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1-Methylpiperidine

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Identification
Molecular formula
C6H13N
CAS number
626-67-5
IUPAC name
1-methylpiperidine
State
State

At room temperature, 1-methylpiperidine is in a liquid state.

Melting point (Celsius)
-8.00
Melting point (Kelvin)
265.15
Boiling point (Celsius)
106.00
Boiling point (Kelvin)
379.15
General information
Molecular weight
99.18g/mol
Molar mass
99.1750g/mol
Density
0.8385g/cm3
Appearence

1-Methylpiperidine is a clear colorless liquid. It has a characteristic amine-like odor and is miscible with water as well as many organic solvents.

Comment on solubility

Solubility of 1-methylpiperidine

1-methylpiperidine, a heterocyclic organic compound, exhibits interesting solubility characteristics that are noteworthy. Its solubility is generally influenced by several factors including polarity and the presence of functional groups. Here are some key points regarding its solubility:

  • Polar Nature: 1-methylpiperidine is a polar compound due to its nitrogen atom, which has a lone pair of electrons. This property enhances its ability to interact with polar solvents.
  • Water Solubility: While 1-methylpiperidine is soluble in water, the solubility is not as high as many ionic or highly polar compounds. This moderate solubility is largely attributed to its hydrophobic alkyl group which reduces the overall solubility in water.
  • Organic Solvents: It demonstrates good solubility in a variety of organic solvents such as ethanol, methanol, and acetone, making it versatile for various applications in organic synthesis.
  • Temperature Effects: As with many organic compounds, the solubility of 1-methylpiperidine may increase with temperature, allowing for greater dissolving capacity in warmer solutions.

In summary, while 1-methylpiperidine finds a comfortable balance in solubility across different solvents, the extent of this solubility largely depends on the solvent choice and environmental conditions. This compound is a fascinating case of how molecular structure influences solubility behavior.

Interesting facts

Interesting Facts about 1-Methylpiperidine

1-Methylpiperidine, a derivative of the piperidine ring, is an intriguing compound that falls within the category of cyclic amines. Here are some fascinating insights into its structure and applications:

  • Cyclic Structure: The compound features a six-membered ring with one nitrogen atom, contributing to its unique properties and reactivity. The presence of the methyl group enhances its steric properties.
  • Industrial Relevance: 1-Methylpiperidine is often utilized in the synthesis of various pharmaceuticals and agrochemicals. Its ability to act as a building block makes it essential in organic chemistry.
  • Drug Development: Researchers have studied 1-methylpiperidine for its potential as a pharmacophore in drug molecules, owing to its ability to interact with biological targets.
  • Properties and Variations: The presence of a methyl group modestly alters the properties of the piperidine ring, influencing its biological activity and physicochemical characteristics.
  • Research and Development: Scientists examine 1-methylpiperidine for applications in material science and catalysis, illustrating the compound's versatility beyond pharmaceuticals.

In summary, 1-methylpiperidine is not just a simple alkaloid; it is a vital component in modern chemistry, showcasing significant potential across various fields of study. As the great chemist Linus Pauling once stated, “The best way to have a good idea is to have a lot of ideas.” Exploring compounds like 1-methylpiperidine surely holds many possibilities for scientific advancement.

Synonyms
1-Methylpiperidine
N-METHYLPIPERIDINE
Piperidine, 1-methyl-
methylpiperidine
LK 20
EINECS 210-959-9
piperidine, 1-methyl
AI3-25263
617374QZN4
DTXSID8060822
UNII-617374QZN4
EC 210-959-9
UN 2399
DTXCID0043420
inchi=1/c6h13n/c1-7-5-3-2-4-6-7/h2-6h2,1h
pamiqikduotobw-uhfffaoysa-n
626-67-5
1-Methyl-piperidine
N-methyl piperidine
UN2399
methylpiperdine
1-methylpiperadine
N-methyl-piperidine
1-methyl piperidine
MFCD00006491
N-Methylpiperidine, 99%
1-Methylpiperidine, >=98%
CHEMBL281417
GTPL5522
SCHEMBL1220995
STR03153
PDSP1_001476
PDSP2_001460
AKOS015950624
FM36440
DB-002021
M0403
NS00007867
1-Methylpiperidine [UN2399] [Flammable liquid]
Q24004759