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Nifuroxazide

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Identification
Molecular formula
C12H11N3O5S
CAS number
965-52-6
IUPAC name
1-methylsulfanyl-N-[2-(5-nitro-2-furyl)cyclopenta-2,4-dien-1-ylidene]methanehydrazonothioic acid
State
State
At room temperature, Nifuroxazide is in a solid state, presenting as a crystalline powder with its distinctive yellow color.
Melting point (Celsius)
200.00
Melting point (Kelvin)
473.20
Boiling point (Celsius)
605.60
Boiling point (Kelvin)
878.80
General information
Molecular weight
275.29g/mol
Molar mass
275.2920g/mol
Density
1.5400g/cm3
Appearence

Nifuroxazide typically appears as a bright yellow crystalline powder. It is reasonably soluble in organic solvents and shows characteristic coloration.

Comment on solubility

Solubility of 1-methylsulfanyl-N-[2-(5-nitro-2-furyl)cyclopenta-2,4-dien-1-ylidene]methanehydrazonothioic acid

Understanding the solubility of 1-methylsulfanyl-N-[2-(5-nitro-2-furyl)cyclopenta-2,4-dien-1-ylidene]methanehydrazonothioic acid is essential for its potential applications in chemical research and industry. This compound exhibits unique solubility properties, which can influence its behavior in various solvents.

Key Factors Influencing Solubility:

  • Polarity: The presence of a sulfanyl group and a nitro substituent contributes to the compound’s overall polarity, making it more soluble in polar solvents.
  • Hydrogen Bonding: Potential hydrogen bonds can enhance solubility in suitable solvents due to the interactions with water molecules.
  • Molecular Structure: The cyclic and conjugated systems in its structure can cause varied solubility because of steric hindrance and electronic effects.

Generally, it is anticipated that 1-methylsulfanyl-N-[2-(5-nitro-2-furyl)cyclopenta-2,4-dien-1-ylidene]methanehydrazonothioic acid may show:

  1. Higher solubility: In polar protic solvents such as methanol or ethanol.
  2. Limited solubility: In nonpolar solvents like hexane or toluene due to its polar functional groups.

In conclusion, the solubility of this compound is a multifaceted aspect that can be significantly affected by solvent choice and molecular structure, making it critical to consider these factors in any experimental design or application involving this compound.

Interesting facts

Interesting Facts About 1-Methylsulfanyl-N-[2-(5-nitro-2-furyl)cyclopenta-2,4-dien-1-ylidene]methanehydrazonothioic Acid

1-Methylsulfanyl-N-[2-(5-nitro-2-furyl)cyclopenta-2,4-dien-1-ylidene]methanehydrazonothioic acid is a fascinating compound that showcases the intricate world of organic chemistry and its role in medicinal chemistry. Here are some noteworthy aspects of this compound:

  • Structural Complexity: The compound features a complex molecular structure that includes a unique nitrogen-based hydrazone functional group, combined with a furan ring. This structural design can lead to a variety of interesting chemical reactions.
  • Biological Relevance: Compounds with nitrogen and sulfur moieties have been studied for their potential pharmacological activities, including anti-cancer properties and antimicrobial effects. The presence of the nitro group may also enhance reactivity and biological activity.
  • Reactivity: The thioic acid component in this compound can undergo reactions typical of thiol groups, making it a potential candidate for reactions that involve nucleophilic attack.
  • Diverse Applications: The versatility of such compounds extends to materials science, where they can be explored for their roles in photoactive materials or as catalysts in organic synthesis.

“Innovations in organic synthesis are often inspired by the creativity and complexity found within nature.”
This sentiment rings especially true for compounds like 1-methylsulfanyl-N-[2-(5-nitro-2-furyl)cyclopenta-2,4-dien-1-ylidene]methanehydrazonothioic acid, which exemplify the bridge between synthetic chemistry and natural product synthesis.

In summary, the study of this compound not only advances our understanding of organic synthesis but also highlights the potential applications in a range of scientific fields, including medicinal chemistry and materials science.