Skip to main content

Coluracetam

ADVERTISEMENT
Identification
Molecular formula
C19H23NO3
CAS number
135463-81-9
IUPAC name
(1-methyl-3-morpholino-propyl) 4-phenyltetrahydropyran-4-carboxylate
State
State

Coluracetam is in solid state at room temperature and is generally found in powdered form.

Melting point (Celsius)
148.00
Melting point (Kelvin)
421.15
Boiling point (Celsius)
625.00
Boiling point (Kelvin)
898.15
General information
Molecular weight
341.44g/mol
Molar mass
341.4420g/mol
Density
1.2230g/cm3
Appearence

Coluracetam is typically found as a white to off-white crystalline powder. It is not very soluble in water, but soluble in organic solvents.

Comment on solubility

Solubility of (1-methyl-3-morpholino-propyl) 4-phenyltetrahydropyran-4-carboxylate

The solubility of (1-methyl-3-morpholino-propyl) 4-phenyltetrahydropyran-4-carboxylate can be influenced by several factors, including its structure and the solvent characteristics. Generally speaking, this compound is expected to exhibit partial solubility in polar solvents due to the presence of the morpholine group, which can engage in hydrogen bonding. Here are some key points regarding its solubility:

  • Polarity: The morpholino moiety contributes to the polar nature of the compound, potentially enhancing solubility in water.
  • Protonation: The basic nitrogen in the morpholine ring can lead to increased solubility under acidic conditions.
  • Alkyl chain influence: The hydrophobic propyl group may reduce solubility in highly polar solvents, providing an interesting balance to the solubility profile.
  • Solvent Compatibility: This compound is anticipated to show greater solubility in organic solvents such as ethanol and dimethyl sulfoxide (DMSO).

In conclusion, while solubility may vary depending on environmental conditions, it can be summarized that (1-methyl-3-morpholino-propyl) 4-phenyltetrahydropyran-4-carboxylate is likely to be more soluble in polar organic solvents and somewhat soluble in water, influenced strongly by the compound's structural features and external conditions.

Interesting facts

Interesting Facts about (1-methyl-3-morpholino-propyl) 4-phenyltetrahydropyran-4-carboxylate

(1-methyl-3-morpholino-propyl) 4-phenyltetrahydropyran-4-carboxylate, a fascinating compound often explored in organic synthesis and medicinal chemistry, has a number of intriguing features:

  • Complex Structure: This compound embodies a unique molecular architecture, combining a morpholine group with a tetrahydropyran moiety and an esters structure, making it a point of interest for researchers focusing on structure-activity relationships.
  • Potential Applications: It holds promise in pharmaceutical applications, particularly as a precursor or intermediate for synthesizing other bioactive compounds. Its structural attributes may influence pharmacokinetic and pharmacodynamic properties.
  • Research Significance: The morpholino ring contributes to unique electron-donating characteristics, which may affect the reactivity and stability of related compounds, allowing insight into various reaction mechanisms.
  • Significant Derivatives: Investigating derivatives of this compound might yield new materials with enhanced functionality or selective properties tailored for specific applications, such as drug delivery systems or advanced materials.
  • Industrial Importance: Compounds similar to this one are increasingly recognized in the field of agrochemicals and fine chemicals, showcasing versatility in diverse applications.

As we explore and unravel the complexities of (1-methyl-3-morpholino-propyl) 4-phenyltetrahydropyran-4-carboxylate, it exemplifies how the intricacies of molecular design can lead to profound advancements in chemical research and industrial development.

Synonyms
Fedrilate
23271-74-1
Fedrilato
Fedrilatum
Gotas binelli
Fedrilato [INN-Spanish]
UCB 3928
Fedrilate [INN:DCF]
Fedrilatum [INN-Latin]
UCB-3928
UNII-NT86R8M7J5
Fedrilate (INN)
NT86R8M7J5
Gotas binelli (TN)
FEDRILATE [INN]
EINECS 245-545-7
FEDRILATE [MART.]
FEDRILATE [WHO-DD]
Fedrilatum (INN-Latin)
Fedrilato (INN-Spanish)
1-Methyl-3-morpholinopropyl tetrahydro-4-phenyl-2H-pyran-4-carboxylate
FEDRILATE (MART.)
2H-Pyran-4-carboxylic acid, tetrahydro-4-phenyl-, 1-methyl-3-morpholinopropyl ester
4-(Morpholin-4-yl)butan-2-yl 4-phenyloxane-4-carboxylate
2H-PYRAN-4-CARBOXYLIC ACID, TETRAHYDRO-4-PHENYL-, 1-METHYL-3-(4-MORPHOLINYL)PROPYL ESTER
4-MORPHOLINEPROPANOL, .ALPHA.-METHYL-, TETRAHYDRO-4-PHENYL-2H-PYRAN-4-CARBOXYLATE (ESTER)
RefChem:140069
R05DB14
245-545-7
4-MORPHOLINEPROPANOL, ALPHA-METHYL-, TETRAHYDRO-4-PHENYL-2H-PYRAN-4-CARBOXYLATE (ESTER)
4-morpholin-4-ylbutan-2-yl 4-phenyloxane-4-carboxylate
Fedrilat
SCHEMBL146593
CHEMBL2104591
DTXSID70865087
CHEBI:135468
RDEOYUSTRWNWLX-UHFFFAOYSA-N
DB13825
NS00008618
D07389
Q5441137