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Erythromycin

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Identification
Molecular formula
C37H67NO13
CAS number
114-07-8
IUPAC name
[1-methyl-7-oxo-6-[(3,4,5-trihydroxy-2-methoxy-8-methyl-non-6-enoyl)amino]azepan-3-yl] tetradecanoate
State
State

At room temperature, erythromycin is usually in the form of a crystalline, solid powder and is often formulated into tablets, capsules, and topical solutions for medical use.

Melting point (Celsius)
135.00
Melting point (Kelvin)
408.15
Boiling point (Celsius)
176.00
Boiling point (Kelvin)
449.15
General information
Molecular weight
733.94g/mol
Molar mass
733.9370g/mol
Density
1.1800g/cm3
Appearence

Erythromycin typically appears as a white or slightly yellow crystalline powder. It is often available in both anhydrous and hydrate forms, with the monohydrate being more common for certain pharmaceutical formulations.

Comment on solubility

Solubility of 1-methyl-7-oxo-6-[(3,4,5-trihydroxy-2-methoxy-8-methyl-non-6-enoyl)amino]azepan-3-yl tetradecanoate

The solubility of the compound 1-methyl-7-oxo-6-[(3,4,5-trihydroxy-2-methoxy-8-methyl-non-6-enoyl)amino]azepan-3-yl tetradecanoate, with the chemical formula C37H67NO13, is influenced by its unique structural features. This compound includes an array of functional groups which can significantly affect its interaction with solvents.

Factors Influencing Solubility:

  • Hydrophilic groups: The presence of multiple hydroxyl (-OH) groups contributes to increased solubility in polar solvents such as water.
  • Hydrophobic regions: The tetradecanoate tail (fatty acid chain) is inherently hydrophobic, potentially decreasing solubility in water but enhancing solubility in non-polar solvents.
  • Solvent polarity: The solubility can vary dramatically with the polarity of the solvent used. For example, this compound might show improved solubility in organic solvents like ethanol or methanol compared to pure water.

In summary, this compound's solubility profile is likely to be complex, reflecting the balance between its hydrophilic and hydrophobic characteristics. According to general solubility principles, "like dissolves like," which suggests that while it may have some solubility in water due to its hydroxyl groups, it will likely demonstrate a greater affinity for organic solvents due to its fatty acid component. Understanding these solubility dynamics is crucial for practical applications in formulations and synthesis.

Interesting facts

Interesting Facts about 1-Methyl-7-oxo-6-[(3,4,5-trihydroxy-2-methoxy-8-methyl-non-6-enoyl)amino]azepan-3-yl] Tetradecanoate

This intriguing compound belongs to a class known as bioactive lipids, showcasing a diverse range of structural characteristics that underline its potential in various applications. Here are some key insights:

  • Complex Structure: The compound features a unique azepan ring, a seven-membered cyclic amine, which contributes to its complex behavior and interactions within biological systems.
  • Functional Groups: The presence of multiple functional groups, including a ketone and amine, enhances its reactivity and potential biological activity, making it a candidate for research in pharmacology.
  • Natural Source: Similar structures are often found in natural products, particularly those derived from plants and marine organisms, suggesting a potential role in therapeutic applications or dietary benefits.
  • Potential Health Benefits: The trihydroxy component hints at antioxidant properties, which could play a significant role in combating oxidative stress in cells.
  • Research Interest: Due to its complex pharmacophore, this compound is an exciting subject for medicinal chemistry, particularly in drug design aimed at targeting specific biological pathways.

As noted by researchers, "The intricate architecture of such compounds often dictates their biological activity, paving the way for novel therapeutic strategies." Thus, studying 1-methyl-7-oxo-6-[(3,4,5-trihydroxy-2-methoxy-8-methyl-non-6-enoyl)amino]azepan-3-yl] tetradecanoate not only reveals the richness of chemical diversity but also highlights the ongoing quest for new medications derived from nature.