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Isatin

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Identification
Molecular formula
C8H5NO2
CAS number
91-56-5
IUPAC name
1-methylindoline-2,3-dione
State
State

At room temperature, isatin is in a solid state. It is relatively stable and has a distinct crystalline structure, making it a solid under typical laboratory conditions.

Melting point (Celsius)
200.00
Melting point (Kelvin)
473.15
Boiling point (Celsius)
307.00
Boiling point (Kelvin)
580.15
General information
Molecular weight
147.14g/mol
Molar mass
147.1410g/mol
Density
1.3080g/cm3
Appearence

Isatin is typically a yellow to orange crystalline solid. It is known for its distinctive orange coloration and can appear in the form of shiny crystalline powder or larger crystals, depending on the form it is procured in. The solid tends to have a characteristic odor.

Comment on solubility

Solubility of 1-methylindoline-2,3-dione

1-methylindoline-2,3-dione, a compound characterized by its unique structure, exhibits specific solubility properties that are crucial for its application in various chemical processes. The solubility of this compound is influenced by several factors:

  • Polarity: As a polar molecule, 1-methylindoline-2,3-dione tends to dissolve well in polar solvents like water and alcohol.
  • Temperature: Increased temperature generally enhances solubility, allowing more of the compound to dissolve in solvents as kinetic energy increases.
  • Concentration: The solubility can vary based on the concentration of the compound already present in the solution, demonstrating that solubility is a dynamic equilibrium.

Additionally, it is essential to evaluate the pH of the solution, as certain functional groups within the molecule may affect solubility in acidic or basic conditions. Generally, 1-methylindoline-2,3-dione is described as moderately soluble in organic solvents, leading to a versatile use in synthesis and chemical reactions.

In summary, understanding the solubility characteristics of 1-methylindoline-2,3-dione allows chemists to predict its behavior in reactions and formulations effectively. Remember, "a compound's solubility is the gateway to its reactivity."

Interesting facts

Interesting Facts About 1-Methylindoline-2,3-dione

1-Methylindoline-2,3-dione is a fascinating organic compound belonging to the indoline family, which is recognized for its diverse applications in the fields of chemistry, materials science, and medicinal research. Here are some key highlights:

  • Unique Structure: This compound features a bicyclic indoline structure that is substituted at the nitrogen atom with a methyl group. This structural uniqueness often leads to interesting reactivity and properties.
  • Versatile Synthetic Intermediate: 1-Methylindoline-2,3-dione serves as an essential building block in organic synthesis. It is often used in the production of various drug candidates, dyes, and agrochemicals.
  • Biological Activity: Research has shown that compounds related to indoline-2,3-dione possess notable biological activities, including antioxidant, antimicrobial, and potential anticancer properties. This raises important questions about their mechanisms of action and therapeutic potential.
  • Colorimetric Applications: The property of this compound to exhibit distinct color changes upon reaction with various reagents makes it a useful tool in analytical chemistry for detecting specific ions or functional groups.

As you delve into the world of 1-methylindoline-2,3-dione, remember that even small changes in molecular structure can lead to significant variations in properties and applications. The study of such compounds not only enhances our understanding of chemical behavior but also paves the way for innovations in drug design and material sciences.

Quote: "In chemistry, the beauty lies in the connections between structure, properties, and reactivity, each compound telling its own unique story."

Synonyms
N-Methylisatin
1-Methylisatin
2058-74-4
1-Methyl-1H-indole-2,3-dione
1-methylindole-2,3-dione
1H-Indole-2,3-dione, 1-methyl-
1-Methyl-indole-2,3-dione
NSC 42449
INDOLE-2,3-DIONE, 1-METHYL-
OL-57
1-Methyl-2,3-dihydroindole-2,3-dione
EINECS 218-164-9
BRN 0128280
DTXSID80174591
5-21-10-00236 (Beilstein Handbook Reference)
DTXCID5097082
1H-Indole-2,3-dione, 1-methyl-(9CI)
218-164-9
1-methylindoline-2,3-dione
1-methyl-2,3-dihydro-1H-indole-2,3-dione
MFCD00005812
N-Methylindoline-2,3-dione
1-Methyl-2,3-indolinedione
CHEMBL60569
NSC-42449
N-methylindol-2,3-dione
N-methyl isatin
N-methyl isatine
CNV9DH4SXQ
1-Methylisatin, 97%
Indole-2, 1-methyl-
1H-Indole-2, 1-methyl-
SCHEMBL126628
Indole-2,3-dione, N-methyl-
BDBM10304
VCYBVWFTGAZHGH-UHFFFAOYSA-
OL 57
1H-Indole-2,3-dione,1-methyl-
ALBB-016867
NSC42449
BBL007926
FD7160
STK801660
AKOS000267191
FS-1270
SB66082
AC-26339
FM125542
HY-23148
SY048456
SY293688
DB-032067
CS-0045288
M2706
NS00026694
EN300-01050
M50049
AE-641/00185019
Z56869450
F0722-0740
N‐methylindol‐2,3‐dione (Compound 2)
InChI=1/C9H7NO2/c1-10-7-5-3-2-4-6(7)8(11)9(10)12/h2-5H,1H3