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Diphenhydramine Hydrochloride

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Identification
Molecular formula
C17H21NO•HCl
CAS number
147-24-0
IUPAC name
(1-methylpyrrolidin-1-ium-2-yl)methyl 2,2-diphenyl-2-propoxy-acetate;chloride
State
State

At room temperature, diphenhydramine hydrochloride exists as a solid. The compound is usually marketed in powder form for medicinal uses.

Melting point (Celsius)
168.00
Melting point (Kelvin)
441.00
Boiling point (Celsius)
240.00
Boiling point (Kelvin)
513.00
General information
Molecular weight
291.82g/mol
Molar mass
291.8220g/mol
Density
1.0830g/cm3
Appearence

Diphenhydramine hydrochloride typically appears as a white crystalline powder. It is odorless and has a bitter taste. It is also slightly soluble in water and readily soluble in alcohol or glycol solvents.

Comment on solubility

Solubility of (1-methylpyrrolidin-1-ium-2-yl)methyl 2,2-diphenyl-2-propoxy-acetate;chloride

The solubility of the compound (1-methylpyrrolidin-1-ium-2-yl)methyl 2,2-diphenyl-2-propoxy-acetate;chloride can be assessed by considering several key factors:

  • Polarity: As a quaternary ammonium compound, it likely exhibits pronounced polarity due to the positively charged nitrogen atom which can enhance solubility in polar solvents.
  • Functional Groups: The presence of both an acetate and a chloride moiety suggests potential interactions with water, which may favor its solubility in aqueous solutions.
  • Hydrophobic Interactions: The aromatic groups (the diphenyl moiety) introduce hydrophobic characteristics that can impact its overall solubility in nonpolar solvents.
  • Temperature Influence: The solubility is also expected to be temperature-dependent, where higher temperatures generally increase solubility for many compounds.
  • pH Sensitivity: The solubility behavior might be influenced by the pH of the solution, particularly for compounds that can undergo protonation or deprotonation.

In summary, while it is likely that (1-methylpyrrolidin-1-ium-2-yl)methyl 2,2-diphenyl-2-propoxy-acetate;chloride has good solubility in polar solvents, its solubility in nonpolar solvents may be limited due to the presence of hydrophobic phenyl groups. Experimentally determined solubility values are essential to obtain a comprehensive understanding of its behavior in different environments.

Interesting facts

Interesting Facts about (1-methylpyrrolidin-1-ium-2-yl)methyl 2,2-diphenyl-2-propoxy-acetate; chloride

(1-methylpyrrolidin-1-ium-2-yl)methyl 2,2-diphenyl-2-propoxy-acetate; chloride is a fascinating compound with a variety of applications and unique characteristics. Here’s an overview of its significance:

  • Ion Exchange Properties: This compound belongs to the family of ionic liquids, known for their exceptional ion exchange properties which are crucial in many chemical reactions.
  • Room Temperature Liquid: It remains liquid at room temperature, making it an excellent solvent and medium for performing various chemical reactions without the need for heating or specialized equipment.
  • Wide Applications: Used in fields such as:
    • Electrochemistry: Serves as an electrolyte in batteries and supercapacitors.
    • Synthesis: Acts as a solvent and catalyst for organic reactions, offering a greener alternative to traditional solvents.
    • Biotechnology: Plays a role in drug delivery systems and as a medium for biological assays.
  • Stability and Safety: It exhibits remarkable thermal stability and low volatility, reducing health and environmental risks associated with traditional solvents.

In conclusion, (1-methylpyrrolidin-1-ium-2-yl)methyl 2,2-diphenyl-2-propoxy-acetate; chloride is not just a simple compound—it embodies the convergence of innovation and practicality in modern chemistry. Its properties make it a valuable tool in various scientific endeavors, making the study and application of this compound a captivating subject for both researchers and students alike.

Synonyms
Acetic acid, 2,2-diphenyl-2-propoxy-, (1-methyl-2-pyrrolidinyl)methyl ester, hydrochloride
3043-05-8
2,2-Diphenyl-2-propoxyacetic acid (1-methyl-2-pyrrolidinyl)methyl ester hydrochloride