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Nitrofurantoin

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Identification
Molecular formula
C8H6N4O5
CAS number
67-20-9
IUPAC name
[[1-methyl-3-(4-nitrophenyl)propylidene]amino]urea
State
State

Nitrofurantoin is typically found as a solid at room temperature. It is commonly used in its crystalline or powder form for pharmaceutical preparations.

Melting point (Celsius)
272.50
Melting point (Kelvin)
545.65
Boiling point (Celsius)
361.80
Boiling point (Kelvin)
634.95
General information
Molecular weight
238.16g/mol
Molar mass
238.1570g/mol
Density
1.6540g/cm3
Appearence

Nitrofurantoin appears as a yellow crystalline powder. It is often found in a microcrystalline form, which improves its solubility and bioavailability. Its powder form can vary from pale to bright yellow, and it is odorless.

Comment on solubility

Solubility of [1-methyl-3-(4-nitrophenyl)propylidene]amino]urea

The solubility of the compound [1-methyl-3-(4-nitrophenyl)propylidene]amino]urea can be influenced by several factors, including temperature, solvent polarity, and molecular interactions. In general, compounds containing urea functional groups exhibit distinctive solubility properties due to their ability to form hydrogen bonds.

Here are some aspects to consider regarding the solubility of this compound:

  • Solvent Characteristics: Compounds similar to urea often exhibit better solubility in polar solvents, such as water, due to their ability to engage in hydrogen bonding.
  • Molecular Structure: The presence of the nitrophenyl group may increase the hydrophobic character of the compound, potentially influencing its solubility in non-polar solvents.
  • Temperature Effects: Like many solids, the solubility of this compound may increase with rising temperatures, which typically dissolves solids more effectively.

As a result, predicting the precise solubility might require experimental data. The compound may exhibit moderate solubility in a variety of solvents, but its behavior in specific applications should be evaluated to determine optimal use.

Interesting facts

Interesting Facts about [1-methyl-3-(4-nitrophenyl)propylidene]amino]urea

[1-methyl-3-(4-nitrophenyl)propylidene]amino]urea is a remarkable compound with unique properties and applications. This compound is notable for its diverse potential in chemistry and industry.

Chemical Structure and Properties

It features a complex structure incorporating both an amino group and a nitrophenyl group, which contributes significantly to its chemical reactivity. The presence of the nitro group often enhances the compound's electrophilic character, making it an interesting substrate for various chemical reactions.

Applications

  • Pharmaceutical Research: Compounds like this are often investigated for their potential in drug development due to their biological activity.
  • Dyes and Pigments: The vibrant colors associated with nitrophenyl derivatives make them suitable for use in dyes and pigments.
  • Agricultural Chemistry: Investigations into the herbicidal and pesticidal properties of related structures are ongoing, showcasing the compound's potential in agriculture.

Significance in Chemistry

This compound showcases the fascinating concept of structural isomerism. The specific arrangement of atoms and the different functional groups can lead to differing chemical properties and reactions. As noted in one study, "the interaction of amino groups with electrophilic centers often boosts the reactivity of the compound, paving the way for innovative synthetic pathways."

Research Directions

Ongoing research is aimed at exploring:

  • Optimization of synthesis methods for enhanced yields.
  • Investigation of biological activity and mechanisms of action.
  • Exploration of potential applications in nanotechnology and materials science.

In conclusion, [1-methyl-3-(4-nitrophenyl)propylidene]amino]urea is not just a compound with intriguing structural features but also a gateway to a variety of applications in modern chemistry and industry. Its importance underscores the significance of studying complex organic compounds for future innovations.