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Meperidine

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Identification
Molecular formula
C17H23NO2
CAS number
60-29-7
IUPAC name
(1-methyl-4-piperidyl) 2-methoxy-2,2-diphenyl-acetate
State
State

At room temperature, Meperidine is typically encountered as a solid, which can be processed into a liquid form if prepared as a hydrochloride salt for clinical or pharmaceutical use.

Melting point (Celsius)
33.00
Melting point (Kelvin)
306.15
Boiling point (Celsius)
318.00
Boiling point (Kelvin)
591.15
General information
Molecular weight
267.36g/mol
Molar mass
267.3600g/mol
Density
1.1865g/cm3
Appearence

The appearance of this compound is typically a white crystalline powder. It is often supplied in a hydrochloride salt form for enhanced solubility in aqueous solutions, particularly for pharmaceutical applications.

Comment on solubility

Solubility of (1-methyl-4-piperidyl) 2-methoxy-2,2-diphenyl-acetate

The solubility characteristics of the compound (1-methyl-4-piperidyl) 2-methoxy-2,2-diphenyl-acetate are influenced by its unique molecular structure. Several factors contribute to its solubility profile:

  • Polarity: The presence of both hydrophobic (diphenyl groups) and hydrophilic (methoxy group) functional groups affects solubility in different solvents.
  • Solvent Types: Generally, this compound shows better solubility in organic solvents such as:
    • Ethyl acetate
    • Chloroform
    • Dichloromethane
  • Water Solubility: This compound is expected to have low solubility in water due to its predominantly non-polar character.
  • Temperature Influence: As with many organic compounds, increasing temperature may enhance solubility, allowing for *greater molecular interaction* in the solvent.

In summary, (1-methyl-4-piperidyl) 2-methoxy-2,2-diphenyl-acetate exhibits selective solubility properties, favoring organic solvents over polar systems like water. This characteristic is crucial for its applications in various fields, including pharmaceuticals and organic synthesis.

Interesting facts

Interesting Facts about (1-methyl-4-piperidyl) 2-methoxy-2,2-diphenyl-acetate

(1-methyl-4-piperidyl) 2-methoxy-2,2-diphenyl-acetate is a fascinating compound that showcases a blend of organic chemistry and pharmacology. It can be classified as a piperidine derivative, which has significant implications in medicinal chemistry. Here are some interesting aspects of this compound:

  • Structural Diversity: This compound is characterized by a piperidine ring, combined with a methoxy group and a diphenyl-acetate moiety, making it structurally unique. The inclusion of these functional groups contributes to its diverse activity.
  • Potential Therapeutic Applications: Due to its structure, compounds of a similar nature are often investigated for their pharmacological properties. They may have potential uses in the treatment of neurological disorders or as analgesic agents.
  • Importance in Drug Design: The presence of a piperidine ring makes this compound relevant in the development of new pharmaceuticals. The ability to modify the piperidine scaffold can lead to various derivatives with enhanced efficacy and selectivity.
  • Chirality Considerations: With the presence of multiple stereocenters, this compound opens discussions on chirality in medicinal chemistry, where the arrangement of molecules can significantly affect their biological activity.
  • Research Opportunities: The synthesis and characterization of (1-methyl-4-piperidyl) 2-methoxy-2,2-diphenyl-acetate provide ample opportunities for research, particularly in exploring its potential reactions and interactions with biological systems.

As noted by researchers, "The intricate balance of structure and function in organic compounds often leads to surprises in their therapeutic potential." This sentiment rings true for compounds like (1-methyl-4-piperidyl) 2-methoxy-2,2-diphenyl-acetate, where careful exploration could yield exciting new discoveries in the realm of chemistry and medicine.

Synonyms
60569-20-2
DTXSID801203653
1-Methyl-4-piperidinyl alpha-methoxy-alpha-phenylbenzeneacetate
1-Methyl-4-piperidinyl I+/--methoxy-I+/--phenylbenzeneacetate