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1-methyl-6-(trifluoromethyl)quinolin-2-one

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Identification
Molecular formula
C11H8F3NO
CAS number
458-29-7
IUPAC name
1-methyl-6-(trifluoromethyl)quinolin-2-one
State
State

At room temperature, 1-methyl-6-(trifluoromethyl)quinolin-2-one is in a solid state.

Melting point (Celsius)
100.50
Melting point (Kelvin)
373.65
Boiling point (Celsius)
370.00
Boiling point (Kelvin)
643.15
General information
Molecular weight
241.21g/mol
Molar mass
241.2050g/mol
Density
1.4100g/cm3
Appearence

The compound appears as a solid with crystalline form. It typically exhibits a light yellow color.

Comment on solubility

Solubility of 1-methyl-6-(trifluoromethyl)quinolin-2-one

The solubility of 1-methyl-6-(trifluoromethyl)quinolin-2-one is an intriguing aspect of its chemical behavior, influenced by its unique structural properties. Here’s what you need to know:

  • Polarity: The presence of the trifluoromethyl group enhances the overall polar character of the molecule, which can affect its interaction with solvent molecules.
  • Solvent Dependence: Generally, compounds like 1-methyl-6-(trifluoromethyl)quinolin-2-one exhibit variable solubility in solvents based on their polarity. For instance:
    • Polar solvents (such as water or alcohols): May show limited solubility due to the hydrophobic nature of the quinolinone structure.
    • Non-polar solvents (like hexane or chloroform): Typically, higher solubility can be observed, facilitating better solvation of the molecule.
  • Temperature Influence: The solubility may also increase at elevated temperatures, as molecular interactions are enhanced, allowing for better dispersion in various solvents.

In conclusion, while the exact solubility of 1-methyl-6-(trifluoromethyl)quinolin-2-one may vary depending on the specific conditions, understanding these key factors is crucial for predicting its behavior in different chemical environments.

Interesting facts

Interesting Facts about 1-methyl-6-(trifluoromethyl)quinolin-2-one

1-methyl-6-(trifluoromethyl)quinolin-2-one is an intriguing compound that belongs to the family of quinolones, which are well-known for their diverse biological and chemical properties. Here are some fascinating aspects of this compound:

  • Structure and Stability: The presence of a trifluoromethyl group contributes to the compound's unique structural characteristics, enhancing its stability and lipophilicity.
  • Biological Activity: Compounds related to the quinoline structure, such as this one, often exhibit important pharmacological properties. They have been studied for their potential use as antibacterial, antifungal, and anti-inflammatory agents.
  • Fluorine's Effect: The trifluoromethyl group can influence the electronic properties of the molecule, which may help in altering the binding interactions in biological systems or during chemical reactions.
  • Applications: Beyond biological applications, such compounds are explored in the development of materials science and may serve as fluorescent probes due to their distinct electronic properties.

As noted by researchers, "The versatility of quinoline derivatives in medicinal chemistry cannot be overstated." This highlights the importance of compounds like 1-methyl-6-(trifluoromethyl)quinolin-2-one in ongoing research and innovation.

With its distinctive features, this compound provides an exciting opportunity for scientists to explore its potential in various fields, making it a noteworthy topic in the study of chemical compounds.

Synonyms
FLUCARBRIL
2261-94-1
Flucarbril [INN]
flucarbrilo
UNII-5XJK6U3H0P
5XJK6U3H0P
1-Methyl-2-oxo-6-(trifluoromethyl)quinoline
DTXSID10177131
flucarbrilum
DTXCID3099622
1-methyl-6-(trifluoromethyl)quinolin-2-one
SCHEMBL2109672
CHEMBL2107392
BSFJLMNFTBGXQE-UHFFFAOYSA-N
Carbostyril, N-methyl-6-(trifluoromethyl)-
NS00120509
Q27263013