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Nitrofurazone

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Identification
Molecular formula
C6H6N4O4
CAS number
59-87-0
IUPAC name
1-methyl-3-[(5-nitro-2-furyl)methyleneamino]urea
State
State

Nitrofurazone is typically in a solid state at room temperature. It is used as a topical antibacterial and is often found in powders or combined with water or other solvents for use.

Melting point (Celsius)
236.00
Melting point (Kelvin)
509.15
Boiling point (Celsius)
345.00
Boiling point (Kelvin)
618.15
General information
Molecular weight
198.14g/mol
Molar mass
198.1400g/mol
Density
1.6770g/cm3
Appearence

Nitrofurazone appears as a yellow, crystalline solid. It is known for its distinctive bright yellow color and crystalline form, often seen in powdered or granular format.

Comment on solubility

Solubility of 1-methyl-3-[(5-nitro-2-furyl)methyleneamino]urea

The solubility of 1-methyl-3-[(5-nitro-2-furyl)methyleneamino]urea can be described as follows:

  • Polar Nature: Due to the presence of nitro and amino functional groups, this compound exhibits polar characteristics which can enhance its solubility in polar solvents.
  • Solvent Compatibility: This compound is more likely to dissolve in solvents such as:
    • Water
    • Alcohols
    • Dimethyl sulfoxide (DMSO)
  • Limited Solubility: Despite its polar nature, the overall solubility may still be limited in certain environments, especially in non-polar solvents.
  • Temperature Influence: Solubility may also vary with temperature, where increased temperature generally enhances solubility for many compounds.

In essence, while 1-methyl-3-[(5-nitro-2-furyl)methyleneamino]urea can be expected to have reasonable solubility in specific polar solvents, it may face challenges in non-polar environments. Therefore, understanding the solubility behavior of this compound is crucial for its potential applications in various chemical processes.

Interesting facts

Interesting Facts about 1-Methyl-3-[(5-nitro-2-furyl)methyleneamino]urea

1-Methyl-3-[(5-nitro-2-furyl)methyleneamino]urea is a fascinating compound that has attracted attention in various fields of chemistry and biochemistry. Here are some intriguing aspects of this compound:

  • Origin: This compound is derived from urea, a well-known nitrogen-containing compound. Its modification with a furyl group significantly alters its chemical properties and reactivity.
  • Biological Activity: 1-Methyl-3-[(5-nitro-2-furyl)methyleneamino]urea has shown potential as a pharmacological agent due to its nitro group, which can participate in reduction reactions in biological systems.
  • Applications: The unique structure of this compound makes it a valuable candidate in medicinal chemistry. It has been studied for potential applications in anti-cancer therapies and as an antimicrobial agent.
  • Importance of the Furyl Group: The inclusion of a furyl group is significant. It enhances the lipophilicity of the compound, potentially improving its bioavailability and efficacy.
  • Synthesis: The synthesis of this compound often involves multistep reactions, showcasing the intricate techniques used in organic synthesis, such as condensation reactions and functional group transformations.
  • Research Opportunities: Ongoing research continues to explore its mechanisms of action and potential derivatives that could lead to more effective compounds based on its structure.

As one of the compounds within the broader category of substituted ureas, its study illustrates the endless possibilities of chemical modifications and their impacts on biological functionality. As a chemistry student or scientist, you may find this compound's unique attributes inspiring and a gateway to exploring more complex structures in the realm of medicinal chemistry.