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Metronidazole

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Identification
Molecular formula
C4H6N3O2
CAS number
443-48-1
IUPAC name
1-methyl-5-nitro-imidazole
State
State

At room temperature, Metronidazole is in a solid state. It is typically stored as a powder, which is then formulated into various pharmaceutical forms such as tablets or injections.

Melting point (Celsius)
159.00
Melting point (Kelvin)
432.15
Boiling point (Celsius)
104.50
Boiling point (Kelvin)
377.65
General information
Molecular weight
113.11g/mol
Molar mass
113.1120g/mol
Density
1.4778g/cm3
Appearence

Metronidazole is usually encountered as a white to pale yellow, crystalline powder. It is odorless and has a bitter taste. The compound is stable under normal conditions and is also known for its UV fluorescence property.

Comment on solubility

Solubility of 1-methyl-5-nitro-imidazole

1-methyl-5-nitro-imidazole, a chemical compound with the molecular formula C6H7N3O2, exhibits interesting solubility properties that are worth noting. While specific solubility data may vary depending on the source, we can summarize its behavior in various solvents:

  • Water Solubility: 1-methyl-5-nitro-imidazole shows limited solubility in water, making it less favorable for applications requiring aqueous solutions.
  • Organic Solvents: This compound tends to be more soluble in organic solvents such as ethanol and dimethyl sulfoxide (DMSO), which can facilitate its use in various chemical reactions and syntheses.
  • Temperature Effects: The solubility of 1-methyl-5-nitro-imidazole may slightly increase with temperature, a common characteristic of many organic compounds.

Understanding the solubility of this compound is essential for researchers and chemists, as it influences its applications in fields such as pharmaceuticals and biochemistry. Always consider performing solubility tests when working with new compounds to determine optimal solvent conditions.

Interesting facts

Interesting Facts About 1-Methyl-5-nitro-imidazole

1-Methyl-5-nitro-imidazole is a fascinating compound with notable applications and characteristics. Here are some captivating insights into this compound:

  • Pharmaceutical Significance: It is primarily recognized as an intermediate in the synthesis of various pharmaceutical products, including medicinal therapies for infections.
  • Biological Activity: The compound exhibits significant antibacterial and antifungal properties, making it a valuable tool in treating diverse infections.
  • Synthetic Versatility: Its structure allows for varied synthetic modifications, enabling chemists to develop new analogs that may enhance efficacy or reduce side effects.
  • Mechanistic Insights: Research suggests that the nitro group plays a critical role in the compound's biological activity, potentially affecting DNA synthesis in target microorganisms.
  • Environmental Stability: Studies indicate that this compound has a relative stability under different environmental conditions, which is pertinent for its storage and usage in pharmaceutical applications.

In summary, 1-Methyl-5-nitro-imidazole is more than just a chemical entity; its implications in medicine and synthetic chemistry make it an exciting subject for further research and development. As chemists delve into its properties and reactions, the potential for new therapeutic agents continues to expand.

Synonyms
1-METHYL-5-NITROIMIDAZOLE
1-Methyl-5-nitro-1H-imidazole
1H-Imidazole, 1-methyl-5-nitro-
Imidazole, 1-methyl-5-nitro-
BRN 0123550
UNII-LR2H69GV4P
EINECS 221-225-2
LR2H69GV4P
5-nitro-1-methylimidazole
DTXSID10184426
5-23-04-00481 (Beilstein Handbook Reference)
METHYL-5-NITROIMIDAZOLE, 1-
DTXCID20106917
jlzxsfpsjjmrix-uhfffaoysa-n
3034-42-2
MFCD00126968
1-Methyl-5-nitro-1H-imidazole;
CHEMBL454026
SCHEMBL3971243
AKOS000506062
CS-W002392
GS-6260
SB36477
AC-28876
SY017081
DB-082070
NS00028901
EN300-97223
1-Methyl-5-nitroimidazole, >97.0% (HPLC)
Q27283139
Z1255415727