Mirtazapine | Solubility of Things

Identification

Molecular formula

C₁₇H₁₉N₃O

CAS number

61337-67-5

IUPAC name

1-methyl-4-(3-nitro-5,6-dihydrobenzo[b][1]benzothiepin-5-yl)piperazine

State

Mirtazapine is typically in a solid state at room temperature.

Melting point (Celsius)

114.00

Melting point (Kelvin)

387.20

Boiling point (Celsius)

492.40

Boiling point (Kelvin)

765.60

General information

Molecular weight

264.36g/mol

Molar mass

264.3580g/mol

Density

1.3020g/cm³

Appearence

Mirtazapine appears as a white to cream-colored crystalline powder.

Comment on solubility

Solubility of 1-methyl-4-(3-nitro-5,6-dihydrobenzo[b][1]benzothiepin-5-yl)piperazine

The solubility of 1-methyl-4-(3-nitro-5,6-dihydrobenzo[b][1]benzothiepin-5-yl)piperazine is influenced by several factors, largely related to its complex structure. Here's a breakdown to consider:

Polarity: The presence of several functional groups, including the nitro group and the piperazine ring, suggests that the compound could exhibit varying degrees of polarity, affecting its solubility in different solvents.
Solvent Compatibility: Typically, compounds like this may show increased solubility in polar organic solvents such as dimethyl sulfoxide (DMSO) or methanol, while having limited solubility in non-polar solvents.
pH Sensitivity: The presence of nitrogen atoms may allow the compound to ionize under certain pH conditions, which can enhance its solubility in aqueous solutions if the pH is appropriately adjusted.
Thermodynamic Factors: The temperature may also play a crucial role, as increasing temperature often enhances solubility for many organic compounds.

In summary, while the specific solubility data for this compound might be scarce, one can infer that factors such as polarity, solvent type, pH level, and temperature will significantly dictate its solubility behavior. Further experimental studies would be vital to characterize its solubility profile more explicitly.

Interesting facts

Exploring 1-Methyl-4-(3-nitro-5,6-dihydrobenzo[b][1]benzothiepin-5-yl)piperazine

1-Methyl-4-(3-nitro-5,6-dihydrobenzo[b][1]benzothiepin-5-yl)piperazine is a fascinating compound in the realm of medicinal chemistry, particularly due to its complex structure and potential biological activity. Here are some intriguing aspects of this compound:

Unique Structural Features: This compound incorporates a piperazine ring—a common motif in many pharmaceuticals—alongside a nitro-substituted benzothiepin structure. This combination may contribute to its potential pharmacological properties.
Biological Activity: Compounds that exhibit such structural diversity often have interesting biological activities. Researchers speculate that similar compounds may act on various neurotransmitter systems, making them subjects of interest for the development of treatments for neuropsychiatric disorders.
Impact of Substituents: The presence of the nitro group is noteworthy as it can significantly influence the electronic properties of the molecule, possibly enhancing its interaction with biological targets. The overall reactivity and stability of the compound are also impacted by this substitution.
Synthetic Pathways: The synthesis of such complex organic molecules poses interesting challenges for synthetic chemists. Understanding the different methods available for constructing these compounds can lead to innovations in synthetic methodology.
Potential Applications: Given its structural elements, there is a potential for developing this compound or derivatives thereof as therapeutics in treating conditions such as depression or anxiety, making it a promising candidate for further investigation.

In summary, 1-methyl-4-(3-nitro-5,6-dihydrobenzo[b][1]benzothiepin-5-yl)piperazine embodies the intricate relationship between structure and function in chemical compounds, highlighting the ongoing need for research in this area. As with many complex organic compounds, the journey of discovery may lead to significant advancements in medicinal chemistry.

Synonyms

AKOS005065459