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Tolterodine

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Identification
Molecular formula
C22H31NO2
CAS number
124937-52-6
IUPAC name
(1-methylpyrrolidin-3-yl)methyl N-(2,6-dimethylphenyl)carbamate
State
State

At room temperature, Tolterodine is found in a solid state as a crystalline powder.

Melting point (Celsius)
104.00
Melting point (Kelvin)
377.15
Boiling point (Celsius)
478.69
Boiling point (Kelvin)
751.84
General information
Molecular weight
325.50g/mol
Molar mass
325.4470g/mol
Density
1.0840g/cm3
Appearence

Tolterodine typically appears as a white crystalline powder.

Comment on solubility

Solubility of (1-methylpyrrolidin-3-yl)methyl N-(2,6-dimethylphenyl)carbamate

The solubility of (1-methylpyrrolidin-3-yl)methyl N-(2,6-dimethylphenyl)carbamate in various solvents reveals some interesting characteristics. Due to its structural components, this compound showcases both hydrophilic and hydrophobic traits, making it behave diversely in different environments.

Factors Influencing Solubility

  • Solvent Polarity: The solubility in polar solvents (e.g., water, alcohols) is generally limited compared to non-polar solvents (e.g., hexane, toluene) due to the presence of non-polar aromatic groups in its structure.
  • Hydrogen Bonding: The carbamate functional group can engage in hydrogen bonding, potentially increasing solubility in certain polar solvents.
  • Temperature: A rise in temperature often enhances solubility, particularly in solid forms, allowing for better dissolution in chosen solvents.

Furthermore, this compound's solubility must also be evaluated within the scope of its applications. As quoted, “Solubility is key to bioavailability,” implying that its behavior in various solvents could affect its efficacy in pharmacological applications.

In summary, while (1-methylpyrrolidin-3-yl)methyl N-(2,6-dimethylphenyl)carbamate may show modest solubility in some polar solvents, it generally favors non-polar environments, demonstrating a complex relationship influenced by its structural characteristics and the surrounding conditions.

Interesting facts

Interesting Facts about (1-methylpyrrolidin-3-yl)methyl N-(2,6-dimethylphenyl)carbamate

(1-methylpyrrolidin-3-yl)methyl N-(2,6-dimethylphenyl)carbamate is an intriguing compound that showcases the versatility of organic chemistry in pharmaceutical development. This compound exemplifies how various functional groups can be combined to create molecules with significant biological activity.

Key Highlights:

  • Pharmacological Relevance: This compound is known for its potential therapeutic applications. Its structure suggests it may interact with neural pathways, which could be crucial for the development of drugs aimed at treating neurological disorders.
  • Hybrid Structure: The presence of both a pyrrolidine ring and a carbamate moiety is particularly noteworthy. This hybrid structure can enhance the compound's ability to modulate biological targets, making it a subject of interest in medicinal chemistry.
  • Nature of the Substituents: The incorporation of a 2,6-dimethylphenyl group contributes to the compound's lipophilicity, potentially improving its bioavailability. This is critical in drug design, as it influences how well a substance can be absorbed and utilized by the body.
  • Research Potential: Scientists are continuously exploring this compound for its effects on various receptor sites, especially given its unique configuration that may allow for selective interactions at the molecular level.
  • Synthetic Routes: The synthesis of such compounds often involves multi-step organic reactions, which can be a fascinating area of study for chemistry students focused on synthetic methods.

In summary, the study of (1-methylpyrrolidin-3-yl)methyl N-(2,6-dimethylphenyl)carbamate underscores the innovation present in modern chemistry. As quoted in research literature, "The intricate dance of atoms and molecules holds the potential to unlock new frontiers in medicine." This compound is one of many that could pave the way for advancements in drug discovery and development.

Synonyms
(1-Methyl-3-pyrrolidinyl)methyl 2,6-dimethylcarbanilate
20930-81-8
BRN 1477795
DTXSID90943215
2,6-Dimethylcarbanilic acid (1-methyl-3-pyrrolidinyl)methyl ester
CARBANILIC ACID, 2,6-DIMETHYL-, (1-METHYL-3-PYRROLIDINYL)METHYL ESTER
(1-Methylpyrrolidin-3-yl)methyl hydrogen (2,6-dimethylphenyl)carbonimidate