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1-Methyl-8-phenyl-3,4-dihydroisoquinoline

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Identification
Molecular formula
C16H17N
CAS number
1007-12-9
IUPAC name
1-methyl-8-phenyl-3,4-dihydroisoquinoline
State
State

At room temperature, 1-methyl-8-phenyl-3,4-dihydroisoquinoline exists in a solid state.

Melting point (Celsius)
108.00
Melting point (Kelvin)
381.15
Boiling point (Celsius)
410.00
Boiling point (Kelvin)
683.15
General information
Molecular weight
233.31g/mol
Molar mass
233.3120g/mol
Density
1.0823g/cm3
Appearence

1-Methyl-8-phenyl-3,4-dihydroisoquinoline typically appears in the form of a crystalline solid. The specifics of its appearance, such as color or texture, can vary depending on its purity and the presence of any impurities or solvates.

Comment on solubility

Solubility of 1-methyl-8-phenyl-3,4-dihydroisoquinoline

1-methyl-8-phenyl-3,4-dihydroisoquinoline is a member of the isoquinoline family, and its solubility characteristics are influenced by several factors. Understanding these factors can be pivotal for its applications in pharmaceuticals and organic chemistry.

Factors Affecting Solubility

The solubility of this compound can generally be influenced by:

  • Polarity: The presence of the methyl and phenyl groups can affect how polar or non-polar the molecule is, which in turn influences its solubility in different solvents.
  • Solvent Nature: This compound's solubility will vary significantly between organic solvents like ethanol or dichloromethane and polar solvents like water.
  • Temperature: Higher temperatures can often increase the solubility of organic compounds in solvents.

General Observations

Typically, compounds like 1-methyl-8-phenyl-3,4-dihydroisoquinoline are less soluble in water due to their overall non-polar characteristics but may exhibit moderate solubility in organic solvents. It is often important to empirically determine solubility for specific applications, especially in biological systems.


In summary, while the solubility of 1-methyl-8-phenyl-3,4-dihydroisoquinoline can be anticipated based on its molecular structure, detailed studies are essential for practical applications in various chemical environments.

Interesting facts

Interesting Facts about 1-methyl-8-phenyl-3,4-dihydroisoquinoline

1-methyl-8-phenyl-3,4-dihydroisoquinoline is a fascinating compound that belongs to the isoquinoline family, which has intrigued chemists and pharmacologists alike due to its diverse applications. Here are some key points about this compound:

  • Structural Diversity: The dihydroisoquinoline structure allows for various substituents, making this compound a versatile scaffold for drug development and molecular modification.
  • Biological Significance: Compounds similar to 1-methyl-8-phenyl-3,4-dihydroisoquinoline have shown biological activity in medicinal chemistry, particularly in the realms of neuropharmacology and oncology.
  • Potential Therapeutic Uses: Research suggests that derivatives of 1-methyl-8-phenyl-3,4-dihydroisoquinoline may have pharmacological effects, potentially acting as neuroprotective agents or affecting various neurotransmitter systems.
  • Research Interests: Scientists are investigating synthetic routes to produce this compound efficiently, as well as characterizing its interactions and reactivity with biological targets.

Overall, while it may not be as widely known as some other compounds, the study of 1-methyl-8-phenyl-3,4-dihydroisoquinoline opens doors to new discoveries in both chemical synthesis and pharmaceutical development. As one researcher put it, “The beauty of molecular scaffolds like this lies in their potential to unlock a wealth of biological knowledge.”

Synonyms
1-methyl-8-phenyl-3,4-dihydroisoquinoline
DTXSID90947359
RefChem:1055831
DTXCID701375619
24464-44-6
BRN 1572681
5-20-08-00293 (Beilstein Handbook Reference)