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N-Nitroso-N-methylpiperazine

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Identification
Molecular formula
C5H11N3O
CAS number
16339-04-1
IUPAC name
1-methyl-4-nitroso-piperazine
State
State

At room temperature, N-Nitroso-N-methylpiperazine is generally found as a liquid due to its low melting point of -45°C. Given its melting and boiling points, it tends to exist in a liquid state at room temperature.

Melting point (Celsius)
-45.00
Melting point (Kelvin)
228.15
Boiling point (Celsius)
154.00
Boiling point (Kelvin)
427.15
General information
Molecular weight
129.16g/mol
Molar mass
129.1550g/mol
Density
1.0900g/cm3
Appearence

N-Nitroso-N-methylpiperazine is typically a yellow oily or waxy solid. Its appearance can vary slightly based on purity and ambient temperature.

Comment on solubility

Solubility of 1-methyl-4-nitroso-piperazine

1-methyl-4-nitroso-piperazine, a nitrogen-containing organic compound, demonstrates varying solubility characteristics that can be intriguing. When assessing the solubility of this compound, consider the following key points:

  • Solvent compatibility: 1-methyl-4-nitroso-piperazine is primarily soluble in polar solvents, particularly in water and alcohols. This is due to its functional groups, which can interact favorably with similar types of solvent molecules.
  • Temperature influence: Generally, the solubility of organic compounds can increase with temperature. However, it's essential to conduct experiments at different temperatures to determine the precise solubility limits for this compound.
  • pH effects: The solubility may be affected by the pH of the solution, as acidic or basic environments can alter the ionization state of the compound, which in turn impacts its overall solubility.
  • Potential formation of complexes: In some cases, 1-methyl-4-nitroso-piperazine may form complexes with other molecules in solution, which can either increase or decrease its solubility depending on the nature of those interactions.

In summary, the solubility of 1-methyl-4-nitroso-piperazine is influenced by several factors, making it essential to evaluate experimental conditions closely. Understanding these variables can significantly aid in the effective application and utilization of this compound in various chemical processes.

Interesting facts

Interesting Facts about 1-Methyl-4-Nitroso-Piperazine

1-Methyl-4-nitroso-piperazine is a fascinating compound that has garnered interest in various fields of chemistry and pharmacology. Here are some informative points about this compound:

  • Synthesis and Structure: 1-Methyl-4-nitroso-piperazine belongs to a class of compounds known as piperazines, which features a six-membered ring containing nitrogen atoms. The presence of the nitroso group (-NO) enhances its reactivity and potential applications.
  • Pharmaceutical Relevance: Compounds similar to 1-methyl-4-nitroso-piperazine are often investigated for their biological activities. This compound may serve as a precursor for synthesizing more complex pharmaceutical agents or could lead to novel therapeutic avenues.
  • Chemical Reactivity: The nitroso group is known for its ability to participate in various chemical reactions. It can act as a nitrosating agent, which can introduce the nitroso moiety into other organic molecules, making it a valuable intermediate in organic synthesis.
  • Implications in Research: Ongoing research aims to understand the interactions of nitroso compounds with biological systems. Such studies may unveil new insights into mechanisms of toxicity, as well as opportunities for drug development.
  • Safety Considerations: As with many nitroso compounds, handling 1-methyl-4-nitroso-piperazine may require safety precautions due to potential health risks associated with nitroso group exposure, which can include carcinogenic properties in some contexts.

In summary, 1-methyl-4-nitroso-piperazine is more than just a chemical compound; it is a valuable entity in the world of chemistry that can pave the way for advancements in medicinal chemistry and organic synthesis.

Synonyms
1-Methyl-4-nitrosopiperazine
16339-07-4
PIPERAZINE, 1-METHYL-4-NITROSO-
1-Nitroso-4-methylpiperazine
N-Nitroso-N'-methylpiperazine
5584MPJ7F2
NSC-523886
DTXSID30167574
DTXCID8090065
240-409-3
N-Methyl-N'-nitrosopiperazine
Methylnitrosopiperidine
N-Methyl-npz
N-Methylnitrosopiperazine
Methylpiperazinenitrosamine
N-Nitroso-N'-methylpiperazin
N'-Methyl-N-nitrosopiperazine
1-Methyl-4-nitroso-piperazine
MFCD01702457
NSC 523886
CCRIS 1151
EINECS 240-409-3
N-Nitroso-N'-methylpiperazin [German]
BRN 0117135
UNII-5584MPJ7F2
1-Methyl-4-nitrosopiperazine; 1-Nitroso-4-methylpiperazine; N-Nitroso-N'-methylpiperazine; NSC 523886;
5-23-03-00220 (Beilstein Handbook Reference)
N-Methyl-N?-nitrosopiperazine
CHEMBL164193
SCHEMBL11623926
WLN: T6N DNTJ ANO D1
NSC523886
AKOS006276505
HY-W663740
METHYL-4-NITROSOPIPERAZINE, 1-
AS-60418
FM171623
SY270779
NS00025333
D92907
EN300-25386041
A1-88864
N-Methyl-N'-nitrosopiperazine (100mg/L in Methanol)
Q27261293
Z1198157883