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1-Methylindole

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Identification
Molecular formula
C9H9N
CAS number
603-76-9
IUPAC name
1-methylindole
State
State

At room temperature, 1-Methylindole exists as a solid which may manifest as slightly yellow crystals.

Melting point (Celsius)
-20.00
Melting point (Kelvin)
253.15
Boiling point (Celsius)
253.00
Boiling point (Kelvin)
526.15
General information
Molecular weight
131.18g/mol
Molar mass
131.1780g/mol
Density
1.0814g/cm3
Appearence

1-Methylindole appears as a yellow solid at room temperature, which can also appear as a pale yellow liquid when slightly melted. The compound is known for its distinctive aromatic odor.

Comment on solubility

Solubility of 1-methylindole

1-methylindole, known for its unique aromatic structure, presents intriguing solubility characteristics. Solubility is fundamentally influenced by the compound's structure, polarity, and the nature of the solvent. In the case of 1-methylindole, we can observe the following key points:

  • Polarity: 1-methylindole is a relatively non-polar compound due to its aromatic ring structure and the presence of the methyl group. This non-polar nature influences its solubility in various solvents.
  • Solvent Compatibility: It tends to be more soluble in non-polar organic solvents such as benzene, toluene, and chloroform, while it shows limited solubility in polar solvents like water.
  • Temperature Effects: The solubility of 1-methylindole can increase with rising temperatures, which commonly holds true for many organic compounds.

In conclusion, understanding the solubility of 1-methylindole is crucial for its application in various fields of chemistry. As the solubility varies significantly based on the solvent and temperature, it illustrates the importance of considering these factors when working with this compound.

Interesting facts

Interesting Facts About 1-Methylindole

1-Methylindole, also known as 1-methyl-1H-indole, is a fascinating compound with various implications in chemical and biological systems. This compound falls under the indole category, which has served as a crucial framework in the development of numerous pharmaceuticals and organic materials. Here are some intriguing points about 1-methylindole:

  • Molecular Structure: The structure of 1-methylindole features a methyl group attached to the nitrogen atom of the indole ring, which is essential for determining its reactivity and interaction with biological systems.
  • Biological Activities: Compounds related to indole, including 1-methylindole, have shown varied biological activities. They are often studied for their anti-cancer properties and potential influence on serotonin receptors.
  • Odor and Flavor: Interestingly, 1-methylindole contributes to the aromatic scent found in certain flowers and is detected in various perfumes and flavorings, enhancing sensory experiences.
  • Presence in Nature: It occurs naturally in bodily fluids, such as sweat and urine, primarily due to the metabolic activity of gut bacteria, providing insight into human biology and health.
  • Applications: The compound’s derivatives are investigated in pharmacology and materials science, paving the way for novel drug development and organic electronic applications.

As with many organic compounds, understanding 1-methylindole requires an appreciation for its chemistry and the biological contexts in which it operates. In Jongewaard's words, "Every molecule tells a story, and 1-methylindole is no exception." This reflects the significant interplay between chemistry and life, emphasizing the importance of studying compounds like 1-methylindole.

Synonyms
1-METHYLINDOLE
1-Methyl-1H-indole
N-Methylindole
1H-Indole, 1-methyl-
Indole, 1-methyl-
1-Methylindole (N-)
UNII-8H698ROJ5F
NSC 212534
8H698ROJ5F
EINECS 210-057-5
NSC-212534
DTXSID3060534
NMethylindole
1Methyl1Hindole
Indole, 1methyl
1HIndole, 1methyl
Indole, 1methyl (8CI)
Indole, 1-methyl-(8CI)
DTXCID5042792
210-057-5
blrhmmgncxnxjl-uhfffaoysa-n
inchi=1/c9h9n/c1-10-7-6-8-4-2-3-5-9(8)10/h2-7h,1h
603-76-9
1-Methyl-1H-indole-2-D
1-Methyl-1H-indole-4-D
1-Methyl-1H-indole-5-D
1-Methyl-1H-indole-6-D
1-Methyl-1H-indole-7-D
N-methyl indole
MFCD00005800
CHEMBL19912
1884330-89-5
2122799-79-3
2122799-80-6
2241982-98-7
857380-47-3
methylindole
N-methylindol
1-methyl indole
1-methyl-indole
N- methyl indole
MFCD31699943
MFCD31699944
MFCD31699945
MFCD31699946
MFCD31699947
1-Methylindole, >=97%
SCHEMBL29812
BCP26400
HY-Y1162
BBL100303
BDBM50098763
NSC212534
STL553897
AKOS005198531
CS-W008981
FM11783
PB48626
AC-19059
AS-11848
SY246277
SY246324
SY246325
SY246326
SY246327
DB-011620
M0561
NS00034347
EN300-21605
F11257
doi:10.14272/BLRHMMGNCXNXJL-UHFFFAOYSA-N.1
Q4545796
1-Methyl-1H-indole; N-Methylindole; NSC 212534;
F0001-1582
Z104504048