Interesting facts
Interesting Facts about 1-Methyl-3-[[methyl(nitroso)carbamoyl]amino]-1-nitroso-urea
This compound, commonly known as a nitrosourea, is part of a class of chemicals that are particularly significant in the field of medicinal chemistry and cancer treatment. Here are some engaging facts about it:
- Cancer Treatment Pioneer: Nitrosoureas have been instrumental in cancer therapy. They were among the first chemotherapeutic agents used to treat a range of tumors, particularly brain cancers and lymphomas.
- Mechanism of Action: This compound functions through the process of alkylation, which involves adding alkyl groups to DNA. This process can lead to DNA cross-linking, preventing DNA replication and ultimately triggering cell death.
- Biochemical Properties: The presence of nitrogen and oxygen in its structure contributes to its reactivity and biological efficacy. The nitroso group is particularly notable for its potential to form reactive intermediates.
- Research Applications: In addition to therapeutic uses, 1-methyl-3-[[methyl(nitroso)carbamoyl]amino]-1-nitroso-urea is also used in laboratory settings to study the mechanisms of DNA repair and mutagenesis.
- Development of Resistance: One of the challenges faced in cancer treatment with nitrosoureas is the development of drug resistance. Studying the pathways through which resistance occurs is a dynamic field of research.
Overall, 1-methyl-3-[[methyl(nitroso)carbamoyl]amino]-1-nitroso-urea not only holds a significant place in the history of chemotherapeutics but also continues to inspire new research aimed at improving treatment protocols for cancer patients.
Synonyms
Biurea, 1,6-dimethyl-1,6-dinitroso-
3844-60-8
SRI 1666
Hydroazodicarboxybis(methylnitrosamide)
Hydrazodicarboxylic acid bis(methylnitrosamide)
4YY9ENV92G
Hydrazodicarbonsaeureabis(methylnitrosamid)
1,2-Hydrazinedicarboxamide, N,N'-dimethyl-N,N'-dinitroso-
1,6-Dimethyl-1,6-dinitroso-biurea
NSC-409425
1,6-DIMETHYL-1,6-DINITROSOBIUREA
NSC 409425
BRN 2125382
Hydrazodicarbonsaeureabis(methylnitrosamid) [German]
1,6-dinitrosobiurea
UNII-4YY9ENV92G
WLN: ONN1&VMMVN1&NO
CHEMBL1984448
DTXSID20191762
Biurea,6-dimethyl-1,6-dinitroso-
NSC409425
NCI60_003926
N1,N2-DIMETHYL-N1,N2-DINITROSO-1,2-HYDRAZINEDICARBOXAMIDE
Solubility of 1-methyl-3-[[methyl(nitroso)carbamoyl]amino]-1-nitroso-urea
The solubility of 1-methyl-3-[[methyl(nitroso)carbamoyl]amino]-1-nitroso-urea can be characterized through various factors that influence its behavior in different solvents.
Moreover, it is essential to remember that the presence of substituents like the nitroso and carbamoyl groups can significantly alter the overall solubility profile. As with many compounds, a combination of factors will ultimately dictate how well 1-methyl-3-[[methyl(nitroso)carbamoyl]amino]-1-nitroso-urea can be dissolved in various mediums. Always make sure to consult specific solubility data for precise applications.