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1-methyl-2-nitroimidazole

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Identification
Molecular formula
C4H5N3O2
CAS number
3034-38-6
IUPAC name
1-methyl-2-nitro-imidazole
State
State

At room temperature, 1-methyl-2-nitroimidazole is in a solid state, often appearing as small yellow crystalline formations.

Melting point (Celsius)
190.00
Melting point (Kelvin)
463.15
Boiling point (Celsius)
329.30
Boiling point (Kelvin)
602.45
General information
Molecular weight
129.10g/mol
Molar mass
129.1100g/mol
Density
1.3594g/cm3
Appearence

1-Methyl-2-nitroimidazole is typically a solid compound at room temperature. It appears as a crystalline powder with a distinct yellow color, characteristic of many nitro compounds.

Comment on solubility

Solubility of 1-methyl-2-nitro-imidazole

1-methyl-2-nitro-imidazole is a chemical compound that exhibits unique solubility characteristics, primarily influenced by its molecular structure. Understanding its solubility can be key in various applications, ranging from pharmaceuticals to chemical synthesis.

Solubility Characteristics

  • Polarity: The presence of both the methyl and nitro groups contributes to the compound's overall polarity, affecting its interactions with solvents.
  • Solvent Dependency: 1-methyl-2-nitro-imidazole is generally soluble in polar solvents such as water and ethanol, while exhibiting limited solubility in nonpolar solvents.
  • Temperature Effects: As with many organic compounds, solubility may increase with temperature; thus, higher temperatures can enhance the dissolution process.
  • pH Influence: The solubility can also be affected by the pH of the solution, as protonation states of the imidazole ring can alter solubility behavior.

It's essential to note that “like dissolves like” typically applies; hence, the polar nature of 1-methyl-2-nitro-imidazole makes it more compatible with polar solvents. This understanding is crucial when selecting appropriate solvents for experiments or formulations involving this compound.

Interesting facts

Interesting Facts about 1-Methyl-2-Nitro-Imidazole

1-Methyl-2-nitro-imidazole is a fascinating compound with various applications in chemical research and industry. Here are some compelling insights about this unique compound:

  • Chemical Structure: The compound features an imidazole ring, which is a key structure in many biologically active molecules. The presence of both the methyl and nitro groups contributes to its reactivity and applications.
  • Biological Activity: Compounds containing imidazole rings often exhibit significant biological activity. 1-Methyl-2-nitro-imidazole has been studied for its potential as an antimicrobial agent and may play a role in drug development.
  • Research Applications: This compound is useful in various fields of research, particularly in medicinal chemistry and the synthesis of complex organic molecules. Its derivatives are used to develop pharmaceuticals that target specific diseases.
  • Prodrug Potential: Given its structure, researchers are exploring the potential of 1-methyl-2-nitro-imidazole as a prodrug, where the compound can be converted into an active drug form within the body, enhancing the efficacy of treatments.
  • Environmental Impact: Understanding the behavior and degradation of nitro-containing compounds like this one is essential in environmental chemistry, where they may be involved in bioremediation processes.

In summary, the study of 1-methyl-2-nitro-imidazole not only highlights the significance of nitrogen-containing heterocycles in chemistry but also opens doors to innovative solutions in medicine and environmental science. As a chemistry student or professional, exploring the reactivity and applications of such compounds can lead to exciting discoveries and advancements.

Synonyms
1-Methyl-2-nitroimidazole
1671-82-5
1H-Imidazole, 1-methyl-2-nitro-
Imidazole, 1-methyl-2-nitro-
CCRIS 1311
NSC 307223
BRN 0607942
DTXSID30168228
DTXCID9090719
1H-Imidazole, 1-methyl-2-nitro-(9CI)
5-23-04-00471 (beilstein handbook reference)
hbminvnvqudera-uhfffaoysa-n
1-METHYL-2-NITRO-1H-IMIDAZOLE
MFCD01721434
NSC-307223
NSC307223
R74LUE6SLE
2-Nitro-1-methylimidazole
CHEMBL303522
SCHEMBL1979557
WLN: T5N CNJ A1 BNW
SCHEMBL17145913
1-Methyl-2-nitro-1H-imidazole #
KA-111
AKOS006278739
DS-4557
SR-2519
SY235546
DB-121417
CS-0131264