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1-Methylpiperidin-2-one

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Identification
Molecular formula
C6H11NO
CAS number
694-85-9
IUPAC name
1-methylpiperidin-2-one
State
State

At room temperature, 1-methylpiperidin-2-one is a liquid. Its relatively low melting point of -1°C indicates that it remains in liquid form well below standard room temperature.

Melting point (Celsius)
-1.00
Melting point (Kelvin)
272.15
Boiling point (Celsius)
206.00
Boiling point (Kelvin)
479.15
General information
Molecular weight
113.16g/mol
Molar mass
113.1580g/mol
Density
0.9826g/cm3
Appearence

1-Methylpiperidin-2-one is a colorless to pale yellow liquid. It is typically clear and exhibits a slight, amine-like odor. Though usually found in liquid form, impurities can sometimes give it a mild coloration.

Comment on solubility

Solubility of 1-Methylpiperidin-2-one

1-Methylpiperidin-2-one, with the chemical formula C6H11NO, exhibits interesting solubility properties that are worth discussing. Here are some key points regarding its solubility:

  • Solvent Compatibility: This compound is largely soluble in polar organic solvents such as ethanol and water, due to its nitrogen atom and the polar carbonyl group which can form hydrogen bonds.
  • Behavior in Non-Polar Solvents: Conversely, it shows reduced solubility in non-polar solvents, indicating that like dissolves like. This aligns with the principles of solubility where polar substances tend to dissolve better in polar solvents.
  • Temperature Effects: Solubility can also vary with temperature; typically, increasing temperature leads to an increase in solubility for solid solutes in liquid solvents.

In summary, 1-methylpiperidin-2-one's solubility characteristics reveal its affinity for polar environments, making it an interesting compound for various chemical applications.

Interesting facts

Interesting Facts about 1-Methylpiperidin-2-one

1-Methylpiperidin-2-one is a fascinating compound that has captured the attention of chemists and researchers alike for various reasons:

  • Structural Importance: This compound features a piperidinone structure, which is significant in medicinal chemistry. The piperidine ring is a common motif in many biologically active molecules.
  • Synthetic Utility: 1-Methylpiperidin-2-one serves as a crucial intermediate in the synthesis of various pharmaceuticals, enhancing its importance in the field of organic synthesis.
  • Biological Activity: Research indicates that derivatives of this compound can exhibit properties such as antidepressant and anxiolytic effects, making it a subject of interest in neuropharmacology.
  • Versatile Applications: Beyond pharmaceuticals, this compound is also used in the production of agrochemicals and as a solvent in various chemical reactions.
  • Research Potential: Ongoing studies on 1-Methylpiperidin-2-one aim to explore its potential in developing new therapeutic agents, highlighting its significance in drug discovery.

In conclusion, 1-Methylpiperidin-2-one is not just an ordinary chemical compound; it embodies a remarkable blend of structural characteristics and practical applications that continue to inspire scientific inquiry. As research progresses, this compound may further our understanding of its biological implications and potential therapeutic benefits, reminding us how chemistry can impact the world.

Synonyms
1-Methyl-2-piperidone
931-20-4
N-Methyl-2-piperidone
2-Piperidinone, 1-methyl-
1-Methyl-2-piperidinone
2-Piperidone, 1-methyl-
N-Methylvalerolactam
1-Methylpiperidine-2-one
N-METHYL-2-PIPERIDINONE
NSC 67384
EINECS 213-231-9
BRN 0001708
AI3-11535
1T6L7S01J4
NSC-67384
DTXSID7061308
5-21-06-00398 (Beilstein Handbook Reference)
DTXCID4048854
1-Methylpiperidin-2-one
N-methylpiperidone
1-Methyl-piperidin-2-one
N-Methyl-.delta.-valerolactam
MFCD00006555
UNII-1T6L7S01J4
1-methylpiperidone
N-methyl piperidone
N-methyl-piperidone
1-methyl-piperidone
1-Methyl piperidone
N-methylpiperidin-2-one
2-Piperidinone,1-methyl-
CHEMBL12011
SCHEMBL120927
N-Methyl-2-piperidone, 99%
AKOS015905376
FS-5066
SB41397
SY031205
DB-057371
CS-0222604
NS00039525
EN300-111902
A859866
Q27252857
InChI=1/C6H11NO/c1-7-5-3-2-4-6(7)8/h2-5H2,1H