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Zolpidem

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Identification
Molecular formula
C9H14N2O2
CAS number
82626-48-0
IUPAC name
1-methyl-1,3-diazaspiro[4.5]decane-2,4-dione
State
State

At room temperature, Zolpidem is a solid. It is typically formulated into tablets or other forms for oral administration in the treatment of insomnia.

Melting point (Celsius)
196.00
Melting point (Kelvin)
469.15
Boiling point (Celsius)
386.00
Boiling point (Kelvin)
659.15
General information
Molecular weight
219.26g/mol
Molar mass
219.2600g/mol
Density
1.3000g/cm3
Appearence

Zolpidem typically appears as a white to off-white crystalline powder, and it is often available in tablet form for medicinal use. The powder itself is odorless.

Comment on solubility

Solubility of 1-methyl-1,3-diazaspiro[4.5]decane-2,4-dione

The solubility of 1-methyl-1,3-diazaspiro[4.5]decane-2,4-dione can be characterized by a few key points:

  • Polar nature: Due to the presence of nitrogen atoms and carbonyl groups in its structure, this compound is likely to exhibit moderate solubility in polar solvents such as water and alcohols.
  • Non-polar solvents: It may exhibit lower solubility in non-polar solvents like hexane or toluene due to the overall polarity of its functional groups.
  • Hydrogen bonding: The ability to form hydrogen bonds contributes significantly to its interaction with polar solvents, enhancing its solubility profile.

Overall, while specific solubility data for 1-methyl-1,3-diazaspiro[4.5]decane-2,4-dione may be limited, we can anticipate its solubility behavior to be influenced by its molecular structure and the solvent characteristics:

  1. Experimentally determined solubility in aqueous solutions is expected to vary.
  2. Solubility in organic solvents may provide insights into its uses in chemical reactions and formulations.

As always, it is important to conduct empirical tests to precisely ascertain the solubility characteristics of this compound, as theoretical predictions can vary.

Interesting facts

Interesting Facts About 1-Methyl-1,3-Diazaspiro[4.5]decane-2,4-dione

The compound 1-methyl-1,3-diazaspiro[4.5]decane-2,4-dione is a fascinating example of a spirocyclic structure in organic chemistry. Spiro compounds are characterized by two or more rings sharing a single atom, which contributes to their unique chemical properties and reactivity. Here are some intriguing aspects of this compound:

  • Structural Intricacies: The spiro structure provides a three-dimensional arrangement that can influence how the molecule interacts with other chemicals. The presence of multiple functional groups enhances its versatility in chemical reactions.
  • Biological Relevance: Compounds with a similar framework have been investigated for their potential biological activities, including antimicrobial and anticancer properties. Research into spiro compounds can reveal new therapeutic agents.
  • Synthetic Pathways: The synthesis of 1-methyl-1,3-diazaspiro[4.5]decane-2,4-dione illustrates the creativity of synthetic organic chemists. Various synthetic routes can lead to this compound, involving intriguing reactions that can further broaden the understanding of spiro compounds.
  • Applications in Material Science: The unique physical properties of spirocyclic compounds can make them suitable for applications in material science, particularly in the development of novel polymers and nanomaterials.

In conclusion, 1-methyl-1,3-diazaspiro[4.5]decane-2,4-dione showcases the intersection of structure, reactivity, and potential applications that make spiro compounds a subject of ongoing interest in both academic and industrial research.

Synonyms
1-Methyl-1,3-diazaspiro[4.5]decane-2,4-dione
878-46-6
1'-Methylcyclohexanespiro-5'-hydantoin
BRN 0168127
1,3-DIAZASPIRO(4.5)DECANE-2,4-DIONE, 1-METHYL-
DTXSID20236647
1,3-Diazaspiro[4.5]decane-2,4-dione, 1-methyl-
1-methyl-1,3-diazaspiro(4.5)decane-2,4-dione
DTXCID50159138
837-001-8
1,3-Diazaspiro[4.5]decane-2,4-dione,1-methyl-
MFCD01731589
BVGOFWCNHZHTHW-UHFFFAOYSA-N
AAA87846
AKOS002683188
CCG-344336
BS-36056
CS-0229991
EN300-10184
1-Methyl-1,3-diazaspiro[4.5]decane-2,4-dione #
Z56998600
F1967-0970