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1-Methylindoline-2-thione

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Identification
Molecular formula
C9H9NS
CAS number
3135-68-2
IUPAC name
1-methylindoline-2-thione
State
State

At room temperature, 1-Methylindoline-2-thione is in a solid state, typically forming crystalline structures.

Melting point (Celsius)
132.00
Melting point (Kelvin)
405.15
Boiling point (Celsius)
330.00
Boiling point (Kelvin)
603.15
General information
Molecular weight
163.24g/mol
Molar mass
163.2430g/mol
Density
1.1987g/cm3
Appearence

1-Methylindoline-2-thione typically appears as a yellow to yellow-orange crystalline powder. It may have a distinctive odor that is characteristic of sulfur-containing organic compounds.

Comment on solubility

Solubility of 1-methylindoline-2-thione

1-methylindoline-2-thione is an intriguing compound when it comes to its solubility characteristics. Understanding its solubility can help in various applications, including synthetic processes and pharmaceutical formulations.

Key Points about Solubility:

  • Solvent Compatibility: The solubility of 1-methylindoline-2-thione tends to be higher in polar organic solvents, such as dimethyl sulfoxide (DMSO) and ethanol, compared to non-polar solvents.
  • Hydrophilicity vs. Hydrophobicity: The presence of sulfur in the thione group imparts some polar characteristics, making the compound somewhat soluble in water, but it still exhibits mostly hydrophobic behavior.
  • Concentration Effects: As with many organic compounds, solubility can be influenced by temperature and concentration. Increasing the temperature typically enhances solubility.
  • pH Influence: The solubility may vary with changes in pH due to the formation of different ionic species or complexes in solutions.

In summary, while 1-methylindoline-2-thione shows **moderate solubility** in certain solvents, the specific conditions of solubility can significantly affect its behavior in applications. It is essential to consider these factors when working with this compound.

Interesting facts

Interesting Facts about 1-Methylindoline-2-thione

1-Methylindoline-2-thione is a fascinating compound that belongs to the family of indoline derivatives—a class of organic compounds known for their unique structural properties and diverse applications.

Key Characteristics

  • Structure and Functionality: The indoline core provides this compound with a distinctive scaffold that allows for interesting chemical reactivity. The presence of a thione (-S=) group enhances its potential as a nucleophile, enabling various synthetic transformations.
  • Bioactivity: Compounds like 1-Methylindoline-2-thione have garnered interest in medicinal chemistry. They potentially exhibit antimicrobial and antitumor activities, making them targets for further pharmaceutical research.
  • Applications: Beyond its biological relevance, this compound can also be utilized in the development of organic materials, such as light-emitting diodes (LEDs) and solar cells, due to its electronic properties.

Research and Significance

Research on 1-Methylindoline-2-thione continues to expand, as scientists explore its potential in photochemical reactions and as a fluorescent probe in various sensing applications. This positions the compound at the intersection of organic chemistry and materials science.

Noteworthy Insights

As we look to the future, the study of indoline derivatives like 1-Methylindoline-2-thione uncovers new methodologies in synthetic organic chemistry, revealing innovative pathways for the synthesis of complex molecules.

In summary, the diverse chemical properties and potential applications of 1-Methylindoline-2-thione make it a compound of great interest for both chemists and researchers across various scientific disciplines. Its journey from a simple molecule to a potential powerhouse in research illustrates the endless possibilities within the world of chemistry!

Synonyms
1,3-Dihydro-1-methyl-2H-indole-2-thione
1-methyl-2,3-dihydro-1H-indole-2-thione
968-911-4
13637-38-2
1-Methylindoline-2-thione
2-INDOLINETHIONE, 1-METHYL-
1-methyl-3H-indole-2-thione
1-Methyl-2-indolinethione
2H-Indole-2-thione, 1,3-dihydro-1-methyl-
1-METHYL-1,3-DIHYDRO-INDOLE-2-THIONE
BRN 1526437
N-methyl thio-oxindole
SCHEMBL8999008
DTXSID80159767
GBSPZRWQIJCQQB-UHFFFAOYSA-N
AKOS006276816
CS-0300848
EN300-79104
H20226