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Nicotyrine

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Identification
Molecular formula
C10H12N2O
CAS number
487-19-4
IUPAC name
1-methyl-5-(3-pyridyl)pyrrolidin-2-one
State
State

The compound is typically found as a solid at room temperature and can exist in a crystalline form due to its molecular structure.

Melting point (Celsius)
61.00
Melting point (Kelvin)
334.15
Boiling point (Celsius)
335.00
Boiling point (Kelvin)
608.15
General information
Molecular weight
160.21g/mol
Molar mass
160.2070g/mol
Density
1.1500g/cm3
Appearence

Nicotyrine is a white to off-white solid that may also appear in crystalline form. It has the structural complexity associated with pyrrolidinone and pyridine moieties, giving it a distinct chemical appearance.

Comment on solubility

Solubility of 1-methyl-5-(3-pyridyl)pyrrolidin-2-one

1-methyl-5-(3-pyridyl)pyrrolidin-2-one (C10H12N2O) demonstrates intriguing solubility characteristics that are important to consider in various applications. This compound is known to be:

  • Moderately soluble in water: 1-methyl-5-(3-pyridyl)pyrrolidin-2-one's structure allows for some degree of interaction with water molecules due to its polar functional groups.
  • Soluble in organic solvents: Its lipophilic properties enable it to dissolve readily in organic solvents such as ethanol, methanol, and DMSO, making it suitable for various chemical processes.

When examining solubility, it is crucial to consider factors such as:

  1. Temperature: Increased temperature generally enhances solubility for many organic compounds.
  2. pH Level: The solubility of this compound can be affected by the pH of the solution, potentially leading to ionization or protonation changes.

Overall, the solubility profile of 1-methyl-5-(3-pyridyl)pyrrolidin-2-one is influenced by both its molecular structure and surrounding environmental conditions, which could provide insightful implications for its practical uses in pharmaceutical formulations and chemical syntheses.

Interesting facts

Interesting Facts about 1-methyl-5-(3-pyridyl)pyrrolidin-2-one

1-methyl-5-(3-pyridyl)pyrrolidin-2-one is a fascinating compound that belongs to the class of pyrrolidine derivatives. As a scientist, I find its unique structure and functional properties incredibly intriguing. Here are some interesting points:

  • Structural Importance: The compound features a pyrrolidine ring, which is a five-membered nitrogen-containing heterocycle. This structural motif is notable for its presence in various natural products and bioactive molecules.
  • Biological Activity: Several studies suggest that compounds similar to 1-methyl-5-(3-pyridyl)pyrrolidin-2-one exhibit potential therapeutic effects, including neuroprotective and cognitive-enhancing properties. This makes them candidates for research in drug development.
  • Pharmacological Potential: The presence of the pyridine group in the molecule indicates the potential for interactions with biological systems, such as targeting receptors or enzymes, which could lead to novel pharmacological applications.
  • Synthetic Versatility: One of the remarkable aspects of this compound is its synthetic accessibility. Chemists can prepare it through various methods, allowing for modifications to the structure that can lead to analogs with enhanced properties.

As quoted, "The beauty of chemistry lies in its ability to connect seemingly unrelated disciplines." In the case of 1-methyl-5-(3-pyridyl)pyrrolidin-2-one, it connects organic synthesis, pharmacology, and medicinal chemistry, showcasing the interdisciplinary nature of chemical research.

Overall, the study of 1-methyl-5-(3-pyridyl)pyrrolidin-2-one not only contributes to our understanding of chemical compounds but also highlights the potential for innovative solutions in medicinal chemistry.

Synonyms
15569-85-4
rac Cotinine
1-Methyl-5-(3-pyridinyl)-2-pyrrolidinone
rac-Cotinine
1-methyl-5-(pyridin-3-yl)pyrrolidin-2-one
2-Pyrrolidinone, 1-methyl-5-(3-pyridinyl)-
1-methyl-5-pyridin-3-ylpyrrolidin-2-one
CHEMBL664
66269-66-7
(+/-)-Cotinine
COTININE(15% OF THE DOSE)
NCGC00093739-04
(-)-Cotinine;(S)-Cotinine;NIH-10498
SCHEMBL49061
DTXSID6047577
BDBM82069
CHEBI:182609
HMS3370B20
HMS3393A15
CAS_21906
NSC_21906
AKOS026750058
PB32127
SB10317
NCGC00015249-02
NCGC00015249-03
NCGC00093739-01
NCGC00093739-02
NCGC00093739-03
NCGC00093739-05
NCGC00093739-06
NCGC00093739-07
NCGC00093739-09
NCGC00093739-10
NCGC00094632-01
NCGC00094632-02
BP-21994
LS-13784
DB-070947
NS00075577