Skip to main content

Trimethoprim

ADVERTISEMENT
Identification
Molecular formula
C14H18ClN3O3
CAS number
738-70-5
IUPAC name
[[1-methyl-2-(3,4,5-trimethoxyphenyl)ethyl]amino]ammonium;chloride
State
State

At room temperature, trimethoprim is typically in a solid state as a crystalline powder.

Melting point (Celsius)
199.00
Melting point (Kelvin)
472.15
Boiling point (Celsius)
357.40
Boiling point (Kelvin)
630.60
General information
Molecular weight
290.32g/mol
Molar mass
290.3210g/mol
Density
1.0820g/cm3
Appearence

Trimethoprim appears as a white to yellowish-white, crystalline powder. It is odorless and slightly bitter in taste. In its pure form, it is characterized by uniformity in texture and color.

Comment on solubility

Solubility of [1-methyl-2-(3,4,5-trimethoxyphenyl)ethyl]aminoammonium chloride

The solubility of [1-methyl-2-(3,4,5-trimethoxyphenyl)ethyl]aminoammonium chloride can be analyzed considering several factors.

Factors Influencing Solubility:

  • Polarity: The presence of polar groups in the molecule, such as the ammonium ion and chlorine, suggests a potential for solubility in polar solvents like water.
  • Functional Groups: The trimethoxyphenyl structure may enhance solubility due to its ability to participate in hydrogen bonding.
  • Temperature Effects: Generally, increased temperature may raise solubility, but the specific temperature dependence for this compound needs to be empirically determined.

Overall, hydrophilicity contributed by the charged ammonium and the chloride ion indicates this compound may demonstrate considerable solubility in aqueous solutions, particularly at elevated temperatures. However, final solubility details should be confirmed through experimental data as specific molecular interactions might alter expected behavior.

Interesting facts

Interesting Facts about [1-methyl-2-(3,4,5-trimethoxyphenyl)ethyl]aminoammonium Chloride

This compound, commonly referred to as a quaternary ammonium salt, presents a unique structure that makes it particularly intriguing for various applications in the field of chemistry.

Structural Insights

The structure of [1-methyl-2-(3,4,5-trimethoxyphenyl)ethyl]aminoammonium chloride includes several notable features:

  • Quaternary Ammonium Ion: The compound contains a positively charged nitrogen atom, which plays a crucial role in its reactivity and solubility characteristics.
  • Trimethoxyphenyl Group: The presence of the 3,4,5-trimethoxyphenyl group contributes to the compound's electronic properties, affecting its interaction with other molecules.
  • Amine Functional Group: The amino group enhances the potential for hydrogen bonding and can act as a ligand in coordination complexes.

Applications in Research and Industry

This compound is noteworthy due to its potential applications, which may include:

  • Biological Studies: Its structural features make it a candidate for research into pharmacological effects and drug design.
  • Chemical Synthesis: Possibly serving as a reagent or catalyst in organic synthesis processes.
  • Material Science: Investigation into its properties could reveal uses in developing novel materials, such as surfactants or polymers.

Potential Biological Activity

The combination of a nitrogen-rich moiety with the aromatic substituent opens avenues for testing biological activities:

  • Studies suggest that quaternary ammonium compounds may exhibit antimicrobial properties.
  • Investigations into interaction with neurotransmitter systems are also of interest, given the amino component.

In conclusion, [1-methyl-2-(3,4,5-trimethoxyphenyl)ethyl]aminoammonium chloride is not just another compound; it represents a fascinating blend of structure and potential. Its diverse implications warrant further study, making it a valuable target for scientists eager to explore the realms of chemistry and biology.

Synonyms
USAF LA-8
16603-11-5
1-(3',4',5'-Trimethoxyphenyl)-2-hydrazinopropane hydrochloride
HYDRAZINE, 1-(alpha-METHYL-3,4,5-TRIMETHOXYPHENETHYL)-, HYDROCHLORIDE