Skip to main content

Quaternary Ammonium Chloride

ADVERTISEMENT
Identification
Molecular formula
C16H18ClN
CAS number
.[1912-73-8]
IUPAC name
1-methyl-7-phenyl-3,4-dihydroisoquinolin-2-ium;chloride
State
State

At room temperature, this compound is found in the solid state. It is stable and non-volatile under standard laboratory conditions, making it easy to handle and store.

Melting point (Celsius)
82.00
Melting point (Kelvin)
355.15
Boiling point (Celsius)
305.00
Boiling point (Kelvin)
578.15
General information
Molecular weight
277.78g/mol
Molar mass
277.7780g/mol
Density
1.1592g/cm3
Appearence

This compound typically appears as a crystalline solid. It may form white, off-white, or colorless crystals depending on the level of purity and specific environmental conditions present during crystallization.

Comment on solubility

Solubility of 1-methyl-7-phenyl-3,4-dihydroisoquinolin-2-ium;chloride

The solubility of 1-methyl-7-phenyl-3,4-dihydroisoquinolin-2-ium;chloride can be intriguing, given its unique structure. As a quaternary ammonium compound, its solubility is influenced by several factors.

Key Factors Influencing Solubility:

  • Ionic Nature: Being a chloride salt, it is generally soluble in polar solvents such as water due to the ionic interaction with water molecules.
  • Hydrophobic Groups: The presence of the phenyl group introduces hydrophobic characteristics that may limit its solubility in highly polar solvents.
  • Temperature: Like many ionic compounds, solubility may increase with temperature, reflecting the general trend observed in solubility behavior.

In practical terms, one could expect 1-methyl-7-phenyl-3,4-dihydroisoquinolin-2-ium;chloride to be:

  • Soluble in water to a moderate extent
  • More soluble in organic solvents such as ethanol and acetone due to its hydrophobic regions

As with many compounds of this nature, it showcases a balance between hydrophilicity and hydrophobicity. Observations suggest that in dilute solutions, the solubility will vary significantly based on solvent choice and environmental conditions.

Interesting facts

Interesting Facts about 1-methyl-7-phenyl-3,4-dihydroisoquinolin-2-ium;chloride

The compound 1-methyl-7-phenyl-3,4-dihydroisoquinolin-2-ium;chloride is a fascinating member of the isoquinoline family, which has garnered significant interest in the fields of medicinal chemistry and drug design. Here are some intriguing aspects of this compound:

  • Structural Features: This compound features a dihydroisoquinoline skeleton, characterized by a fused bicyclic ring system. This structural configuration often contributes to unique pharmacological properties.
  • Biological Significance: Isoquinoline derivatives have been shown to possess a variety of biological activities, including antimicrobial, antioxidant, and anticancer properties. This makes them a potential target for drug development.
  • Quaternization: The presence of the quaternary ammonium ion in this compound indicates enhanced solubility in biological systems and potential applications in drug formulation and delivery systems.
  • Research Applications: Scientists are continuously investigating the pharmacological utilities of isoquinoline derivatives, aiming to develop novel therapeutic agents for diseases such as cancer, Alzheimer’s, and various infections.

As a synthesis chemist or pharmacologist, you might find the synthetic pathways leading to the production of this compound to be particularly intriguing. Understanding the reactivity of isoquinoline structures allows chemists to design new derivatives with tailored properties.
In the words of a seasoned chemist, "Every new compound we synthesize is a new story waiting to be told, revealing its secrets through interaction with biological systems." By studying compounds like 1-methyl-7-phenyl-3,4-dihydroisoquinolin-2-ium;chloride, we deepen our understanding of chemical diversity and its impact on health and disease.

Synonyms
24464-15-1
ISOQUINOLINE, 3,4-DIHYDRO-1-METHYL-6-PHENYL-, HYDROCHLORIDE
RefChem:1087765
1-Methyl-6-phenyl-3,4-dihydroisoquinoline hydrochloride