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Nitrofurazone

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Identification
Molecular formula
C6H6N4O4
CAS number
59-87-0
IUPAC name
1-methyl-1-[(5-nitro-2-furyl)methyleneamino]urea
State
State

Nitrofurazone is typically a solid at room temperature, characterized by its crystalline powder form.

Melting point (Celsius)
236.00
Melting point (Kelvin)
509.15
Boiling point (Celsius)
350.00
Boiling point (Kelvin)
623.15
General information
Molecular weight
198.14g/mol
Molar mass
198.1400g/mol
Density
1.7480g/cm3
Appearence

Nitrofurazone appears as a yellow, crystalline powder. The vibrant color is due to the presence of the nitro group attached to the furan ring, giving it its characteristic yellow hue.

Comment on solubility

Solubility of 1-methyl-1-[(5-nitro-2-furyl)methyleneamino]urea

The solubility of 1-methyl-1-[(5-nitro-2-furyl)methyleneamino]urea is a critical property that influences its application in various chemical processes. This compound exhibits specific solubility characteristics that are essential to consider:

  • Solvent Compatibility: 1-methyl-1-[(5-nitro-2-furyl)methyleneamino]urea tends to be soluble in organic solvents such as dimethyl sulfoxide (DMSO) and dimethylformamide (DMF). However, it shows limited solubility in water, which is a common trait for many organic compounds with nitro and urea functional groups.
  • Temperature Influence: The solubility of this compound may increase at elevated temperatures, making it more amenable for reactions requiring high temperatures in organic synthesis.
  • pH Dependency: The solubility can also vary significantly with changes in pH, particularly due to the nature of the urea group. An alkaline environment may enhance solubility while an acidic environment could lead to precipitation.

As one navigates through the applications of 1-methyl-1-[(5-nitro-2-furyl)methyleneamino]urea, understanding its solubility is vital. To quote a well-known principle in chemistry, “Like dissolves like,” which underscores the importance of matching the polarity of solvents to optimize solubility.

Overall, exploring the solubility profile of this compound can lead to improved practical utilization in chemical reactions and formulations.

Interesting facts

Interesting Facts about 1-methyl-1-[(5-nitro-2-furyl)methyleneamino]urea

1-methyl-1-[(5-nitro-2-furyl)methyleneamino]urea is a fascinating compound that draws attention not only for its structural complexity but also for its potential applications in various fields. Here are some key insights:

  • Biological Significance: This compound exhibits potential pharmacological properties, particularly in the realm of medicinal chemistry. Its nitro group can be pivotal in enhancing biological activity, making it a subject of interest in drug design.
  • Antimicrobial Properties: Research has suggested that derivatives of nitrofuran compounds, including this one, may possess antimicrobial properties, which could be beneficial in combating resistant strains of bacteria.
  • Structure-Activity Relationship (SAR): The unique combination of the 5-nitro-2-furyl group with the urea framework allows chemists to explore various modifications. Understanding the SAR can lead to the development of more effective compounds with targeted actions.
  • Environmental Implications: Due to its structural attributes, 1-methyl-1-[(5-nitro-2-furyl)methyleneamino]urea could be studied for environmental impacts, especially concerning its degradation pathways and persistence in ecosystems.
  • Research Pathways: Ongoing research may uncover new pathways for synthesizing this compound, opening up avenues for more sustainable production methods that are environmentally friendly.

In summary, 1-methyl-1-[(5-nitro-2-furyl)methyleneamino]urea represents a rich area for research, with its implications spanning medicinal chemistry to environmental science. As Dr. Marie Curie famously stated, "Nothing in life is to be feared; it is only to be understood." Understanding compounds like this one can pave the way for innovations that benefit society.