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Tolperisone

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Identification
Molecular formula
C16H23NO2
CAS number
728-88-1
IUPAC name
(1-methyl-2-piperidyl)methyl N-(o-tolyl)carbamate
State
State

At room temperature, tolperisone is in a solid state, usually appearing as a crystalline powder.

Melting point (Celsius)
174.00
Melting point (Kelvin)
447.15
Boiling point (Celsius)
360.00
Boiling point (Kelvin)
633.15
General information
Molecular weight
261.37g/mol
Molar mass
261.3650g/mol
Density
1.1850g/cm3
Appearence

Tolperisone appears as a white to off-white crystalline powder. It is practically odorless and has a slightly bitter taste.

Comment on solubility

Solubility of (1-methyl-2-piperidyl)methyl N-(o-tolyl)carbamate

The solubility of (1-methyl-2-piperidyl)methyl N-(o-tolyl)carbamate can be influenced by several key factors, primarily its chemical structure and the solvents used.

Factors Affecting Solubility:

  • Polarity: The presence of polar functional groups in the compound, such as the carbamate moiety, generally increases its solubility in polar solvents like water.
  • Hydrophobicity: The o-tolyl group adds a hydrophobic character, which may limit solubility in purely polar environments.
  • Temperature: Increasing temperature typically enhances solubility as kinetic energy allows for better solvation of the compound.
  • pH: The pH of the solution can affect the ionization of the carbamate group, potentially enhancing solubility in basic conditions.

As a result, while this compound may exhibit some solubility in polar aprotic solvents and organic solvents, it is important to note that its overall solubility can vary significantly depending on the choice of solvent and environmental conditions. In general, "like dissolves like," meaning that the molecular interactions are pivotal in determining how well this compound will dissolve in any given medium.

Therefore, when working with (1-methyl-2-piperidyl)methyl N-(o-tolyl)carbamate, one must consider these factors to predict its solubility behavior effectively.

Interesting facts

Interesting Facts about (1-Methyl-2-piperidyl)methyl N-(o-tolyl)carbamate

(1-Methyl-2-piperidyl)methyl N-(o-tolyl)carbamate is a fascinating compound that belongs to the category of carbamates, which are widely known for their diverse applications in various fields of chemistry and pharmacology. Here are some intriguing aspects about this compound:

  • Structure and Stability: The presence of the piperidine ring provides structural stability and contributes to the compound's unique reactivity. This bicyclic structure is often associated with biological activity.
  • Biological Relevance: Carbamate compounds are considered important in medicinal chemistry. This particular compound may exhibit properties useful in the development of pharmaceuticals, potentially acting as an enzyme inhibitor.
  • Application in Agriculture: Like many carbamates, it's worth noting that similar compounds have applications as pesticides, herbicides, and fungicides, showcasing the versatility of this functional group in agricultural sciences.
  • Research Potential: This compound is a topic of interest in research for its potential effects in neuropharmacology. As a derivative of piperidine, it may interact with neural pathways, suggesting implications for drug development.
  • Synthetic Routes: The synthesis of (1-Methyl-2-piperidyl)methyl N-(o-tolyl)carbamate can involve various methods primarily focusing on the carbamoylation process, which can be optimized for yield and efficiency.

In essence, (1-Methyl-2-piperidyl)methyl N-(o-tolyl)carbamate exemplifies the intersection of organic chemistry and pharmacognosy, standing out as a potential candidate for further studies. As quoted by renowned chemists, "The exploration of compound properties often leads to unexpected and groundbreaking discoveries."

Overall, the compound holds promise, and further investigation could unveil benefits applicable to both human health and sustainable practices.