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4-(1H-indol-3-ylmethyl)-1-methylpiperidinium chloride

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Identification
Molecular formula
C15H21ClN2
CAS number
79544-08-2
IUPAC name
1-methyl-3-(piperidin-1-ium-4-ylmethyl)indole;chloride
State
State

At room temperature, 4-(1H-indol-3-ylmethyl)-1-methylpiperidinium chloride exists typically as a solid. It is not volatile and is commonly found in powder form due to its crystalline structure.

Melting point (Celsius)
193.00
Melting point (Kelvin)
466.00
Boiling point (Celsius)
270.00
Boiling point (Kelvin)
543.00
General information
Molecular weight
292.82g/mol
Molar mass
292.8240g/mol
Density
1.2500g/cm3
Appearence

4-(1H-indol-3-ylmethyl)-1-methylpiperidinium chloride typically appears as a crystalline solid. The crystals are colorless to pale yellow, although occasionally, they can appear off-white. This compound may absorb moisture from the air due to its hygroscopic nature.

Comment on solubility

Solubility of 1-methyl-3-(piperidin-1-ium-4-ylmethyl)indole;chloride

The solubility of 1-methyl-3-(piperidin-1-ium-4-ylmethyl)indole;chloride can be influenced by various factors, notably its ionic nature and molecular structure. Typically, compounds containing quaternary ammonium structures like this one tend to exhibit considerable solubility in polar solvents. Here are a few key points regarding its solubility:

  • Water Solubility: The chloride component may enhance the compound's ability to dissolve in water, making it potentially soluble or even very soluble depending on concentration.
  • Solvent Effects: Solubility can be higher in organic solvents compared to water, especially in polar organic solvents like acetone or ethanol.
  • Ionization: The presence of the piperidinium group suggests the compound might exist in an ionized form in the presence of moisture, which often increases solubility.

In conclusion, while the solubility of 1-methyl-3-(piperidin-1-ium-4-ylmethyl)indole;chloride is largely dictated by its ionic nature and interactions with solvents, conducting empirical solubility tests across different solvents would provide the most accurate and conclusive data.

Interesting facts

Interesting Facts about 1-methyl-3-(piperidin-1-ium-4-ylmethyl)indole;chloride

1-methyl-3-(piperidin-1-ium-4-ylmethyl)indole;chloride is a fascinating compound largely studied for its potential applications in various fields, particularly in medicinal chemistry. Here are some intriguing aspects to consider:

  • Complex Structure: The compound features a unique structure that incorporates both an indole and a piperidine moiety, showcasing the versatility of organic syntheses.
  • Biological Relevance: Compounds related to indoles have been implicated in various biological activities. Indoles can act as neurotransmitter precursors, which means they may influence mood and cognitive function.
  • Learning Opportunities: For chemistry students, synthesizing or studying this compound can be a great way to learn about reaction mechanisms involving nitrogen-containing heterocycles, as well as techniques such as chromatography for purification.
  • Research Insight: Researchers are keenly interested in its potential as a therapeutic agent. Some studies suggest compounds with similar structures may exhibit activity against various diseases, including cancer.
  • Customizability: The presence of various functional groups in its structure allows chemists to modify the compound, potentially leading to the development of new derivatives with enhanced properties.

As emphasized by many in the field, "the complexity of organic compounds often leads to unexpected therapeutic discoveries." Continuing to explore compounds like 1-methyl-3-(piperidin-1-ium-4-ylmethyl)indole;chloride may unravel new insights into how small changes in structure can significantly influence biological activity.

This compound is a prime example of the intricate relationships between chemistry and biology, demonstrating how understanding molecular structure can lead to innovative solutions in drug development.

Synonyms
3558-36-9
1-Methyl-3-(4-piperidinomethyl)indole hydrochloride
INDOLE, 1-METHYL-3-(4-PIPERIDYLMETHYL)-, HYDROCHLORIDE
4-[(1-methyl-1H-indol-3-yl)methyl]piperidinium chloride