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Tropacocaine hydrochloride

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Identification
Molecular formula
C21H30ClNO2
CAS number
2058-03-1
IUPAC name
(1-methyl-3-piperidyl) 2-cyclohexyl-2-hydroxy-2-phenyl-acetate;hydrochloride
State
State

At room temperature, the compound is in a solid state.

Melting point (Celsius)
230.00
Melting point (Kelvin)
503.15
Boiling point (Celsius)
245.00
Boiling point (Kelvin)
518.15
General information
Molecular weight
357.93g/mol
Molar mass
357.9250g/mol
Density
1.0812g/cm3
Appearence

The compound typically appears as a crystalline powder, which is often colorless or may have a slightly yellowish hue.

Comment on solubility

Solubility of (1-methyl-3-piperidyl) 2-cyclohexyl-2-hydroxy-2-phenyl-acetate; hydrochloride

The solubility of the compound (1-methyl-3-piperidyl) 2-cyclohexyl-2-hydroxy-2-phenyl-acetate; hydrochloride can be influenced by a variety of factors such as its molecular structure, the presence of functional groups, and the solvent used. Understanding its solubility is essential for applications in pharmaceuticals, where solubility plays a critical role in bioavailability.

Key points to consider regarding solubility:

  • Hydrochloride salt formation: The hydrochloride form of this compound often indicates higher solubility in water compared to its free base counterpart, due to greater ionic interactions.
  • Polarity: The presence of polar functional groups, such as hydroxyl (-OH), can enhance solubility in polar solvents like water but may limit solubility in non-polar solvents.
  • Hydrogen bonding: Functional groups capable of forming hydrogen bonds will typically have increased solubility in polar solvents.
  • Temperature effects: Solubility can also vary with temperature; generally, solubility increases with temperature for most solids.

In conclusion, the solubility of (1-methyl-3-piperidyl) 2-cyclohexyl-2-hydroxy-2-phenyl-acetate; hydrochloride is expected to be moderate to high in water and may require further experimental analysis to ascertain its solubility in organic solvents. Understanding the solubility characteristics can lead to better formulation strategies in drug development.

Interesting facts

Interesting Facts About (1-Methyl-3-piperidyl) 2-Cyclohexyl-2-Hydroxy-2-Phenyl-Acetate Hydrochloride

(1-Methyl-3-piperidyl) 2-cyclohexyl-2-hydroxy-2-phenyl-acetate hydrochloride is an intriguing compound, particularly known for its applications in medicinal chemistry. This compound belongs to a class of molecules that often exhibit distinctive biological activities, making them valuable in pharmaceutical development.

Key Highlights:

  • Pharmaceutical Role: This compound is often explored for its potential therapeutic effects, especially in the treatment of various neurological disorders.
  • Structural Complexity: The presence of a piperidine ring combined with a cyclohexyl and phenyl groups contributes to its unique properties, affecting its interaction with biological targets.
  • Chirality and Isomerism: The stereochemistry of the compound can significantly influence its biological activity, making the study of its isomers an important area of research.
  • Research Potential: Ongoing studies investigate the compound’s mechanism of action, looking for new insights that may lead to improved therapeutic outcomes.
  • Anticholinergic Activity: Some derivatives of this structure might exhibit anticholinergic effects, indicating potential uses in treating certain conditions by modulating neurotransmitter systems.

In summary, the chemical landscape of (1-Methyl-3-piperidyl) 2-cyclohexyl-2-hydroxy-2-phenyl-acetate hydrochloride is rich and complex, filled with possibilities for further exploration in medicinal chemistry. As scientists continue to unravel the mechanisms behind its effects, this compound stands as a testament to the intricate relationships between structure and function in drug design.

In the words of chemists, "Every compound tells a story; it is our job to read it and understand its potential." This sentiment drives the ongoing research into compounds like this one, encouraging a deeper investigation into their capabilities and effects.

Synonyms
36616-48-5
(1-methylpiperidin-3-yl) 2-cyclohexyl-2-hydroxy-2-phenylacetate;hydrochloride
SCHEMBL563864
CHEMBL2107115
DTXSID70931291
NSC172243
NSC-172243
WLN: T6NTJ A1 COVXQR&- AL6TJ &GH
D05628
Benzeneacetic acid, 1-methyl-3-piperidinyl ester, hydrochloride (VA
1-Methylpiperidin-3-yl cyclohexyl(hydroxy)phenylacetate--hydrogen chloride (1/1)