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Toluene-4-sulfonyl methyl

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Identification
Molecular formula
C8H10O2S
CAS number
104-15-4
IUPAC name
1-methyl-4-methylsulfonyl-benzene
State
State
At room temperature, 1-methyl-4-methylsulfonyl-benzene exists as a solid. It is typically crystalline in form.
Melting point (Celsius)
83.00
Melting point (Kelvin)
356.15
Boiling point (Celsius)
292.00
Boiling point (Kelvin)
565.15
General information
Molecular weight
170.23g/mol
Molar mass
170.2200g/mol
Density
1.2298g/cm3
Appearence

1-Methyl-4-methylsulfonyl-benzene, also known as toluene-4-sulfonyl methyl, is a white crystalline solid. Its appearance is consistent with many sulfonyl compounds, displaying a fine powder or granular form.

Comment on solubility

Solubility of 1-methyl-4-methylsulfonyl-benzene

The solubility of 1-methyl-4-methylsulfonyl-benzene, also known by its IUPAC name, plays a crucial role in its application across various fields, particularly in organic synthesis and pharmaceuticals. This compound exhibits specific solubility characteristics due to several factors:

  • Polarity: The presence of the methylsulfonyl group enhances the overall polarity of the molecule, allowing it to interact more favorably with polar solvents.
  • Solvent Interaction: 1-methyl-4-methylsulfonyl-benzene tends to be more soluble in polar organic solvents such as ethanol and acetone, whereas it exhibits lower solubility in non-polar solvents like hexane.
  • Temperature Dependency: Like many compounds, its solubility may increase with temperature due to enhanced molecular movement, facilitating the dissolution process.

In summary, 1-methyl-4-methylsulfonyl-benzene is primarily soluble in polar solvents, demonstrating a clear relationship between its chemical structure and solubility behavior. Understanding these solubility dynamics can aid in optimizing its use in various chemical processes.

Interesting facts

Interesting Facts about 1-Methyl-4-methylsulfonyl-benzene

1-Methyl-4-methylsulfonyl-benzene, also known as p-Toluenesulfonamide, is a fascinating compound with various applications in both industrial and research settings. This compound is a derivative of toluene, where a methylsulfonyl group replaces one of the hydrogen atoms on the aromatic ring.

Key Features:

  • Versatile Building Block: It is often used as an important building block in organic synthesis, paving the way for more complex molecules.
  • Pharmaceutical Applications: The compound is utilized in the pharmaceutical industry, particularly in the synthesis of drugs and agrochemicals.
  • Functional Group Highlights: The presence of the methylsulfonyl group enhances the solubility of the compound, leading to better interaction with biological systems.

One interesting aspect of 1-methyl-4-methylsulfonyl-benzene is its role in the derivatization of amino acids and peptides. Scientists often employ this compound to enhance the properties and reactivity of such biomolecules, thereby facilitating research in biochemistry and medicinal chemistry.

Quote:

As stated by renowned chemist Charles P. Snyder, "The incorporation of sulfonyl groups into organic compounds opens new avenues for functionalization and reactivity."

Furthermore, the compound's structural integrity and reactivity profile make it an exemplary subject for studies in the field of synthetic chemistry. With ongoing research, 1-methyl-4-methylsulfonyl-benzene continues to showcase its significance in advancing chemical knowledge and applications.

Synonyms
3185-99-7
Methyl p-tolyl sulfone
1-Methyl-4-(methylsulfonyl)benzene
p-Tolyl methyl sulfone
Benzene, 1-methyl-4-(methylsulfonyl)-
Sulfone, methyl p-tolyl
p-(Methylsulphonyl)toluene
p-(methylsulfonyl)toluene
NSC 2722
NSC 29038
TG77SM513A
NSC-2722
EINECS 221-682-8
NSC-29038
DTXSID6075229
4-METHYLPHENYL METHYL SULFONE
pTolyl methyl sulfone
Sulfone, methyl ptolyl
4(Methylsulfonyl)toluene
p(Methylsulphonyl)toluene
Sulfone, methyl ptolyl (8CI)
DTXCID3038434
Sulfone, methyl p-tolyl (8CI)
Benzene, 1methyl4(methylsulfonyl)
Benzene, 1methyl4(methylsulfonyl) (9CI)
Benzene, 1-methyl-4-(methylsulfonyl)-(9CI)
221-682-8
inchi=1/c8h10o2s/c1-7-3-5-8(6-4-7)11(2,9)10/h3-6h,1-2h
4-(Methylsulfonyl)toluene
1-methyl-4-methylsulfonylbenzene
Methylp-TolylSulfone
59203-01-9
1-methanesulfonyl-4-methylbenzene
Methyl 4-tolyl sulfone
MFCD00014742
1-Methanesulfonyl-4-methyl-benzene
UNII-TG77SM513A
p-tolylmethylsulphone
Ts-Me
Methyl p-tolylsulfone
4-methylsulfonyltoluene
Methyl p-tolyl sulphone
(p-Tolylsulfonyl)methane
Maybridge4_002299
methyl-p-toluene sulfonate
SCHEMBL12807
METHYL 4-TOLYLSULFONE
SCHEMBL9541106
methyl-(4-methylphenyl)sulphone
CHEMBL1088935
1-Methansulfonyl-4-methylbenzene
NSC2722
4-(Methylsulfonyl)toluene, 97%
HMS1527I11
4-methanesulfonyl-1-methyl-benzene
NSC29038
CCG-49782
1-Methyl-4-(methyl-sulphonyl)benzene
1-Methyl-4-(methylsulfonyl)benzene #
AKOS000352549
FS-1023
NCGC00176705-01
AC-18789
SY002922
CS-0117038
M0842
NS00029185
D70958
EN300-295475
AE-095/31500059
SR-01000639213-1
BRD-K92730216-001-01-4
Q27289950