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1-Methyl-3-(1-methylpyrrolidin-2-yl)indole

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Identification
Molecular formula
C15H18N2
CAS number
21898-19-1
IUPAC name
1-methyl-3-(1-methylpyrrolidin-2-yl)indole
State
State
This compound is typically a solid at room temperature, with a stable crystalline structure.
Melting point (Celsius)
127.50
Melting point (Kelvin)
400.65
Boiling point (Celsius)
395.20
Boiling point (Kelvin)
668.35
General information
Molecular weight
226.32g/mol
Molar mass
226.3160g/mol
Density
1.2000g/cm3
Appearence

This compound typically appears as a crystalline solid or a powder, often with a light yellow to off-white color. It is known for its distinct aromatic properties due to the indole structure.

Comment on solubility

Solubility of 1-methyl-3-(1-methylpyrrolidin-2-yl)indole

The solubility of the compound 1-methyl-3-(1-methylpyrrolidin-2-yl)indole can be quite intriguing, given its unique structure. The solubility of organic compounds is influenced by several factors, and for this specific compound, the following points are noteworthy:

  • Polarity: The presence of both the indole and pyrrolidine functional groups may introduce varying degrees of polarity, which affects how well the compound dissolves in different solvents.
  • Solvent Type: This compound is likely to exhibit better solubility in organic solvents like dichloromethane and ethanol than in water, due to its hydrophobic nature.
  • Hydrogen Bonding: The potential for hydrogen bonding between the nitrogen atoms in the pyrrolidine group and solvent molecules can enhance solubility in polar solvents, albeit to a limited extent.
  • Concentration Factors: As with many complex organic compounds, solubility might increase at higher temperatures, making it essential to consider conditions when predicting behavior in solution.

In conclusion, while the solubility of 1-methyl-3-(1-methylpyrrolidin-2-yl)indole can vary widely depending on the solvent used and external conditions, awareness of its structural features aids in predicting its solubility characteristics.

Interesting facts

Exploring 1-methyl-3-(1-methylpyrrolidin-2-yl)indole

The compound 1-methyl-3-(1-methylpyrrolidin-2-yl)indole is an intriguing member of the indole family, which is known for its diverse biological activities and applications in medicinal chemistry. Here are some fascinating facts about this compound:

  • Structural Complexity: This compound features an indole core fused with a pyrrolidine ring, showcasing its structural diversity, which can lead to unique pharmacological properties.
  • Pharmacological Potential: Indoles are often investigated for their potential roles as antidepressants, antipsychotics, and anti-inflammatory agents. Thus, 1-methyl-3-(1-methylpyrrolidin-2-yl)indole may offer interesting therapeutic possibilities.
  • Neurotransmitter Interaction: Compounds with indole structures are known to interact with various neurotransmitter systems, including serotonin and dopamine receptors, which are vital in mood regulation and psychiatric disorders.
  • Research Interest: As a derivative of both indole and pyrrolidine, researchers are keen to explore its potential effects in neuropharmacology and related fields, making it a focus of ongoing studies.
  • Natural Occurrence: Some indole-based compounds can be found in nature as constituents of various alkaloids, indicating that 1-methyl-3-(1-methylpyrrolidin-2-yl)indole might mimic or enhance naturally occurring biochemical pathways.

Overall, the study of 1-methyl-3-(1-methylpyrrolidin-2-yl)indole not only enriches our understanding of indole chemistry but also contributes to the broader field of drug development, potentially leading to novel therapeutic agents.

Synonyms
19137-61-2
1-methyl-3-(1-methylpyrrolidin-2-yl)indole
1-Methyl-3-(1-methyl-2-pyrrolidinyl)-1H-indole
BRN 0612142
1-Methyl-3-(1-methyl-2-pyrrolidinyl)indole
INDOLE, 1-METHYL-3-(1-METHYL-2-PYRROLIDINYL)-
1-methyl-3-(1-methylpyrrolidin-2-yl)-1H-indole
DTXSID40940739