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Methyphenidate Hydrochloride

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Identification
Molecular formula
C12H13NO2
CAS number
113-45-1
IUPAC name
1-methyl-3-phenyl-pyrrolidine-2,5-dione
State
State
Solid at room temperature, it appears as crystalline powder with varying shades from pale yellow to off-white.
Melting point (Celsius)
97.00
Melting point (Kelvin)
370.15
Boiling point (Celsius)
294.00
Boiling point (Kelvin)
567.15
General information
Molecular weight
203.25g/mol
Molar mass
203.2460g/mol
Density
1.1990g/cm3
Appearence

The compound is typically found as a pale yellow to off-white crystalline powder.

Comment on solubility

Solubility Insights for 1-methyl-3-phenyl-pyrrolidine-2,5-dione

Understanding the solubility of 1-methyl-3-phenyl-pyrrolidine-2,5-dione is crucial for its potential applications in various chemical environments. Here are some key points regarding its solubility:

  • Polarity: The presence of the polar pyrrolidine ring can influence solubility in polar solvents such as water.
  • Solvent Compatibility: It is generally soluble in organic solvents, meaning it might dissolve well in:
    - Acetone
    - Ethanol
    - Methanol
  • Factors Affecting Solubility: The solubility may also be affected by factors such as temperature, concentration, and the presence of other solutes in the solution.

As a general trend, compounds with similar structures tend to display varying degrees of solubility based on their specific functional groups and overall molecular structure. In conclusion, while the solubility of 1-methyl-3-phenyl-pyrrolidine-2,5-dione can be predicted based on its chemical properties, empirical data is essential to establish precise solubility profiles in different solvents.

Interesting facts

Interesting Facts about 1-methyl-3-phenyl-pyrrolidine-2,5-dione

1-methyl-3-phenyl-pyrrolidine-2,5-dione, often referred to in scientific literature as a derivative of pyrrolidine, is a compound that has drawn interest in various fields of research due to its unique structure and potential biological activity.

Key Features:

  • Structural Versatility: This compound features a pyrrolidine ring, which is a five-membered cyclic amine, providing a flexible backbone that can participate in numerous chemical reactions.
  • Bioactive Potential: Compounds like 1-methyl-3-phenyl-pyrrolidine-2,5-dione have shown promise in medicinal chemistry. Some studies suggest that derivatives of this compound may have antioxidant and anti-inflammatory properties.
  • Synthetic Pathways: The synthesis of this compound can involve interesting organic reactions, including cyclization and substitution processes, highlighting its importance in synthetic organic chemistry.
  • Research Applications: This compound is often used as a starting material in the development of more complex molecules, making it valuable in both academic research and industrial applications.

Historical Context:

The study of pyrrolidine derivatives dates back to the early 20th century when researchers began to explore their chemical properties and potential applications. The derivatives of this compound emerged from the quest for new pharmaceuticals that could address various health issues. As organic chemistry continues to advance, the interest in compounds like 1-methyl-3-phenyl-pyrrolidine-2,5-dione reinforces the importance of pyrrolidine as a core structure in drug design.

Conclusion:

As scientists continue to investigate compounds such as 1-methyl-3-phenyl-pyrrolidine-2,5-dione, we open doors to innovative drug development and therapeutic interventions. The potential applications, combined with its intriguing chemistry, make this compound a noteworthy subject of study in the field of medicinal chemistry.

Synonyms
Phensuximide
86-34-0
Milontin
Succitimal
Lifene
Epimid
Phensuximid
1-methyl-3-phenylpyrrolidine-2,5-dione
Phenylsuximide
Milonton
phensuccimide
Fenosuccimide
Mirontin
Fensuccimide
Phensuximidum
Fensuximida
Methylphenylsuccinimide
1-Methyl-3-phenyl-2,5-pyrrolidinedione
Succinimide, N-methyl-2-phenyl-
N-Methyl-2-phenylsuccinimide
1-Methyl-3-Phenylsuccinimide
N-Methyl-alpha-phenylsuccinimide
racemic phensuximide
Fensuximida [INN-Spanish]
Phensuximidum [INN-Latin]
PM 334
1-Methyl-3-phenylpyrrolidin-2,5-dione
2,5-Pyrrolidinedione, 1-methyl-3-phenyl-
EINECS 201-664-6
UNII-6WVL9C355G
NSC-760079
BRN 0155329
6WVL9C355G
DTXSID4023460
AI3-20372
PM-334
(+/-)-N-Methyl-2-phenylsuccinimide
N-METHYL-3-PHENYLPYRROLIDINEDIONE
Phensuximide [USP:INN:BAN]
CHEBI:8079
DTXCID903460
N-Methyl-.alpha.-phenylsuccinimide
5-21-11-00188 (Beilstein Handbook Reference)
Epimid; Lifene; Milontin; Milonton
N-METHYL-3-PHENYLSUCCINIMIDE
NSC 760079
Fensuccimide [DCIT]
Fensuximida (INN-Spanish)
Phensuximidum (INN-Latin)
PHENSUXIMIDE (MART.)
PHENSUXIMIDE [MART.]
PHENSUXIMIDE (USP-RS)
PHENSUXIMIDE [USP-RS]
Phensuximide (USP:INN:BAN)
2,5-PYRROLIDINEDIONE, 1-METHYL-3-PHENYL-, (+/-)-
PHENSUXIMIDE (USP IMPURITY)
PHENSUXIMIDE [USP IMPURITY]
RS-Phensuximide
Milontin (TN)
(+-)-N-Methyl-2-phenylsuccinimide
n-methyl-2-phenyl-succinimide
CAS-86-34-0
NCGC00016339-01
MFCD00072136
Prestwick0_001061
Prestwick1_001061
Prestwick2_001061
Prestwick3_001061
Phensuximide (USP/INN)
PHENSUXIMIDE [MI]
PHENSUXIMIDE [INN]
CHEMBL797
PHENSUXIMIDE [VANDF]
SCHEMBL35333
BSPBio_001042
MLS002154134
(+/-)-PHENSUXIMIDE
PHENSUXIMIDE [WHO-DD]
2,5-Pyrrolidinedione, 1-methyl-3-phenyl-, (+-)-
SPBio_002961
BPBio1_001148
GTPL7612
N03AD02
HMS1571E04
HMS2098E04
HMS2235H10
HMS3264E08
HMS3369L21
HMS3715E04
HMS3887E05
Pharmakon1600-01505458
PHENSUXIMIDE [ORANGE BOOK]
EX-A7578
HY-B1730
Tox21_110382
AC7001
NSC760079
AKOS006230701
Tox21_110382_1
CCG-213454
DB00832
(.+/-.)-N-Methyl-2-phenylsuccinimide
NCGC00179333-01
NCGC00179333-03
AC-15962
DA-56798
MS-23022
SMR001233441
SY251116
1-Methyl-3-phenyl-2,5-pyrrolidinedione #
AB00514025
CS-0013738
NS00002015
C07437
D00508
EN300-221563
AB00514025_07
Q999805
SR-01000842158
SR-01000842158-2
BRD-A18043272-001-03-2
BRD-A18043272-001-09-9
Z360145318
201-664-6
34367-67-4