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1-methyl-3-phenylazetidine

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Identification
Molecular formula
C10H13N
CAS number
3260-83-1
IUPAC name
1-methyl-3-phenyl-azetidine
State
State

At room temperature, 1-methyl-3-phenylazetidine is a liquid compound.

Melting point (Celsius)
-25.00
Melting point (Kelvin)
248.15
Boiling point (Celsius)
216.00
Boiling point (Kelvin)
489.15
General information
Molecular weight
147.22g/mol
Molar mass
147.2330g/mol
Density
1.0150g/cm3
Appearence

1-Methyl-3-phenylazetidine is typically a colorless to pale yellow liquid.

Comment on solubility

Solubility of 1-methyl-3-phenyl-azetidine

The solubility of 1-methyl-3-phenyl-azetidine can be understood through several important concepts. Generally, the solubility of organic compounds, particularly amines like this one, largely depends on their ability to interact with solvents.


  • Polar vs Non-polar Solvents: 1-methyl-3-phenyl-azetidine possesses both polar and non-polar characteristics due to its amine and aromatic groups, suggesting that it may be soluble in a variety of organic solvents, such as:
    • Alcohols (e.g., ethanol)
    • Aromatic hydrocarbons (e.g., toluene)
    • Chloroform
  • Hydrogen Bonding: The presence of the amine group indicates that it can participate in hydrogen bonding, which enhances its solubility in polar solvents. This interaction is crucial in solvents with the capability to donate or accept hydrogen bonds.
  • Temperature Dependency: Like many organic compounds, the solubility of 1-methyl-3-phenyl-azetidine may increase with temperature, making it easier to dissolve in higher temperatures.

In summary, while the exact solubility parameters of 1-methyl-3-phenyl-azetidine may require empirical data for precise quantification, understanding the fundamental interactions it may engage in can provide a useful framework. Remember, as a general rule of thumb, “like dissolves like,” meaning that polar and non-polar solubility characteristics will play a pivotal role in its interactions with various solvents.

Interesting facts

Exploring 1-methyl-3-phenyl-azetidine

1-methyl-3-phenyl-azetidine is a fascinating compound that belongs to the class of azetidines, which are four-membered heterocyclic rings. Here are some intriguing aspects of this compound:

  • Structural Features: The unique structure of 1-methyl-3-phenyl-azetidine includes a methyl group and a phenyl group attached to the azetidine ring, leading to interesting steric effects that influence its reactivity and properties.
  • Synthesis: This compound can be synthesized through various methods, often involving nucleophilic substitution reactions that take advantage of the ring's reactivity, providing valuable insights into synthetic organic chemistry.
  • Applications: Compounds like 1-methyl-3-phenyl-azetidine are of interest in medicinal chemistry, as they may serve as intermediates in the synthesis of pharmaceuticals or be investigated for their biological activities.
  • Importance in Chemical Research: As a building block in organic synthesis, 1-methyl-3-phenyl-azetidine is studied for its potential to create complex molecules, making it a useful compound in the design of new materials.
  • Chirality and Isomerism: The azetidine ring can exhibit chirality, leading to potential isomeric forms that may have different properties or biological activities, a topic of great interest in stereochemistry.

Overall, 1-methyl-3-phenyl-azetidine offers a rich platform for exploration in synthetic and medicinal chemistry, highlighting the intricate relationships between structure and function in chemical compounds.

Synonyms
1-Methyl-3-phenylazetidine
AZETIDINE, 1-METHYL-3-PHENYL-
3-Fenil-1-metilazetina
3-Fenil-1-metilazetina [Italian]
L 2357
BRN 1424148
DTXSID50222477
DTXCID50144968
5-20-06-00284 (beilstein handbook reference)
7215-09-0
SCHEMBL9910977