields, from industrial applications to academic research. Its unique properties and structure open the door to exciting possibilities in chemistry!

Synonyms
4-Methylanisole
1-METHOXY-4-METHYLBENZENE
104-93-8
p-Methylanisole
4-Methoxytoluene
p-Methoxytoluene
Benzene, 1-methoxy-4-methyl-
p-Cresol methyl ether
p-Cresyl methyl ether
p-methyl anisole
Anisole, p-methyl-
4-Methyl anisole
Methyl p-cresol
Methyl p-tolyl ether
p-Tolyl methyl ether
para-Methylanisole
Methyl p-cresyl ether
1-Methyl-4-methoxybenzene
4-Methyl-1-methoxybenzene
4-Methylphenol methyl ether
Methyl 4-methylphenyl ether
Methyl-para-cresol
para-Methoxytoluene
Methyl p-methylphenyl ether
para-Cresyl methyl ether
p-methylanisol
Toluene, 4-methoxy-
FEMA No. 2681
FEMA Number 2681
para-methyl anisole
1-Methoxy-4-methyl-benzene
NSC 6254
HSDB 5363
4-Methylanizole
EINECS 203-253-7
para-Methyl anisol
10FAI0OR9W
4-methylmethoxybenzene
DTXSID9026710
AI3-07621
NSC-6254
4-CRESOL METHYL ETHER
P-METHYLANISOLE [FHFI]
CHEMBL154155
DTXCID306710
P-METHYL ANISOLE [FCC]
CHEBI:89728
EC 203-253-7
1-METHOXY-4-METHYLBENZENE [HSDB]
4-methylanisol
PARA-CRESOL DEUTEROMETHYL ETHER
MFCD00008413
UNII-10FAI0OR9W
pMethoxytoluene
pMethylanisole
4Methoxytoluene
Methylparacresol
Methyl pcresol
paraMethylanisole
4Methyl anisole
p- methylanisole
Anisole, pmethyl
paraMethoxytoluene
p-Methyl-Anisole
p-Methoxy toluene
4-methoxy-toluene
Toluene, 4methoxy
Methyl ptolyl ether
pTolyl methyl ether
Methyl pcresyl ether
pCresol methyl ether
pCresyl methyl ether
1Methyl4methoxybenzene
4Methyl1methoxybenzene
paraCresyl methyl ether
4-Methylanisole (MSO)
P- METHOXYTOLUENE
4-Methylanisole, 99%
Benzene, 1methoxy4methyl
Methyl pmethylphenyl ether
4Methylphenol methyl ether
Methyl 4methylphenyl ether
1-methyoxy-4-methylbenzene
SCHEMBL12464
WLN: 1OR D1
SCHEMBL2489775
SCHEMBL12015216
FEMA 2681
NSC6254
LRB43136
4-Methylanisole, analytical standard
Tox21_201081
BDBM50008555
STL268886
AKOS000121016
4-Methylanisole, >=99%, FCC, FG
CS-W013551
HY-W012835
NCGC00248917-01
NCGC00258634-01
BS-23266
CAS-104-93-8
PD164982
M0149
NS00010202
EN300-16112
Q15726084
Z53834227
F0001-0094