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1-Methyl-3,4-dihydroisoquinoline-6,7-diol

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Identification
Molecular formula
C10H11NO2
CAS number
/
IUPAC name
1-methyl-3,4-dihydroisoquinoline-6,7-diol
State
State

At room temperature, 1-Methyl-3,4-dihydroisoquinoline-6,7-diol is typically in a solid state.

Melting point (Celsius)
192.00
Melting point (Kelvin)
465.15
Boiling point (Celsius)
325.00
Boiling point (Kelvin)
598.15
General information
Molecular weight
177.20g/mol
Molar mass
177.1960g/mol
Density
1.2400g/cm3
Appearence

1-Methyl-3,4-dihydroisoquinoline-6,7-diol appears as a solid at room temperature. It typically has a light color, ranging from white to off-white or pale yellow. The appearance may vary slightly depending on purity and specific crystal form.

Comment on solubility

Solubility of 1-methyl-3,4-dihydroisoquinoline-6,7-diol

1-methyl-3,4-dihydroisoquinoline-6,7-diol, with its complex chemical structure, exhibits interesting solubility characteristics that can influence its applications in various fields. The solubility of this compound is primarily affected by the following factors:

  • Polarity: The presence of hydroxyl (-OH) groups in the chemical structure enhances its polarity, which may promote solubility in polar solvents such as water.
  • Hydrogen Bonding: The ability to form hydrogen bonds allows 1-methyl-3,4-dihydroisoquinoline-6,7-diol to dissolve more readily in aqueous solutions, contributing to its stability in biological systems.
  • Steric Hindrance: The methyl group can introduce some steric hindrance, which might affect the degree to which this compound can solvate with solvents, thus impacting solubility.

As a general rule, compounds that contain multiple -OH groups tend to have increased solubility in polar solvents due to their capability to interact favorably with solvent molecules. Despite this, the exact solubility can vary significantly based on the specific conditions of the solvent, such as:

  • Temperature: Solubility typically increases with higher temperatures.
  • pH Levels: The compound's ionization under different pH conditions can alter its solubility.

In summary, the solubility of 1-methyl-3,4-dihydroisoquinoline-6,7-diol is a complex interplay of molecular interactions and environmental factors, making it a compound of interest for research and applications in pharmaceuticals and material sciences.

Interesting facts

Interesting Facts about 1-methyl-3,4-dihydroisoquinoline-6,7-diol

1-methyl-3,4-dihydroisoquinoline-6,7-diol is a fascinating compound that is of particular interest in the fields of medicinal chemistry and pharmacology. Its unique structure allows for various biological activities and potential applications in the development of therapeutic agents.

Biological Significance

  • Neuroprotective Properties: Some studies suggest that this compound possesses neuroprotective properties, making it a candidate for the treatment of neurodegenerative diseases.
  • Antioxidant Activity: With its ability to scavenge free radicals, it is considered a promising agent in combating oxidative stress.
  • Potential in Pain Management: Research has indicated that it may have analgesic effects, presenting an avenue for developing new pain management therapies.

Chemical Characteristics

The presence of the isoquinoline ring in its structure lends to a rich tapestry of chemical reactivity. This enables scientists to:

  • Modify the compound and create derivatives with enhanced efficacy.
  • Explore various synthetic pathways to optimize yield and purity.
  • Investigate interactions with biological targets to better understand its mechanism of action.

Quote

As one researcher aptly stated, "Exploring the chemistry of 1-methyl-3,4-dihydroisoquinoline-6,7-diol is not just an academic exercise; it opens doors to potential breakthroughs in medicine."

In summary, the study of 1-methyl-3,4-dihydroisoquinoline-6,7-diol not only adds to our understanding of isoquinoline derivatives but also fuels our hopes for future therapeutic developments. Its unique properties make it a prime candidate for further investigation, suggesting that the journey into its chemical wonders is far from over.

Synonyms
1,2-Dehydrosalsolinol
DSAL
4602-81-7
1-methyl-3,4-dihydroisoquinoline-6,7-diol
139080-83-4
7-Hydroxy-1-methyl-3,4-dihydroisoquinolin-6(2H)-one
6,7-Isoquinolinediol, 3,4-dihydro-1-methyl-
3,4-dihydro-1-methyl-6,7-Isoquinolinediol
CHEMBL60503
SCHEMBL18932930
DTXSID20963486
CHEBI:178978
AKOS024370379
1-methyl-3,4-di-hydro-6,7-isoquinolinediol
1-Methyl-6,7-dihydroxy-3,4-dihydroisoquinolines