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2-Mercaptopyridine

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Identification
Molecular formula
C6H7NS
CAS number
1121-31-9
IUPAC name
1-methylpyridine-2-thione
State
State

At room temperature, 2-Mercaptopyridine is typically found in a solid state. It is crystalline in form and often appears as a yellow solid.

Melting point (Celsius)
62.00
Melting point (Kelvin)
335.15
Boiling point (Celsius)
63.00
Boiling point (Kelvin)
336.15
General information
Molecular weight
111.17g/mol
Molar mass
111.1680g/mol
Density
1.1840g/cm3
Appearence

2-Mercaptopyridine is a yellow crystalline solid. It has a distinct and characteristic odor. Upon exposure, it appears as light yellow to white crystals or a crystalline powder.

Comment on solubility

Solubility of 1-Methylpyridine-2-thione (C6H7NS)

1-Methylpyridine-2-thione is a compound that exhibits interesting solubility characteristics due to its unique molecular structure. Understanding the solubility of this compound is essential for various applications and chemical processes.

Key Solubility Properties:

  • Polar Nature: The presence of the thione group contributes to a degree of polarity, enhancing its solubility in polar solvents.
  • Solvent Compatibility: 1-methylpyridine-2-thione is typically soluble in:
    • Water
    • Alcohols (e.g., ethanol, methanol)
    • Common organic solvents such as DMSO and acetone
  • Limited Solubility: It may have limited solubility in non-polar solvents like hexane or benzene due to its polar functional groups.

In summary, the solubility of 1-methylpyridine-2-thione predominantly favors polar environments, making it useful in various chemical applications where such conditions are present. Its solubility profile is a testament to the intricate relationship between molecular structure and solubility behavior.

Interesting facts

Interesting Facts about 1-Methylpyridine-2-thione

1-Methylpyridine-2-thione is an intriguing compound that belongs to the family of thio-heterocycles, featuring a sulfur atom in its structure. It is characterized by the fusion of a methyl group with a pyridine ring, resulting in a unique set of chemical properties and applications. Here are some key insights:

  • Structural Curiosity: The presence of the thione group (-C=S) instead of the more common ketone or thol group is what gives this compound its particular reactivity and properties.
  • Biological Relevance: Compounds similar to 1-methylpyridine-2-thione often display biological activity, including antimicrobial properties, making them of interest in pharmaceutical research.
  • Chemical Reactivity: The 2-thione functionality lends itself to a wide range of chemical reactions, including nucleophilic substitutions and cyclization processes, which are crucial for the synthesis of more complex organic structures.
  • Solubility Insights: As a member of the pyridine family, it typically demonstrates diverse solubility characteristics, allowing for versatility in various solvents, which is essential for laboratory applications.
  • Legacy: Pyridine derivatives have a storied history in organic chemistry, with many compounds being explored for their potential as solvents, ligands in coordination complexes, and constituents in agrochemicals.

In summary, 1-methylpyridine-2-thione exemplifies how modifications to a basic ring structure can lead to compounds with both fascinating chemistry and significant practical applications. Its study continues to inspire chemists seeking to harness its properties for innovative uses in various fields.

Synonyms
1-methylpyridine-2-thione
N-Methyl-2-pyridinethione
1-Methyl-2-thiopyridone
2044-27-1
1-methylpyridine-2(1H)-thione
1-Methyl-2-pyridinethione
2(1H)-PYRIDINETHIONE, 1-METHYL-
1-Methyl-2(1H)-pyridinethione
N-Methylthiopyridone-2
8MG7JSX8JG
NSC-157922
N-Methylthiopyridone-2 [French]
NSC 157922
BRN 0107807
NSC157922
UNII-8MG7JSX8JG
5-21-07-00148 (Beilstein Handbook Reference)
N-methyl-1h-pyridine-2-thione
SCHEMBL7257017
1-Methyl-1H-pyridine-2-thione
DTXSID60870923
HMS1783C02
AKOS001060911
NCGC00340849-01
pyridine, 1,2-dihydro-1-methyl-2-thio-
DB-301558
AB01100313-03
AJ-333/25022007
Z56928900