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1-Methylquinazoline-2,4-dione

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Identification
Molecular formula
C9H8N2O2
CAS number
548-04-9
IUPAC name
1-methylquinazoline-2,4-dione
State
State

1-Methylquinazoline-2,4-dione is a solid at room temperature.

Melting point (Celsius)
192.00
Melting point (Kelvin)
465.20
Boiling point (Celsius)
443.20
Boiling point (Kelvin)
716.40
General information
Molecular weight
160.17g/mol
Molar mass
160.1600g/mol
Density
1.2560g/cm3
Appearence

1-Methylquinazoline-2,4-dione is typically observed as a crystalline solid. The exact color may vary, but it is generally off-white or light yellow in color. Its crystalline form highlights its purity and composition.

Comment on solubility

Solubility of 1-methylquinazoline-2,4-dione

1-methylquinazoline-2,4-dione, a compound with intriguing properties, showcases variable solubility depending on the solvent used. Here's a closer look:

  • Solubility in Water: This compound is generally poorly soluble in water, which can be attributed to its relatively hydrophobic structure.
  • Solubility in Organic Solvents: However, it demonstrates a better solubility profile in organic solvents such as:
    • Dimethyl sulfoxide (DMSO)
    • Methanol
    • Ethanol
  • Impact of pH: The solubility can also be affected by the pH of the solution, where increased acidity may enhance its dissolution in some cases.

In summary, while 1-methylquinazoline-2,4-dione may be challenging to dissolve in water, its compatibility with various organic solvents makes it quite versatile in laboratory settings. As the saying goes, “like dissolves like,” and understanding these solubility characteristics is essential for effective use in synthesis and applications.

Interesting facts

Interesting Facts about 1-methylquinazoline-2,4-dione

1-methylquinazoline-2,4-dione is a fascinating compound that straddles the realms of organic chemistry and medicinal research. This compound belongs to the quinazoline family, characterized by its unique bicyclic structure which has garnered attention due to its pharmaceutical potential. Here are some intriguing aspects of this compound:

  • Bioactive Properties: 1-methylquinazoline-2,4-dione has shown promise in various biological activities, including antibacterial and anticancer properties. This makes it a subject of interest for drug discovery and medicinal chemistry.
  • Synthesis: The synthesis of this compound is of great importance and can involve various methods such as cyclization reactions. A common route includes starting from easily obtainable anilines, showcasing the versatility in synthetic approaches.
  • Diverse Derivatives: The structural modifications of 1-methylquinazoline-2,4-dione can lead to the creation of numerous derivatives with potentially enhanced biological activities, leading to a rich field of study in drug design.
  • Literary Reference: This compound has not only been a star in laboratory settings but has also been featured in scientific literature, highlighting its relevance to both academic research and industrial applications.

In summary, 1-methylquinazoline-2,4-dione stands out due to its significant biological activities and the intriguing potential for derivative compounds. As a scientist or student in chemistry, exploring this compound offers a great opportunity to delve into the exciting frontier of medicinal chemistry.

Synonyms
Glycosmicine
1-Methyl-2,4(1H,3H)-quinazolinedione
2,4(1H,3H)-QUINAZOLINEDIONE, 1-METHYL-
NSC 401254
Methyl-1 (1H,3H)quinazolinedione-2,4
Methyl-1 (1H,3H)quinazolinedione-2,4 [French]
DTXSID20209154
DTXCID40131645
rwfoomqyirithl-uhfffaoysa-n
604-50-2
1-methylquinazoline-2,4(1H,3H)-dione
1-methylquinazoline-2,4-dione
MFCD00731030
NSC401254
1,2,3,4-tetrahydro-1-methyl-2,4-dioxoquinazoline
SCHEMBL5033267
1-Methyl-2,3H)-Quinazolinedione
ALBB-019518
2,3H)-Quinazolinedione, 1-methyl-
AKOS000266261
CCG-344340
DS-4731
NSC-401254
SY086690
1-METHYL-3H-QUINAZOLINE-2,4-DIONE
DB-072797
CS-0151121
quinazoline-2,4(1H,3H)-dione, 1-methyl-
C75825
AG-690/33347036
SR-01000467676
SR-01000467676-1