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9-Aminoacridine

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Identification
Molecular formula
C14H12N2
CAS number
90-45-9
IUPAC name
1-methylacridin-9-amine
State
State

At room temperature, 9-aminoacridine is a solid compound with a crystalline structure.

Melting point (Celsius)
213.00
Melting point (Kelvin)
486.00
Boiling point (Celsius)
553.00
Boiling point (Kelvin)
826.00
General information
Molecular weight
194.25g/mol
Molar mass
194.2460g/mol
Density
1.1633g/cm3
Appearence

9-Aminoacridine appears as yellow to orange crystalline powder. It is known for its bright orangish color which becomes evident when the crystals are viewed under natural light.

Comment on solubility

Solubility of 1-methylacridin-9-amine

The solubility of 1-methylacridin-9-amine can significantly impact its application and usability in various chemical and biochemical settings. Understanding its solubility behavior is crucial for processes such as formulation and synthesis.

Factors Affecting Solubility

Several factors can influence the solubility of 1-methylacridin-9-amine:

  • Polarity: The compound’s molecular structure dictates its polarity, which in turn affects its interactions with solvents.
  • Temperature: Generally, solubility increases with temperature for most solids.
  • pH of the solvent: As an amine, alterations in pH can lead to protonation, thus influencing solubility in aqueous solutions.

Solvent Compatibility

1-methylacridin-9-amine exhibits varying solubility in different solvents, which can be categorized as:

  • Polar solvents: Typically, compounds like this one show increased solubility in polar solvents such as water or alcohols.
  • Non-polar solvents: Its solubility may be lower in non-polar solvents due to the lack of proper interactions.

In general, its solubility characteristics are essential for effective utilization, highlighting the compound’s versatility across diverse applications.
Understanding these solubility aspects allows for optimized use in both laboratory and industrial settings.

Interesting facts

Interesting Facts about 1-Methylacridin-9-amine

1-Methylacridin-9-amine is a fascinating compound that belongs to the acridine family, known for its vivid aromaticity and biological significance. Here are some noteworthy points about this compound:

  • Biological Activity: Compounds in the acridine family are often studied for their potential anti-cancer properties. 1-Methylacridin-9-amine has shown promise in various biological applications, including its role as a fluorescent probe in biological imaging.
  • Structural Features: The unique structure of 1-Methylacridin-9-amine, characterized by its fused ring system, contributes to its photophysical properties, making it a subject of interest in the field of organic electronics.
  • Application in Pharmaceuticals: The compound has implications in drug development, especially in targeting specific pathways associated with cancer and other diseases through its amino group, which can participate in further chemical modifications.
  • Synthesis Routes: Various synthetic methods lead to the formation of 1-Methylacridin-9-amine, showcasing the versatility of organic synthesis techniques. This includes cyclization reactions and functional group transformations that can yield different derivatives.
  • Research Potential: Ongoing research investigates the compound's interaction with biological macromolecules, such as DNA and proteins, which could unlock new therapeutic potentials.

In summary, 1-Methylacridin-9-amine is not just an ordinary aromatic compound; it embodies a blend of structural elegance and functional promise that keeps scientists intrigued. As quoted by renowned chemist Robert H. Grubbs, "The best research is done at the intersection of disciplines." This compound exemplifies such a cross-disciplinary approach, marrying organic chemistry with biological sciences in the quest for new innovations.

Synonyms
23045-11-6
9-Amino-1-methyl-acridine
ACRIDINE, 9-AMINO-1-METHYL-
BRN 0160159
5-Amino-4-methylacridine (European)
DTXSID60177606
4-21-00-04250 (Beilstein Handbook Reference)
RefChem:317137
DTXCID80100097
1-methylacridin-9-amine
SCHEMBL11052646