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1-Methyl-4-nitroimidazole

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Identification
Molecular formula
C4H5N3O2
CAS number
3034-38-6
IUPAC name
1-methyl-4-nitro-imidazole
State
State

At room temperature, 1-Methyl-4-nitroimidazole is a solid. It is often described as a stable compound when kept in well-sealed containers and away from light and moisture.

Melting point (Celsius)
56.00
Melting point (Kelvin)
329.15
Boiling point (Celsius)
287.00
Boiling point (Kelvin)
560.15
General information
Molecular weight
127.11g/mol
Molar mass
127.1080g/mol
Density
1.3500g/cm3
Appearence

1-Methyl-4-nitroimidazole typically appears as a yellow crystalline solid. It often takes the form of elongated prismatic crystals that may exhibit slight hygroscopic characteristics, absorbing moisture from the air.

Comment on solubility

Solubility of 1-Methyl-4-nitro-imidazole

1-Methyl-4-nitro-imidazole is a compound whose solubility can significantly influence its applications and behavior in various environments. Here are some key points regarding its solubility:

  • Solvent Compatibility: This compound tends to be soluble in organic solvents such as ethanol and acetone, which indicates a preference for non-polar to moderately polar environments.
  • Water Solubility: It is generally considered to have low solubility in water. This low water solubility can impact its usability in biological systems and applications that require aqueous environments.
  • Influencing Factors: The solubility can be affected by factors such as temperature and the presence of other solutes. Higher temperatures often increase solubility, while the presence of salts may decrease it by introducing competition for solvation.
  • pH Influence: The solubility may also be affected by the pH of the solution, as protonation states can alter the compound's interaction with solvent molecules.

In summary, while 1-methyl-4-nitro-imidazole exhibits solubility in specific organic solvents, its limited solubility in water makes understanding its behavior essential for effective application in various fields.

Interesting facts

Interesting Facts About 1-Methyl-4-nitro-imidazole

1-Methyl-4-nitro-imidazole is a fascinating compound that holds significance in various fields of chemistry and medicinal research. Here are some compelling points about this compound:

  • Structure & Chemistry: The imidazole ring in this compound is a 5-membered aromatic heterocycle containing two nitrogen atoms, which contributes to its reactivity and interaction with various biological systems.
  • Pharmaceutical Relevance: Compounds similar to 1-methyl-4-nitro-imidazole are often explored for their potential antimicrobial and anti-parasitic properties. The presence of nitro groups is crucial due to their role in bioactivity.
  • Research Applications: This compound has been utilized as a building block in synthesizing more complex molecules in drug discovery, particularly in the development of antifungal agents and other therapeutic drugs.
  • Reaction with Biological Systems: The unique nitrogen atoms allow it to engage in hydrogen bonding, modifying the physical and biological interactions with other molecules. This property can potentially enhance targeted drug profiles.
  • Environmental Impact: Understanding the degradation pathways of nitro compounds like 1-methyl-4-nitro-imidazole can contribute to environmental chemistry, particularly in assessing the biocompatibility and toxicity of chemical substances.

In summary, while 1-methyl-4-nitro-imidazole may seem like a simple compound, its implications in pharmaceuticals and environmental chemistry denote its importance. As we continue to explore the realm of chemical compounds, we discover that even the smallest structures can pose significant influence in biological and ecological systems.

Synonyms
1-Methyl-4-nitroimidazole
1-Methyl-4-nitro-1H-imidazole
Imidazole, 1-methyl-4-nitro-
BRN 0123533
UNII-Z31100A55O
AI3-51824
Z31100A55O
METRONIDAZOLE IMPURITY I
DTXSID50184425
5-23-04-00486 (Beilstein Handbook Reference)
DTXCID60106916
1-Methyl-4-nitro-1H-imidazole (9CI)
802-213-1
hscoldqjzrzqmv-uhfffaoysa-n
3034-41-1
1H-Imidazole, 1-methyl-4-nitro-
CHEBI:80615
MFCD00159683
3-methyl-5-nitroimidazole
SCHEMBL174098
CHEMBL3544543
CL2229
STK760074
AKOS000601578
CS-W018929
NCGC00340396-01
AC-23143
DS-17161
SY041755
DB-068272
EU-0052121
M3171
AB01332166-02
Q27149662
1-Methyl-4-nitro-1H-imidazole; 1-Methyl-4-nitro-imidazole