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Gramine

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Identification
Molecular formula
C11H14N2
CAS number
87-52-5
IUPAC name
1-methyl-3-[2-(4-pyridyl)ethyl]indole
State
State

Gramine is typically a solid at room temperature, existing as crystalline powder.

Melting point (Celsius)
138.00
Melting point (Kelvin)
411.15
Boiling point (Celsius)
390.00
Boiling point (Kelvin)
663.15
General information
Molecular weight
198.24g/mol
Molar mass
198.2640g/mol
Density
1.1980g/cm3
Appearence

Gramine appears as a white to off-white crystalline powder. It is typically solid at room temperature and has a distinctive structure that reflects its complex aromatic nature.

Comment on solubility

Solubility of 1-methyl-3-[2-(4-pyridyl)ethyl]indole

The solubility of 1-methyl-3-[2-(4-pyridyl)ethyl]indole can be influenced by various factors, including its molecular structure and the nature of the solvent. Here are some important points to consider:

  • Polarity: This compound contains both non-polar and polar groups, which may lead to a moderate solubility in polar organic solvents.
  • Hydrogen Bonding: The presence of the pyridyl group allows for potential hydrogen bonding with solvents that can engage in these interactions, enhancing solubility in certain instances.
  • Solvent Effects: It may demonstrate better solubility in solvents such as dimethyl sulfoxide (DMSO) or ethanol, while solubility in hexane or other non-polar solvents may be limited.
  • Temperature Influence: As with many organic compounds, an increase in temperature can lead to improved solubility due to increased molecular motion.

In conclusion, the solubility of 1-methyl-3-[2-(4-pyridyl)ethyl]indole is indeed a fascinating subject, with various factors dictating its behavior in different environments. Experimentation is key to determining precise solubility values in specific solvents, which can provide valuable insights into its applications in different fields.

Interesting facts

Interesting Facts About 1-methyl-3-[2-(4-pyridyl)ethyl]indole

The compound known as 1-methyl-3-[2-(4-pyridyl)ethyl]indole is a fascinating member of the indole family. Indoles are aromatic organic compounds known for their synthesis and presence in various biological systems. Here are some intriguing facts about this specific compound:

  • Structural Complexity: The presence of both a methyl group and a pyridyl group makes this compound structurally unique. Indoles are known for their ability to form diverse structures and this particular substitution pattern enhances that diversity.
  • Biological Relevance: Many indole derivatives, such as those resembling 1-methyl-3-[2-(4-pyridyl)ethyl]indole, have been found to exhibit important pharmacological properties, including anti-cancer and anti-inflammatory activities.
  • Research Applications: This compound has potential applications in medicinal chemistry, particularly in the development of new therapeutic agents. Its structural components may lead to interactions with biological targets that could be exploited in drug design.
  • Electronic Properties: The combination of the aromatic indole core and the pyridyl group may impart interesting electronic properties, making this compound a candidate for use in organic electronics, such as organic light-emitting diodes (OLEDs).
  • Environmental Impact: Some indole derivatives have been studied for their roles as natural products in the environment. Understanding their behavior and transformation in nature can contribute to our knowledge of ecological dynamics.

In summary, 1-methyl-3-[2-(4-pyridyl)ethyl]indole is not just another chemical entity; it embodies the rich interplay of chemistry, biology, and applications that can lead to advancements in various fields. As noted by many researchers, "The beauty of chemistry lies in its complexity and the interconnectedness of chemical entities with life and technology."

Synonyms
16571-53-2
1-methyl-3-(2-pyridin-4-ylethyl)indole
1-METHYL-3-[2-(4-PYRIDYL)ETHYL]-1H-INDOLE
1-Methyl-3-(2-(4-pyridyl)ethyl)-1H-indole
EINECS 240-630-5
1-Methyl-3-(2-(4-pyridyl)ethyl)indole
1-Methyl-3-[2-(4-pyridinyl)ethyl]-1H-indole
Oprea1_710180
SCHEMBL6351593
DTXSID80168016
NS00025424
AE-473/30364014